Results 231 to 240 of about 101,473 (294)

Protective Effect and Mechanism of Rosiglitazone in α‐amanitin‐induced Hepatotoxicity Via Activation of PPAR‐γ/Nrf2 Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Fuping Lai, Ya Liao, Jin Wu, Tinggang Wang, Guiyi Zhang, Xiaojun Zhang, Caiyun Xia, Jie Hu, Yuanlan Lu   +8 more
wiley   +1 more source

Deciphering mutational effects on inducible NO synthase conformational dynamics via quantitative cross-linking mass spectrometry and AlphaFold2 subsampling. [PDF]

J Biol Chem
Jiang T, Zhang H, Da Silva GM, Gyawali YP, Feng C.   +4 more
europepmc   +1 more source

High‐Throughput Screen of NPQ in Sorghum Shows Highly Polygenic Architecture of Photoprotection

Plant-Environment Interactions, Volume 7, Issue 1, February 2026.
ABSTRACT Natural genetic variation in photosynthesis and photoprotection within crop germplasm represents an untapped resource for crop improvement. Sorghum bicolor (sorghum) is one of the world's most widely grown crops, yet the genetic basis of photoprotection in sorghum is not well understood.
Richard L. Vath, Samuel B. Fernandes, Brandon Monier, Katarzyna Głowacka, Julia Walter, Alexander E. Lipka, John Ferguson, Carl J. Bernacchi, Taylor Pederson, Johannes Kromdijk   +9 more
wiley   +1 more source

[Retracted] <i>In vivo</i> and <i>in vitro</i> effects of heme oxygenase-1 silencing on the survival of acute myelocytic leukemia-M2 cells. [PDF]

Exp Ther Med
Wei S, Wang Y, Chai Q, Fang Q, Zhang Y, Wang J.   +5 more
europepmc   +1 more source

Cryo‐EM reveals an ensemble of cytochrome P450 reductase conformations in solution

Protein Science, Volume 35, Issue 2, February 2026.
Abstract The eukaryotic electron transport system, mediated by cytochrome P450 reductase (CPR), plays a crucial role in driving myriads of reactions involved in the biosynthesis of physiologically active compounds (such as sterols, steroids, vitamins, and natural products), as well as in the metabolism of drugs, toxins, and carcinogens.
Galina I. Lepesheva, Tatiana Y. Hargrove, Yi Ren   +2 more
wiley   +1 more source

Analysis of Benzoate 1,2-Dioxygenase Identifies Shared Electron Transfer Components With DxnA1A2 in Rhizorhabdus wittichii RW1. [PDF]

J Basic Microbiol
Ivanovski I, Eleya S, Zylstra GJ.
europepmc   +1 more source

Development of a Physiologically Based Model of Bilirubin Metabolism in Health and Disease and Its Comparison With Real‐World Data

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Bilirubin is a breakdown product of erythrocytes and plays a crucial role in elimination of heme‐containing proteins. After its synthesis in the reticuloendothelial system, unconjugated bilirubin is released into plasma and taken up into the liver.
Ahenk Zeynep Sayin, Lars Kuepfer
wiley   +1 more source

Arachidonoyl-carnitine and arachidonoyl-coenzyme A are suitable substrates for mammalian ALOX isoforms. [PDF]

J Lipid Res
Chen X, Parvez S, Wiegand HF, Wu L, Stehling S, Borchert A, Yang J, Aparoy P, Kuhn H.   +8 more
europepmc   +1 more source

Heme oxygenase and inflammation

, 2016
Mirrin J. Dorresteijn
openalex   +1 more source

Exploring the Potential and Evaluating Hydrocarbon Degradation by Novel Antarctic Dietzia and Pusillimonas Isolates From a Pristine Environment

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
The Antarctic Dietzia and Pusillimonas isolates were tested for bioremediation applications. Genomic analyses revealed the potential to degrade complex organic compounds, potential virulence factors and resistance genes. Physiological assays showed a wide range of adaptation to abiotic factors and sensitivity to different groups of antibiotics ...
Tomasz Krucoń, Julia Karbowska, Wiktoria Pietrowicz, Robert Stasiuk, Łukasz Drewniak   +4 more
wiley   +1 more source