Results 231 to 240 of about 60,708 (241)

Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications.

Physiological Reviews, 2006
The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1, HO-2), catalyze the rate-limiting step in the metabolic conversion of heme to the bile pigments (i.e., biliverdin and bilirubin) and thus constitute a major intracellular ...
S. Ryter, J. Alam, A. Choi
semanticscholar   +1 more source

Homogeneous Oxygenase Catalysis.

Chemical Reviews, 2018
Oxygenases-catalyzed reductive activation of molecular oxygen and incorporation of O atoms into an organic molecule is undoubtedly one of the most attractive research areas.
Yu-Feng Liang, Jialiang Wei, Xu Qiu, N. Jiao   +3 more
semanticscholar   +1 more source

Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications

The FASEB Journal, 1988
In biological systems oxidation of heme is carried out by two isozymes of the microsomal heme oxygenase, HO‐1 and HO‐2. HO‐1 is the commonly known heme oxygenase, the activity of which can be induced by up to 100‐fold in response to a wide variety of ...
M. Maines
semanticscholar   +1 more source

Regulation of inflammation by the antioxidant haem oxygenase 1

Nature reviews. Immunology, 2021
Nicole K. Campbell, Hannah K. Fitzgerald, A. Dunne   +2 more
semanticscholar   +1 more source

Heme oxygenase-1 as a target for drug discovery.

Antioxidants and Redox Signaling, 2014
SIGNIFICANCE Heme oxygenase enzymes, which exist as constitutive (HO-2) and inducible (HO-1) isoforms, degrade heme to carbon monoxide (CO) and the bile pigment biliverdin.
R. Motterlini, R. Foresti
semanticscholar   +1 more source

Heme oxygenase-1 mediates BAY 11-7085 induced ferroptosis.

Cancer Letters, 2018
Ling-Chu Chang, Shih-Kai Chiang, Shuen-Ei Chen, Yung-Luen Yu, Ruey-Hwang Chou, Wei-Chao Chang   +5 more
semanticscholar   +1 more source

A review on heme oxygenase-1 induction: is it a necessary evil

Inflammation Research, 2018
A. Waza, Zeenat Hamid, Sajad Ali, S. Bhat, M. Bhat   +4 more
semanticscholar   +1 more source

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

Nature Chemical Biology, 2005
V. Kagan, V. Tyurin, Jianfei Jiang, Y. Tyurina, V. Ritov, A. Amoscato, A. Osipov, N. Belikova, A. Kapralov, V. Kini, I. I. Vlasova, Qing Zhao, Meimei Zou, Peter Y. P. Di, D. Svistunenko, I. Kurnikov, G. Borisenko   +16 more
semanticscholar   +1 more source

Heme oxygenase-1: unleashing the protective properties of heme.

Trends in immunology, 2003
L. Otterbein, M. Soares, K. Yamashita, F. Bach   +3 more
semanticscholar   +1 more source

Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice

Nature Network Boston, 2002
Tzong-Shyuan Lee, L. Chau
semanticscholar   +1 more source