Results 61 to 70 of about 60,708 (241)

Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter

Haematologica, 2013
Induction of heme oxygenase-1, a stress-inducible enzyme with anti-inflammatory activity, reduces the immunogenicity of therapeutic factor VIII in experimental hemophilia A.
Yohann Repessé, Ivan Peyron, Jordan D Dimitrov, Suryasarathi Dasgupta, Elika Farrokhi Moshai, Catherine Costa, Annie Borel-Derlon, Benoit Guillet, Roseline D’Oiron, Achille Aouba, Chantal Rothschild, Johannes Oldenburg, Anna Pavlova, Srinivas V Kaveri, Sébastien Lacroix-Desmazes   +14 more
doaj   +1 more source

Xanthophylls Modulate Palmitoylation of Mammalian β-Carotene Oxygenase 2

Antioxidants, 2021
An extensive body of work has documented the antioxidant role of xanthophylls (lutein and zeaxanthin) in human health and specifically how they provide photoprotection in human vision.
Sheetal Uppal, Sergey A. Dergunov, Weiyu Zhang, Susan Gentleman, T. Michael Redmond, Eugene Pinkhassik, Eugenia Poliakov   +6 more
doaj   +1 more source

Feruloyl oligosaccharides, isolated from bacterial fermented wheat bran, exhibit antioxidant effects in IPEC‐J2 cells and zebrafish model

Food Science &Nutrition, Volume 11, Issue 1, Page 295-306, January 2023., 2023
An excess of reactive oxygen species (ROS) can cause cell damage, and an accumulation of damage leads to cellular dysfunction resulting in a variety of diseases including abnormal aging, cancer, diabetes, and inflammation. In this study, feruloyl oligosaccharides (FOs) were obtained by solid‐state fermentation using wheat bran, and antioxidant activity
Qiuyan Chen, Jia Zhang, Yuan Wang, Ruifang Wang, Xiran Hao, Ruxin Wang, Yue Zheng, Xiaoping An, Jingwei Qi   +8 more
wiley   +1 more source

Assays for the Detection of Rubber Oxygenase Activities

Bio-Protocol, 2017
Microbial biodegradation of rubber relies on extracellular rubber oxygenases that catalyze the oxidative cleavage of the double bond of the polyisoprene backbone into oligo-isoprenoids.
Wolf Röther, Jakob Birke, Dieter Jendrossek   +2 more
doaj   +1 more source

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.

Proceedings of the National Academy of Sciences of the United States of America, 1989
We have shown that UVA (320-380 nm) radiation, hydrogen peroxide, and sodium arsenite induce a stress protein of approximately 32 kDa in human skin fibroblasts.
S. Keyse, R. Tyrrell
semanticscholar   +1 more source

Danshensu attenuated lipopolysaccharide‐induced LX‐2 and T6 cells activation through regulation of ferroptosis

Food Science &Nutrition, Volume 11, Issue 1, Page 344-349, January 2023., 2023
Danshensu (Dan) attenuates lipopolysaccharide‐induced hepatic stellate cells activation via decreasing expression of collagen І, connective tissue growth factor, glutathione peroxidase 4, cystine/glutamate antiporter xCT, and lipocalin‐2. However, Dan increases lipid reactive oxygen species accumulation.
Changting Wang, Zhiming Su, Jian‐Hua Xu, Chih‐Yuan Ko   +3 more
wiley   +1 more source

HEME OXYGENASE: ENZYME WITH FUNCTIONAL DIVERSITY [PDF]

Journal of Stress Physiology & Biochemistry, 2011
In recent years role of Heme oxygenase (HO) has been considered in nearly all living system including plants, animals and other organisms. The common role of heme oxygenase is the degradation of heme, although there is a diversity of additional role of ...
Shekhawat G. S., Dixit S., Verma K., Nasybullina E.I., Kosmachevskaya O.V., Topunov A.F.   +5 more
doaj  

Carbon monoxide: from toxin to endogenous modulator of cardiovascular functions

Brazilian Journal of Medical and Biological Research, 1999
Carbon monoxide (CO) is a pollutant commonly recognized for its toxicological attributes, including CNS and cardiovascular effects. But CO is also formed endogenously in mammalian tissues. Endogenously formed CO normally arises from heme degradation in a
R.A. Johnson, F. Kozma, E. Colombari
doaj   +1 more source

Characterization of an efficient N-oxygenase from Saccharothrix sp. and its application in the synthesis of azomycin

Biotechnology for Biofuels and Bioproducts, 2023
Background The nitro group constitutes a significant functional moiety within numerous valuable substances, such as nitroimidazoles, a class of antimicrobial drugs exhibiting broad spectrum activity.
Chuanle Fan, Fang Zhou, Wei Huang, Yi Xue, Chao Xu, Rubing Zhang, Mo Xian, Xinjun Feng   +7 more
doaj   +1 more source

The inhibitory effect of Yam polysaccharides on acrylamide‐induced programmed cell death in RAW 264.7 cells

Food Science &Nutrition, Volume 11, Issue 1, Page 443-457, January 2023., 2023
Acrylamide triggered macrophage cell apoptosis and autophagy and pyroptosis. ;P2X7 was of great significance in acrylamide‐induced cell death, but was mainly responsible for the regulation of autophagy and pyroptosis. Acrylamide stimulated oxidative stress via P2X7 in macrophage cells.
Jing Wang, Ying Han, Man Wang, He Li, Yujiao Sun, Xuefeng Chen   +5 more
wiley   +1 more source