Results 61 to 70 of about 101,473 (294)

Characterization and Function Analysis of the Beta-Carotene Oxygenase-like Genes in Carotenoids Metabolism of the Ridgetail White Prawn Exopalaemon carinicauda

Frontiers in Physiology, 2020
Carotenoids are almost universally distributed in living organisms. The oxidative metabolism by carotene oxygenase contributes to the metabolic processes of carotenoids.
Yue Jin, Yue Jin, Yue Jin, Yang Yu, Yang Yu, Yang Yu, Chengsong Zhang, Chengsong Zhang, Chengsong Zhang, Shihao Li, Shihao Li, Shihao Li, Xiaojun Zhang, Xiaojun Zhang, Xiaojun Zhang, Fuhua Li, Fuhua Li, Fuhua Li, Fuhua Li   +18 more
doaj   +1 more source

Resveratrol exhibits neuroprotection against paraquat-induced PC12 cells via heme oxygenase 1 upregulation by decreasing MiR-136-5p expression [PDF]

, 2022
Li Zhang, Min-Na Dong, Jun Deng, Zhang Chun-hai, Mingwei Liu   +4 more
openalex   +1 more source

O2‐Aktivierung an einem enzymatischen diFe‐Zentrum: Brückenligand‐Substitutionen ändern die Fe(II)/Fe(II) (Hydro)peroxo‐Bindung

Angewandte Chemie, EarlyView.
Durch Austausch der verbrückenden Carboxylate in DiFe‐Suleythrin wird die Koordination des Brückenliganden von 1,3‐Carboxylat zu 1,1‐Carboxylat verschoben, wodurch alle drei diFe(II)‐Koordinationsmotive in einem Protein entstehen. Dies verkürzt den Fe‐Fe‐Abstand und erhöht die Reaktivität mit O2.
Jae‐Hun Jeoung, Stefan Rünger, Kilian Weißer, Jakob Ruickoldt, Samriddhi Bhattacharya, Christian Limberg, Holger Dobbek   +6 more
wiley   +1 more source

Fatty acid oxygenase activity of human hair roots

Journal of Lipid Research, 1993
The extent to which fatty acid oxygenases are activated in the normal epidermis is not known. Characterization of the regio- and stereospecificity of the monohydroxylated derivatives of arachidonic and linoleic acid produced by human hair roots is needed
AN Baer, FA Green
doaj   +1 more source

Stereospecificity of the products of the fatty acid oxygenases derived from psoriatic scales.

Journal of Lipid Research, 1991
The principal in vivo oxygenase products of arachidonic acid and linoleic acid in psoriatic skin scales are 12-hydroxyeicosatetraenoic acid (R/S ratio = 5.7), 13-hydroxyoctadecadienoic acid (S/R = 1.9), and 9-hydroxyoctadecadienoic acid (R/S = 2.4 ...
AN Baer, PB Costello, FA Green
doaj   +1 more source

Structural and mutational analyses of the Leptospira interrogans virulence-related heme oxygenase provide insights into its catalytic mechanism.

PLoS ONE, 2017
Heme oxygenase from Leptospira interrogans is an important virulence factor. During catalysis, redox equivalents are provided to this enzyme by the plastidic-type ferredoxin-NADP+ reductase also found in L. interrogans.
Anabel Soldano, Sebastián Klinke, Lisandro H Otero, Mario Rivera, Daniela L Catalano-Dupuy, Eduardo A Ceccarelli   +5 more
doaj   +1 more source

O2 Activation at an Enzymatic Diiron Site: Bridging Ligand Substitutions Alter Diferric‐(Hydro)peroxo States

Angewandte Chemie International Edition, EarlyView.
Substituting the bridging carboxylates in diFe sulerythrin shifts the bridging ligand coordination from 1,3‐carboxylate to 1,1‐carboxylate, yielding all three diferrous bridging motifs in one protein. This shortens the Fe–Fe distance and increases reactivity with O2.
Jae‐Hun Jeoung, Stefan Rünger, Kilian Weißer, Jakob Ruickoldt, Samriddhi Bhattacharya, Christian Limberg, Holger Dobbek   +6 more
wiley   +1 more source

Heme oxygenase 2 is neuroprotective against intracerebral hemorrhage

Neurobiology of Disease, 2006
Recent studies suggest a neuroprotective function for heme oxygenase 2 (HO2) in acute brain injury and ischemia. HO2, the main enzyme to degrade the pro-oxidant heme, was tested for its neuroprotective ability in postnatal neuronal cell cultures and in a
Jian Wang, Hean Zhuang, Sylvain Doré
doaj   +1 more source

Heme Oxygenase–Like Metalloenzymes

Annual Review of Biochemistry
Heme oxygenase (HO)-like metalloenzymes are an emerging protein superfamily diverse in reaction outcome and mechanism. Found primarily in bacterial biosynthetic pathways, members conserve a flexible protein scaffold shared with the heme catabolic enzyme, HO, and a set of metal-binding residues.
Pope, Sarah R., McBride, Molly J., Nair, Mrutyunjay A., Salas-Sola, Xavier E., Krebs, Carsten, Bollinger, J. Martin, Boal, Amie K.   +6 more
openaire   +3 more sources

Coinfection between human immunodeficiency virus and tuberculosis: A consideration on ritonavir-related heme Oxygenase-1 pathway

Biomedical and Biotechnology Research Journal, 2019
Background: Human immunodeficiency virus (HIV) infection is an important infection seen worldwide. HIV-infected patients usually have impaired immune function and get infected with other concurrent infections.
Won Sriwijitalai, Viroj Wiwanitkit
doaj   +1 more source