Results 91 to 100 of about 82,259 (373)

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Interactions of azole-based inhibitors with human heme oxygenase [PDF]

, 2023
Tapiwa Chiura, Amanda J. Mitchell, Dakota L. Grote, Niloufar Khojandi, Ryan M. Teague, Piotr J. Mak   +5 more
openalex   +1 more source

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

Distribution and diversity of enzymes for polysaccharide degradation in fungi

Scientific Reports, 2017
Fungi are important polysaccharide degraders in the environment and for biotechnology. Here, the increasing number of sequenced fungal genomes allowed for systematic identification of genes and proteins involved in polysaccharide degradation in 218 fungi.
Renaud Berlemont
doaj   +1 more source

Does abscisic acid affect strigolactone biosynthesis? [PDF]

, 2010
Strigolactones are considered a novel class of plant hormones that, in addition to their endogenous signalling function, are exuded into the rhizosphere acting as a signal to stimulate hyphal branching of arbuscular mycorrhizal (AM) fungi and germination
Adie, Akiyama, Alder, Andrew J. Thompson, Anna K. Undas, Aroca, Auldridge, Bainbridge, Bethke, Booker, Booker, Bouwmeester, Bouwmeester, Burbidge, Carbone, Carolien Ruyter-Spira, Christmann, Cook, Cornish, Cutler, Davies, De Smet, Dunlap, Ejeta, Francel Verstappen, Fraser, Gomez-Roldan, Harrison, Harro Bouwmeester, Hernandez, Herrera-Medina, Jeschke, Jiang, Juan A. López-Ráez, Kahn, Kitahata, Li, Livak, López-Ráez, López-Ráez, López-Ráez, López-Ráez, Martin J. Sergeant, Matusova, Misson, Nitsch, Parry, Parry, Paszkowski, Patrick Mulder, Rani, Rock, Sagi, Saika, Schwartz, Schwartz, Schwartz, Sergeant, Simkin, Sorefan, Spinsanti, Strack, Sun, Tan, Tatsiana Charnikhova, Taylor, Taylor, Thompson, Thompson, Timothy D. H. Bugg, Umehara, Vogel, Wasaki, Wouter Kohlen, Yoneyama, Yoneyama, Zeevaart   +76 more
core   +4 more sources

The non-canonical functions of the heme oxygenases

OncoTarget, 2016
Heme oxygenase (HO) isoforms catalyze the conversion of heme to carbon monoxide (CO) and biliverdin with a concurrent release of iron, which can drive the synthesis of ferritin for iron sequestration.
L. Vanella, I. Barbagallo, D. Tibullo, S. Forte, A. Zappalá, G. Volti   +5 more
semanticscholar   +1 more source

Microglial Membranes Wrapped Ultrasmall Medium‐Entropy Ru Single‐Atom Nanozyme: Enhanced Catalysis for Accelerating Inflammation/Redox Microenvironment Regulation in Intracerebral Hemorrhage

Advanced Science, EarlyView.
PtRhIr/Ru SAN@M nanozymes cross the blood–brain barrier and selectively accumulate in hemorrhagic brain regions. By mimicking multiple enzyme activities, they attenuate oxidative stress, modulate microglial polarization toward an anti‐inflammatory phenotype, inhibit ferroptosis, and promote neuronal repair.
Jiebo Li, Penghui Wei, Yuanbo Pan, Hongjia Zheng, Jiajun Hu, Qianxi Chen, Zhongyuan Shen, Yongrui Hu, Jiajun Wu, Fuxin Lin, Fuxiang Chen, Chenyu Ding, Wenhua Fang, Yuanxiang Lin, Dezhi Kang, Yuxiang Gu, Yang Zhu, Dengliang Wang   +17 more
wiley   +1 more source

Biocatalysis. Biological systems for the production of chemicals [PDF]

, 2017
Biocatalysis harnesses the catalytic potential of enzymes to produce building blocks and end-products for the pharmaceutical and chemical industry. Located at the interface between fermentation processes and petrol-based chemistry, biotransformation ...
Held, M., Schmid, A., van Beilen, J. B., Witholt, B.   +3 more
core  

A novel high-content immunofluorescence assay as a tool to identify at the single cell level γ-globin inducing compounds [PDF]

, 2015
The identification of drugs capable of reactivating γ-globin to ameliorate β-thalassemia and Sickle Cell anemia is still a challenge, as available γ-globin inducers still have limited clinical indications.
Antonella Ronchi, Cristina Fugazza, Fabio Gasparri, Gloria Barbarani, Isaura Font-Monclus, Ivan Fraietta, Maria Franca Marongiu, Maria Giuseppina Marini, Mario Mauri, Marta Durlak, Paolo Cappella, Paolo Cappella, Paolo Moi, Sergio Ottolenghi, Sudharshan Elangovan   +14 more
core   +4 more sources