Physiological modeling of isoprene dynamics in exhaled breath [PDF]
Human breath contains a myriad of endogenous volatile organic compounds (VOCs) which are reflective of ongoing metabolic or physiological processes.
King, Julian+8 more
core +6 more sources
Distribution and diversity of enzymes for polysaccharide degradation in fungi
Fungi are important polysaccharide degraders in the environment and for biotechnology. Here, the increasing number of sequenced fungal genomes allowed for systematic identification of genes and proteins involved in polysaccharide degradation in 218 fungi.
Renaud Berlemont
doaj +1 more source
Does abscisic acid affect strigolactone biosynthesis? [PDF]
Strigolactones are considered a novel class of plant hormones that, in addition to their endogenous signalling function, are exuded into the rhizosphere acting as a signal to stimulate hyphal branching of arbuscular mycorrhizal (AM) fungi and germination
Adie+76 more
core +4 more sources
A Charge‐Adhesive Targeted DNA Gel Bandage for the Precision Treatment of Inflammatory Bowel Disease
DNA gel bandage (DNAgb) is designed to precisely target the site of inflammation of IBD, by achieving dual specific localization of inflamed mucosa through electrostatic interactions and ApITGA4‐mediated affinity targeting. DNAgb effectively the activation of inflammatory pathways and reshapes the immune microenvironment.
Peifen Lu+9 more
wiley +1 more source
Haem oxygenase: a reappraisal of the stoicheiometry
Haem oxygenase (EC 1.14.99.3) in rat liver microsomes was first described as a mixed function oxidase utilising cytochrome P-450 [I]. Immunochemical studies suggest that NADP(H)-cytochrome c reductase activity is an essential component of the enzyme [2]. Indeed, it has been suggested [3] following the use of partially purified enzyme preparations, that
Owen T.G. Jones+2 more
openaire +3 more sources
Reduction of trimethylamine N-oxide to trimethylamine by the human gut microbiota: supporting evidence for ‘metabolic retroversion’ [PDF]
Dietary sources of methylamines such as choline, trimethylamine (TMA), trimethylamine N-oxide (TMAO), phosphatidylcholine (PC) and carnitine are present in a number of foodstuffs, including meat, fish, nuts and eggs.
Chilloux, J+4 more
core
Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size [PDF]
Calcium-independent phospholipase A(2)γ (iPLA(2)γ) is a mitochondrial enzyme that produces lipid second messengers that facilitate opening of the mitochondrial permeability transition pore (mPTP) and contribute to the production of oxidized fatty acids ...
Abendschein, Dana+12 more
core +2 more sources
The novel microneedle patches (MN@CTB) are fabricated by integrating CTB nanozymes into HAMA and PVA solution based on a photo‐crosslinking reaction. The MN@CTB microneedle patches present an excellent photothermal effect and NIR‐stimulated release of NO, which is advantageous for the elimination of MRS.
Wei Qian+13 more
wiley +1 more source
The ferroheme (FH) and exceedingly small magnetic iron oxide nanoparticles (IO) loaded mesoporous calcium peroxide nanocuboid (MCPNC) with conjugation of hyaluronic acid (HA) possesses exceptional capability of tumor accumulation, and enhances therapeutic efficacy of tumors based on the mechanism of promoting a positive feedback loop of Fenton reaction
Qingdeng Fan+17 more
wiley +1 more source
Characterized cis-FeV(O)(OH) intermediate mimics enzymatic oxidations in the gas phase
FeV(O)(OH) species have long been thought to play a role in a range of enzymatic oxidations, but their characterization has remained elusive. Here, using gas-phase ion spectroscopy, the authors characterize an FeV(O)(OH) species and find that its ...
Margarida Borrell+4 more
doaj +1 more source