Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait +5 more
wiley +1 more source
Draft genome sequence of the meloxicam-degrading <i>Gordonia alkanivorans</i> IEGM 1277 strain. [PDF]
Tyan SM, Ivshina IB.
europepmc +1 more source
Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li +3 more
wiley +1 more source
Mechanistic Insights into Dioxygen Transport Routes in the PHD2 Oxygenase from Long-Time Scale Simulations. [PDF]
Wiley B, Furini S, Domene C.
europepmc +1 more source
Ferroptosis: Newly Emerged Regulator for Human Disease
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao +4 more
wiley +1 more source
Unspecific Peroxygenases-Catalyzed Oxidation of Pharmaceutical Compounds Considered Emerging Contaminants. [PDF]
Torres-Aguirre A +4 more
europepmc +1 more source
Discovery of a Two-Step Enzyme Cascade Converting Aspartate to Aminomalonate in Peptide Natural Product Biosynthesis. [PDF]
Kim HW +7 more
europepmc +1 more source
Structure, characterisation and application of an unspecific peroxygenase from <i>Daldinia childiae</i>. [PDF]
McKenzie A +10 more
europepmc +1 more source
The detoxification paradox: Rethinking microbial dehalogenation in environmental remediation. [PDF]
Wang Q, Wang S, Hu Y, Wu J, Niu S.
europepmc +1 more source

