Results 231 to 240 of about 24,557 (298)
Oxygen needs sulfur, sulfur needs oxygen: a relationship of interdependence. [PDF]
Sekine H, Akaike T, Motohashi H.
europepmc +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Recent Advances in Bioinspired Cu-Directed C-H Hydroxylation Reactions. [PDF]
Goswami S, Garcia-Bosch I.
europepmc +1 more source
Chronic inflammation in diabetic foot ulcers elevates MMP activity and suppresses TIMP and growth factor signaling, impairing tissue repair. Phytochemicals modulate NF‐κB/MAPK pathways and enhance Nrf2–TIMP expression, restoring MMP/TIMP balance, promoting collagen deposition, angiogenesis, and re‐epithelialization, leading to effective wound healing ...
Vishnu Priyan Elaiyaraja +3 more
wiley +1 more source
Structural basis of a 2-oxoglutarate-dependent heme-oxygenase-like enzyme HamA in fragin biosynthesis. [PDF]
Su B, Zhang T, Yu Y, Liu H.
europepmc +1 more source
ABSTRACT Kaempferol has been shown to be beneficial in the treatment of Alzheimer's disease (AD) in animal models. However, the action mechanism remains unclear. AKR1B1 has been identified as a target of kaempferol, initially suggested by the Therapeutic Target Database, DrugBank, and PubChem, and subsequently confirmed through experimental validation.
Le Li +5 more
wiley +1 more source
Discovery of Partner Protein-Dependent Graspetide Biosynthesis. [PDF]
Carter RS +4 more
europepmc +1 more source
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan +3 more
wiley +1 more source
Biocatalytic Strategies for Nitration Reactions. [PDF]
Wang X, Aleotti M, Hall M, Cong Z.
europepmc +1 more source
The A101 accession is the first confirmed case of hydroxyphenyl pyruvate dioxygenase resistance in Amaranthus tuberculatus in Wisconsin, and the first report of P450s associated with atrazine resistance in A. tuberculatus globally. Abstract BACKGROUND A preliminary screening identified a multiple herbicide‐resistant waterhemp, Amaranthus tuberculatus ...
Felipe A. Faleco +8 more
wiley +1 more source

