Results 71 to 80 of about 13,374 (242)
Heme Oxygenase and Atherosclerosis [PDF]
Overproduction of reactive oxygen species under pathophysiological conditions, including dyslipidemia, hypertension, diabetes, and smoking, is integral in the development of cardiovascular diseases (CVD). The reactive oxygen species released from all types of vascular cells regulate various signaling pathways that mediate not only vascular inflammation
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The correlation between the structures of metal complexes immobilized in the mesopores of hydrophobically modified silicate supports was examined in relation to the catalytic activities toward C‐H oxidation. On the alkene oxidation with H2O2, the iron catalyst bearing bis(imidazolyl)methane ligand promotes allylic oxidation, whereas the mononuclear ...
Yuta Akizawa +8 more
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Oxylipins, a class of oxygenase-derived unsaturated fatty acids, are important signal molecules in many biological systems. Recent characterization of an Aspergillus flavus lipoxygenase gene, lox, revealed its importance in maintaining a density ...
Sigal Horowitz Brown +6 more
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Crystalline l-Lysine Oxygenase
Abstract l-Lysine oxygenase has been purified about 100-fold from cells of Pseudomonas fluorescens and crystallized. The crystalline enzyme contains 2 moles of flavin adenine dinucleotide per mole of enzyme, the molecular weight of which has been estimated to be 191,000.
H, Takeda, O, Hayaishi
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Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
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Carotinoid-Oxygenase in Chlorella
In Chlorella wurde ein bisher unbekanntes labiles Oxygenasesystem gefunden, das im Dunkeln mit großer Geschwindigkeit Sauerstoff auf Carotinoide überträgt und das durch Licht gehemmt wird. Vgl. dazu O. WARBURG, G. KRIPPAHL und W. SCHRÖDER, Wirkungsspektrum eines Photosynthese-Ferments, diese Z. 10 b, 631 [1955].
O, WARBURG +3 more
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This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng +5 more
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Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities.
The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno adducts on the nucleobases ...
Daria Zdżalik +10 more
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Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
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ABSTRACT This study aimed to evaluate the toxicological effects of occupational exposure to factory‐derived particulate matter (PM2.5) on human skin, emphasizing its role as a potential target organ of environmental toxicants. An epidemiological survey comparing factory and nonfactory workers was conducted by assessing their skin elasticity and color ...
Miku Tanaka +7 more
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