Results 101 to 110 of about 9,312 (214)

Development of an Optimized LC-MS Method for the Detection of Specialized Pro-Resolving Mediators in Biological Samples

open access: yesFrontiers in Pharmacology, 2019
The cardioprotective and anti-inflammatory effects of long chain omega-3 polyunsaturated fatty acids (n3 PUFA) are believed to be partly mediated by their oxygenated metabolites (oxylipins).
Laura Kutzner   +9 more
doaj   +1 more source

Q&A: How does jasmonate signaling enable plants to adapt and survive? [PDF]

open access: yes, 2016
Jasmonates (JAs) are a class of plant hormones that play essential roles in response to tissue wounding. They act on gene expression to slow down growth and to redirect metabolism towards producing defense molecules and repairing damage.
Larrieu, A, Vernoux, T
core   +3 more sources

Reduced triacylglycerols and lipid droplets are associated with resilience to Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Although it has become clear that alterations in lipid metabolism are associated with Alzheimer's disease (AD), it is unclear how they contribute to both cognitive decline and the pathophysiology of AD. METHODS Lipidomics and activity‐based protein profiling (ABPP) were performed in the frontal cortex of control, AD and resilient ...
Daan van der Vliet   +12 more
wiley   +1 more source

The emerging role of oxylipins in thrombosis and diabetes. [PDF]

open access: yes, 2014
The prevalence of cardiovascular disease (CVD), the leading cause of death in the US, is predicted to increase due to the shift in age of the general population and increase in CVD risk factors such as obesity and diabetes.
Ahmed, Intekhab   +2 more
core   +3 more sources

Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Their bioactive constituents act through antioxidant, anti‐inflammatory, and metabolic‐regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings.
Nighat Raza   +7 more
wiley   +1 more source

Lipid mediator metabolic profiling demonstrates differences in eicosanoid patterns in two phenotypically distinct mast cell populations[S]

open access: yesJournal of Lipid Research, 2013
Mast cells are inflammatory cells that play key roles in health and disease. They are distributed in all tissues and appear in two main phenotypes, connective tissue and mucosal mast cells, with differing capacities to release inflammatory mediators.
Susanna L. Lundström   +5 more
doaj   +1 more source

In silico/in vivo insights into the functional and evolutionary pathway of Pseudomonas aeruginosa oleate-diol synthase. Discovery of a new bacterial di-heme cytochrome C peroxidase subfamily [PDF]

open access: yes, 2015
As previously reported, P. aeruginosa genes PA2077 and PA2078 code for 10S-DOX (10S-Dioxygenase) and 7,10-DS (7,10-Diol Synthase) enzymes involved in long-chain fatty acid oxygenation through the recently described oleate-diol synthase pathway.
Barril Alonso, Xavier   +4 more
core   +1 more source

Lipidomic and Metagenomic Profiling of Chinese Female Emerging Adults With Oily Scalp

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Excessive sebum secretion leads to oily scalps, which can disturb microbial homeostasis and cause various scalp issues, such as sensitive scalp, dandruff, and seborrheic dermatitis. Aims This study aimed to investigate the characteristics of scalp lipids and microbiota in a group of females with excessive sebum secretion using omics
Fang Yang   +7 more
wiley   +1 more source

Structural Evidence for the Substrate Channeling of Rice Allene Oxide Cyclase in Biologically Analogous Nazarov Reaction

open access: yesFrontiers in Chemistry, 2018
Allene oxide cyclase (AOC) is a key enzyme in the jasmonic acid (JA) biosynthetic pathway in plants, during which it catalyzes stereospecific conversion of 12,13(S)-epoxy-9(Z),11,15(Z)-octadecatrienoic acid (12,13-EOT) to cis(+)-12-oxophytodienoic acid ...
Sereyvath Yoeun   +3 more
doaj   +1 more source

Evolution of molecular communication in the permanent Azolla symbiosis

open access: yesNew Phytologist, Volume 249, Issue 4, Page 1666-1674, February 2026.
Summary Heritable symbioses exist across eukaryotes with different degrees of intimacy. In most cases, the symbionts are obligate and require inheritance for their survival. On the host side, symbiont retention can facilitate fitness benefits. Only rarely are these symbioses interwoven to the point that host survival relies on the symbiont.
Deren Büyüktaş   +2 more
wiley   +1 more source

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