Results 81 to 90 of about 2,408 (164)

The emerging role of oxylipins in thrombosis and diabetes [PDF]

Frontiers in Pharmacology, 2014
The prevalence of cardiovascular disease (CVD), the leading cause of death in the US, is predicted to increase due to the shift in age of the general population and increase in CVD risk factors such as obesity and diabetes. New therapies are required to decrease the prevalence of CVD risk factors (obesity and diabetes) as well as reduce ...
Tourdot, Benjamin E, Ahmed, Intekhab, Holinstat, Michael   +2 more
openaire   +3 more sources

Oxylipins‐Omics Combine With Single‐Molecule Analysis Identifies 13(S)‐HODE Positive Extracellular Vesicles as a Diagnostic Biomarker for AFP‐Negative Hepatocellular Carcinoma

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Our work identifies EV‐derived 13(S)‐HODE as a novel biomarker for HCC, establishes a single‐molecule platform for EV lipid analysis, and constructs a high‐performance diagnostic model by integrating multi‐dimensional data, offering new potential strategies for early monitoring and precise diagnosis of HCC.2 ABSTRACT Efficient diagnostic biomarkers ...
Yu Wang, Qiaoting Wu, Huixian Lin, Xiaoqing Jiang, Zhenxun Wang, Chao Yang, Rong Wang, Bo Ma, Yingxue Shen, Jiawei Li, Jiaming Chen, Wanyang Sun, Rongrong He, Lei Zheng, Chunchen Liu, Xin Zhang   +15 more
wiley   +1 more source

Changes of lipid metabolism of Arabidopsis thaliana in response to oligochitosan treatment

Biologia Plantarum, 2020
Lipids are vital cellular constituents in plant, and lipid peroxidation metabolites are critical defence substances in plants. In this study, mass spectrometry along with projections to latent structures discriminant analysis (PLS-DA) was used to detect ...
X.J. WANG, X.L. SU, J.M. LI, P. ZHU
doaj   +1 more source

Metabolic Syndrome: From Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 9, September 2026.
A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley   +1 more source

Oxylipins and Plant Palatability [PDF]

The Plant Cell, 2012
Oxylipins are a large family of oxygenated fatty acids that play important roles in plant development and responses to physical damage caused by herbivores, insects, and attack by pathogenic microorganisms ([Howe and Jander, 2008][1]; [Wu and Baldwin, 2010][2]).
openaire   +1 more source

Oxylipin dynamics in dairy cows during clinical ketosis and after treatment with niacin and flunixin meglumine

JDS Communications
Dairy cows with clinical ketosis (CK) exhibit metabolic changes, including intense adipose tissue (AT) lipolysis and systemic insulin resistance, that increase plasma BHB and free fatty acids (FFA).
Miguel Chirivi, Daniela Cortes-Beltran, Jeff Gandy, G. Andres Contreras   +3 more
doaj   +1 more source

Lipid mediator metabolic profiling demonstrates differences in eicosanoid patterns in two phenotypically distinct mast cell populations[S]

Journal of Lipid Research, 2013
Mast cells are inflammatory cells that play key roles in health and disease. They are distributed in all tissues and appear in two main phenotypes, connective tissue and mucosal mast cells, with differing capacities to release inflammatory mediators.
Susanna L. Lundström, Rohit Saluja, Mikael Adner, Jesper Z. Haeggström, Gunnar Nilsson, Craig E. Wheelock   +5 more
doaj   +1 more source

Systemic acquired resistance: an emerging role for jasmonates in local signal biogenesis, translocation and distal signal decoding

New Phytologist, Volume 251, Issue 6, Page 3142-3158, September 2026.
Jasmonate signalling underpins establishment of plant systemic acquired resistance (SAR). Activation of the hypersensitive response (HR) not only contains the pathogen but establishes broad spectrum resistance in unchallenged leaves. The strong burst of reactive oxygen/nitrogen species initiating the HR results in lipid peroxidation (illustrated by ...
Fay Bennett, Erin Stroud, Pradeep Kachroo, Murray Grant   +3 more
wiley   +1 more source

Structural Evidence for the Substrate Channeling of Rice Allene Oxide Cyclase in Biologically Analogous Nazarov Reaction

Frontiers in Chemistry, 2018
Allene oxide cyclase (AOC) is a key enzyme in the jasmonic acid (JA) biosynthetic pathway in plants, during which it catalyzes stereospecific conversion of 12,13(S)-epoxy-9(Z),11,15(Z)-octadecatrienoic acid (12,13-EOT) to cis(+)-12-oxophytodienoic acid ...
Sereyvath Yoeun, Sereyvath Yoeun, Kyoungwon Cho, Oksoo Han   +3 more
doaj   +1 more source

The SVP–FRO6 Module Integrates the Control of Leaf Senescence and Flowering in Arabidopsis

Plant, Cell &Environment, Volume 49, Issue 9, Page 7191-7209, September 2026.
ABSTRACT Plants coordinate major developmental transitions by integrating intrinsic genetic programs with environmental signals, where nutrient availability serves as a critical external factor shaping growth and fitness. Iron (Fe), an essential micronutrient for cellular respiration and photosynthesis, is strictly regulated through sophisticated ...
Hyunsu Park, Yeong Seon Yoon, Sanghoon Park, Ukcheol Jeong, Hyeyoung Choi, Hyunwoo Oh, Dovran Shamamedov, Zhonghai Li, Hye Ryun Woo   +8 more
wiley   +1 more source