Results 61 to 70 of about 2,408 (164)

Oxylipin transport by lipoprotein particles and its functional implications for cardiometabolic and neurological disorders [PDF]

Lipoprotein metabolism is critical to inflammation. While the periphery and central nervous system (CNS) have separate yet connected lipoprotein systems, impaired lipoprotein metabolism is implicated in both cardiometabolic and neurological disorders ...
Liang, Nuanyi, Newman, John W, Zhou, Sitong, Kaddurah-Daouk, Rima, Borkowski, Kamil, Harsch, Brian A, Shearer, Gregory C, Borkowska, Alison   +7 more
core   +1 more source

The Oxylipin Pathways: Biochemistry and Function

Annual Review of Plant Biology, 2018
Plant oxylipins form a constantly growing group of signaling molecules that comprise oxygenated fatty acids and metabolites derived therefrom. In the last decade, the understanding of biosynthesis, metabolism, and action of oxylipins, especially jasmonates, has dramatically improved.
Wasternack, Claus, Feussner, Ivo
openaire   +3 more sources

Comprehensive Analysis of Different Subtypes of Oxylipins to Determine a LC–MS/MS Approach in Clinical Research

Metabolites
Background/Objectives: Different oxylipin subtypes have unique biological properties, requiring effective analytical protocols. However, establishing a complete pathway detection protocol for comprehensive oxylipin analysis is challenging.
Yurou Zhao, Zhengyu Fang, Zeyu Li, Yizhe Liu, Yang Bai, Xiaoqing Wang, Hongjun Yang, Na Guo   +7 more
doaj   +1 more source

Detoxification of Reactive Carbonyl Species by Glutathione Transferase Tau Isozymes

Frontiers in Plant Science, 2019
Oxidative stimuli to living cells results in the formation of lipid peroxides, from which various aldehydes and ketones (oxylipin carbonyls) are inevitably produced.
Jun’ichi Mano, Sayaka Kanameda, Rika Kuramitsu, Nagisa Matsuura, Yasuo Yamauchi   +4 more
doaj   +1 more source

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source

Oxylipin levels, by intervention arm: Median (interquartile range).

, 2018
Oxylipin levels, by intervention arm: Median (interquartile range).
Bruce D. Hammock (65754), Jessica A. Martinez (2297254), Denise J. Roe (429202), Jun Yang (2084), David S. Alberts (3024495), Patricia A. Thompson (209907), Betsy C. Wertheim (5146601), Peter Lance (198534), Alexander Schriewer (4184308)   +8 more
core   +1 more source

Iron chelation targets lipid metabolism to reduce white matter injury in germinal matrix hemorrhage

Cell Death and Disease
Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) leads to neural cell death and inflammation, resulting in white matter injury in premature infants.
Bokun Cheng, Akanksha Mishra, Xusheng Zhang, Zaw Myo Hein, Nourelhoda Gouda, Karen Schaeffer, Mikhail Kislin, Yunping Qiu, Fereshteh Zandkarimi, Irwin J. Kurland, Praveen Ballabh   +10 more
doaj   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

Linoleic Acid Enhances Murine Natural Killer Cell Function In Vitro but Compromises Mitochondrial Bioenergetic Function During Retroviral Infection

Immunology, EarlyView.
Natural Killer (NK) cells are potent effectors against virus‐infected and tumour cells. During Friend Virus (FV) infection, fatty acid metabolism supports NK‐cell effector functions. Here, we found that NK cells from FV‐infected mice preferentially take up linoleic acid (LA), which reduced proliferation, mitochondrial function, and increased reactive ...
Vaasudevan Sridhar, Simone Schimmer, Tanja Werner, Rachel Giesen, Mohamed Saad, Constantin P. Krempe, Sven W. Meckelmann, Ulf Dittmer, Elisabeth Littwitz‐Salomon   +8 more
wiley   +1 more source

Volatile organic compounds orchestrating microbiome‐mediated crop resilience: Prospects and challenges for sustainable agriculture

Journal of Integrative Plant Biology, EarlyView.
Herbivory triggers the production of green leaf volatiles, and dense planting results in induces increased concentration of linalool emission in maize canopies. These volatiles activate plant‐soil feedback that enriches beneficial rhizosphere bacteria, enhancing resistance, though sometimes at a growth cost, thereby offering new avenues for sustainable
Peiguo Yuan, Esau De la Vega‐Camarillo, Michael V. Kolomiets, Sanjay Antony‐Babu   +3 more
wiley   +1 more source