Results 61 to 70 of about 9,479 (223)

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

The prognostic and therapeutic significance of polyunsaturated fatty acid‐derived oxylipins in ST‐segment elevation myocardial infarction

iMeta
Polyunsaturated fatty acid‐derived oxylipins regulate systemic inflammation and exert cardiovascular effects, yet their role in ST‐segment elevation myocardial infarction (STEMI) remains unclear. Herein, we used targeted metabolomics and machine learning
Zhiyong Du, Yingyuan Lu, Ying Ma, Yunxiao Yang, Wei Luo, Sheng Liu, Ming Zhang, Yong Wang, Lei Li, Chun Li, Wei Wang, Hai Gao   +11 more
doaj   +1 more source

Loss of the mammalian G-protein coupled receptor, G2A, modulates severity of invasive pulmonary aspergillosis

Frontiers in Immunology, 2023
BackgroundAspergillus fumigatus is a well-known opportunistic pathogen that causes a range of diseases including the often-fatal disease, invasive pulmonary aspergillosis (IPA), in immunocompromised populations.
Breanne N. Steffan, Dante Calise, Sung Chul Park, Mengyao Niu, Jun Yang, Bruce D. Hammock, MaryJane Jones, Chad Steele, Nancy P. Keller, Nancy P. Keller   +9 more
doaj   +1 more source

Associated bacteria affect sexual reproduction by altering gene expression and metabolic processes in a biofilm inhabiting diatom [PDF]

, 2019
Diatoms are unicellular algae with a fundamental role in global biogeochemical cycles as major primary producers at the base of aquatic food webs. In recent years, chemical communication between diatoms and associated bacteria has emerged as a key factor
Bilcke, Gust, Cirri, Emilio, De Decker, Sam, De Veylder, Lieven, Osuna, Cristina, Pohnert, Georg, Vandepoele, Klaas, Vyverman, Wim, Werner, Markus, Werz, Oliver   +9 more
core   +2 more sources

OsEUL lectin gene expression in rice : stress regulation, subcellular localization and tissue specificity [PDF]

, 2020
The Euonymus lectin (EUL) family is a unique group of carbohydrate-binding proteins that is omnipresent in plants. Sequences encoding EUL-related lectins have been retrieved from all completely sequenced plant genomes.
De Zaeytijd, Jeroen, Demirel Asci, Sinem, Dubiel, Malgorzata, Lambin, Jeroen, Smagghe, Guy, Subramanyam, Kondeti, Tsaneva, Mariya Tsankova, Van Damme, Els, Verbeke, Isabel, Wytynck, Pieter   +9 more
core   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice [PDF]

, 2016
Aim 20-hydroxyeicosatetraenoic acid (20-HETE) and epoxyeicosatrienoic acids (EETs) are cytochrome P450 (CYP)-dependent eicosanoids that play opposite roles in the regulation of vascular tone, inflammation, and apoptosis.
Blum, Maximilian, Bubalo, Gordana, Catar, Rusan Ali, Dragun, Duska, Fechner, Mandy, Gürgen, Dennis, Hoff, Uwe, Philippe, Aurelie, Rothe, Michael, Schunck, Wolf-Hagen, Weldon, Steven M., Wesser, Tim, Westphal, Christina, Wu, Kaiyin, Zhu, Ye   +14 more
core   +4 more sources

Selenomethionine Regulates the Arachidonic Acid Metabolism‐Ferroptosis‐Inflammation Axis to Ameliorate Colitis

Animal Research and One Health, EarlyView.
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian, Longzhu Zhou, Xiaohui Feng, Jialu Shen, Xiaoping Du, Qingyu Zhao, Yuchang Qin, Junmin Zhang, Chaohua Tang   +8 more
wiley   +1 more source

(10E,15Z)-12-(Dimethylsulfonio)-9,13-dihydroxyoctadeca-10,15-dienoate

Molbank
A novel oxylipin, okeanoate (1), was isolated from the Okinawan cyanobacterium Okeania hirsuta. The structure of 1 was elucidated based on spectroscopic data including 1D and 2D NMR, as well as high-resolution mass spectrometry.
Haruka Nishino, Bo-Tao Zhang, Hajime Uchida, Michiya Kamio, Hiroshi Nagai, Masayuki Satake   +5 more
doaj   +1 more source

Synthesis of Oxylipin Mimics and Their Antifungal Activity against the Citrus Postharvest Pathogens

Molecules, 2016
Nine oxylipin mimics were designed and synthesized starting from d-mannose. Their antifungal activity against three citrus postharvest pathogens was evaluated by spore germination assay.
Jimei Ma, Yupeng Li, Hangwei Chen, Zhen Zeng, Zi-Long Li, Hong Jiang   +5 more
doaj   +1 more source