Results 41 to 50 of about 2,408 (164)

The Partitioning of Newly Assimilated Linoleic and α-Linolenic Acids Between Synthesis of Longer-Chain Polyunsaturated Fatty Acids and Hydroxyoctadecaenoic Acids Is a Putative Branch Point in T-Cell Essential Fatty Acid Metabolism

Frontiers in Immunology, 2021
Longer-chain polyunsaturated fatty acids (LCPUFAs) ≥20 carbons long are required for leukocyte function. These can be obtained from the diet, but there is some evidence that leukocytes can convert essential fatty acids (EFAs) into LCPUFAs. We used stable
Johanna von Gerichten, Annette L. West, Nicola A. Irvine, Elizabeth A. Miles, Philip C. Calder, Philip C. Calder, Karen A. Lillycrop, Barbara A. Fielding, Graham C. Burdge   +8 more
doaj   +1 more source

Oxylipin Signaling and Plant Growth

, 2010
Oxylipins are derived from the oxidation of polyunsaturated fatty acids. Further conversion of the resulting fatty acid hydroperoxides gives rise to a multitude of oxylipin classes, including hydroxy-, oxo-, or keto fatty acids, volatile aldehydes, and ...
Heilmann, Ingo, Munnik, Teun, Mosblech, Alina, Feussner, Ivo   +3 more
core   +1 more source

Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks

International audienceOxylipins are major immunomodulating mediators, yet studies of inflammation focus mainly on cytokines. Here, using a standardized whole-blood stimulation system, we characterized the oxylipin-driven inflammatory responses to various
Kampschulte, Nadja, Bilek, Nicole, Mainka, Malwina, Chanson, Aurélie, Schebb, Nils, Helge, Quintana-Murci, Lluis, Villain, Etienne, Le Faouder, Pauline, Brandolini, Marion, Charbit, Bruno, Duffy, Darragh, Gladine, Cécile, Scriba, Thomas, J, Bertrand-Michel, Justine, Musvosvi, Munyaradzi   +14 more
core   +6 more sources

Multifunctional Enzymes in Oxylipin Metabolism

ChemBioChem, 2008
Fingers in lots of pies: For the first time a member of the CYP74 enzyme subfamily (9‐AOS) from tomato has been shown by chemical and analytical approaches to catalyze multiple reactions. These multifunctional properties of 9‐AOS from the oxylipin‐forming lipoxygenase (LOX) pathway raise several new questions on lipid‐derived signaling.
Wasternack, Claus, Feussner, Ivo
openaire   +3 more sources

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science
Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction ...
Julia C. Kelliher, Saranna Fanning
doaj   +1 more source

Oxylipin composition of high-density lipoprotein is altered in men and Hispanic adults with mild cognitive impairment

Journal of Lipid Research
High-density lipoprotein (HDL) oxylipins are potent inflammatory mediators. HDL dyshomeostasis and inflammation increase mild cognitive impairment (MCI) and dementia risk, which vary by gender and race/ethnicity.
Julia C. Kelliher, Christopher G. Engeland, Jennifer E. Graham-Engeland, Mindy Katz, Claudette Kessler, Gregory C. Shearer   +5 more
doaj   +1 more source

Epoxy-Oxylipins and Soluble Epoxide Hydrolase Metabolic Pathway as Targets for NSAID-Induced Gastroenteropathy and Inflammation-Associated Carcinogenesis

Frontiers in Pharmacology, 2019
Polyunsaturated fatty acids (PUFAs) including epoxide-modified ω-3 and ω-6 fatty acids are made via oxidation to create highly polarized carbon-oxygen bonds crucial to their function as signaling molecules.
Ryan D. Jones, Jie Liao, Xin Tong, Dandan Xu, Leyu Sun, Haonan Li, Guang-Yu Yang   +6 more
doaj   +1 more source

Underground Signals: The Ecological Power of Root Volatiles

Advanced Science, EarlyView.
Root volatiles mediate rhizosphere chemical communication, shaping interactions among plants, microbes, herbivores, and natural enemies. Their production, transport, and perception underpin ecological adaptation, multitrophic interactions, and plant resilience, offering opportunities for sustainable crop protection, resilient agroecosystems, and ...
Xueyao Cao, Nanli Song, François Verheggen, Meritxell Pérez‐Hedo, Andrea Clavijo McCormick, Antonino Cusumano, Arthur de Fouchier, Bing Wang, Chen‐Zhu Wang, Emmanuelle Jacquin‐Joly, Gary W. Felton, Geoff M. Gurr, Hao Guo, Jiancai Li, Jin Zhang, Li Chen, Manqun Wang, Michele Ricupero, Peng Han, Peng He, Qi Yan, Qingbo Tang, Qingsong Liu, Shiheng An, Xiangbo Kong, Xiaoling Sun, Xueming Ren, Yuanyuan Song, Yang Liu, Yanhui Guo, Yunhe Li, Xiao Sun   +31 more
wiley   +1 more source

Fusarium verticillioides and maize interaction in vitro: relation between oxylipin cross-talk and fumonisin synthesis.

, 2013
Fusarium verticillioides is one of the most important fungal pathogens to cause ear and stalk rot in maize, even if frequently asymptomatic, producing the harmful series of compounds named fumonisins.
FABBRI, Anna Adele, V. Scala, C. Fanelli, C. Dall'Asta, A.A. Fabbri, LUDOVICI, MATTEO, P. Giorni, P. Battilani, Giorni, Paola, Battilani, Paola, C. Bello, M. Reverberi, E. Camera, FANELLI, Corrado, M. Cirlini, SCALA, VALERIA, M. Ludovici, REVERBERI, Massimo   +17 more
core   +2 more sources

Loss of the mammalian G-protein coupled receptor, G2A, modulates severity of invasive pulmonary aspergillosis

Frontiers in Immunology, 2023
BackgroundAspergillus fumigatus is a well-known opportunistic pathogen that causes a range of diseases including the often-fatal disease, invasive pulmonary aspergillosis (IPA), in immunocompromised populations.
Breanne N. Steffan, Dante Calise, Sung Chul Park, Mengyao Niu, Jun Yang, Bruce D. Hammock, MaryJane Jones, Chad Steele, Nancy P. Keller, Nancy P. Keller   +9 more
doaj   +1 more source