Results 41 to 50 of about 5,905 (213)

Absolute quantification and characterization of oxylipins in lupus nephritis and systemic lupus erythematosus

Frontiers in Immunology, 2022
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with multi-organ inflammation and defect, which is linked to many molecule mediators. Oxylipins as a class of lipid mediator have not been broadly investigated in SLE.
Jingquan He, Jingquan He, Chiyu Ma, Donge Tang, Shaoyun Zhong, Xiaofang Yuan, Fengping Zheng, Zhipeng Zeng, Yumei Chen, Dongzhou Liu, Xiaoping Hong, Weier Dai, Lianghong Yin, Yong Dai   +13 more
doaj   +1 more source

Plasma Oxylipins and Their Precursors Are Strongly Associated with COVID-19 Severity and with Immune Response Markers

Metabolites, 2022
COVID-19 is characterised by a dysregulated immune response, that involves signalling lipids acting as mediators of the inflammatory process along the innate and adaptive phases.
Naama Karu, Alida Kindt, Lieke Lamont, Adriaan J. van Gammeren, Anton A. M. Ermens, Amy C. Harms, Lutzen Portengen, Roel C. H. Vermeulen, Willem A. Dik, Anton W. Langerak, Vincent H. J. van der Velden, Thomas Hankemeier   +11 more
doaj   +1 more source

Oxylipins as Potential Regulators of Inflammatory Conditions of Human Lactation

Metabolites, 2022
Chronic low-grade inflammation can be associated with obesity or subclinical mastitis (SCM), which is associated with poor infant growth in low- to middle-income country settings.
Rachel E. Walker
doaj   +1 more source

De Novo Transcriptome Assembly and Gene Expression Profiling of the Copepod Calanus helgolandicus Feeding on the PUA-Producing Diatom Skeletonema marinoi

Marine Drugs, 2020
Diatoms are the dominant component of the marine phytoplankton. Several diatoms produce secondary metabolites, namely oxylipins, with teratogenic effects on their main predators, crustacean copepods.
Sneha Asai, Remo Sanges, Chiara Lauritano, Penelope K. Lindeque, Francesco Esposito, Adrianna Ianora, Ylenia Carotenuto   +6 more
doaj   +1 more source

The Synthesis of Pentyl Leaf Volatiles and Their Role in Resistance to Anthracnose Leaf Blight

Frontiers in Plant Science, 2021
Volatiles are important airborne chemical messengers that facilitate plant adaptation to a variety of environmental challenges. Lipoxygenases (LOXs) produce a bouquet of non-volatile and volatile oxylipins, including C6 green leaf volatiles (GLVs), which
Zachary Gorman, Jordan P. Tolley, Jordan P. Tolley, Hisashi Koiwa, Michael V. Kolomiets   +4 more
doaj   +1 more source

The wound-activated ERF15 transcription factor drives Marchantia polymorpha regeneration by activating an oxylipin biosynthesis feedback loop

, 2022
The regenerative potential in response to wounding varies widely among species. Within the plant lineage, the liverwort Marchantia polymorpha displays an extraordinary regeneration capacity.
Vandendriessche, Wiske, Goeminne, Geert, Canher, Balkan, Xiang, Yanli, De Veylder, Lieven, Heyman, Jefri, Liang, Yuanke   +6 more
core   +1 more source

The Partitioning of Newly Assimilated Linoleic and α-Linolenic Acids Between Synthesis of Longer-Chain Polyunsaturated Fatty Acids and Hydroxyoctadecaenoic Acids Is a Putative Branch Point in T-Cell Essential Fatty Acid Metabolism

Frontiers in Immunology, 2021
Longer-chain polyunsaturated fatty acids (LCPUFAs) ≥20 carbons long are required for leukocyte function. These can be obtained from the diet, but there is some evidence that leukocytes can convert essential fatty acids (EFAs) into LCPUFAs. We used stable
Johanna von Gerichten, Annette L. West, Nicola A. Irvine, Elizabeth A. Miles, Philip C. Calder, Philip C. Calder, Karen A. Lillycrop, Barbara A. Fielding, Graham C. Burdge   +8 more
doaj   +1 more source

Oxylipin Signaling and Plant Growth

, 2010
Oxylipins are derived from the oxidation of polyunsaturated fatty acids. Further conversion of the resulting fatty acid hydroperoxides gives rise to a multitude of oxylipin classes, including hydroxy-, oxo-, or keto fatty acids, volatile aldehydes, and ...
Heilmann, Ingo, Munnik, Teun, Mosblech, Alina, Feussner, Ivo   +3 more
core   +1 more source

Fusarium verticillioides and maize interaction in vitro: Relationship between oxylipin cross-talk and fumonisin synthesis

, 2013
Fusarium verticillioides is one of the most important fungal pathogens to cause ear and stalk rot in maize, even if frequently asymptomatic, producing the harmful series of compounds named fumonisins.
V. Scala, E. Camera, P. Giorni, DALL'ASTA, Chiara, P. Battilani, M. Ludovici, CIRLINI, Martina, M. Reverberi   +7 more
core   +2 more sources

Epoxy-Oxylipins and Soluble Epoxide Hydrolase Metabolic Pathway as Targets for NSAID-Induced Gastroenteropathy and Inflammation-Associated Carcinogenesis

Frontiers in Pharmacology, 2019
Polyunsaturated fatty acids (PUFAs) including epoxide-modified ω-3 and ω-6 fatty acids are made via oxidation to create highly polarized carbon-oxygen bonds crucial to their function as signaling molecules.
Ryan D. Jones, Jie Liao, Xin Tong, Dandan Xu, Leyu Sun, Haonan Li, Guang-Yu Yang   +6 more
doaj   +1 more source