Results 21 to 30 of about 6,801 (211)

Crystalline silica-induced proinflammatory eicosanoid storm in novel alveolar macrophage model quelled by docosahexaenoic acid supplementation

Frontiers in Immunology, 2023
IntroductionPhagocytosis of inhaled crystalline silica (cSiO2) particles by tissue-resident alveolar macrophages (AMs) initiates generation of proinflammatory eicosanoids derived from the ω-6 polyunsaturated fatty acid (PUFA) arachidonic acid (ARA) that ...
Olivia K. Favor, Olivia K. Favor, Lichchavi D. Rajasinghe, Lichchavi D. Rajasinghe, Kathryn A. Wierenga, Kathryn A. Wierenga, Krishna R. Maddipati, Kin Sing Stephen Lee, Kin Sing Stephen Lee, Kin Sing Stephen Lee, Andrew J. Olive, James J. Pestka, James J. Pestka, James J. Pestka   +13 more
doaj   +1 more source

Metabolites milk oxylipin data

, 2022
Data used to assess quality of milk oxylipin measurements.
Rachel Walker (8114318)
core   +1 more source

Detoxification Cytochrome P450s (CYPs) in Families 1–3 Produce Functional Oxylipins from Polyunsaturated Fatty Acids

Cells, 2022
This manuscript reviews the CYP-mediated production of oxylipins and the current known function of these diverse set of oxylipins with emphasis on the detoxification CYPs in families 1–3.
Jazmine A. Eccles, William S. Baldwin
doaj   +1 more source

Oxylipins From Different Pathways Trigger Mitochondrial Stress Signaling Through Respiratory Complex III

Frontiers in Plant Science, 2021
Plant oxylipins are signaling molecules produced from fatty acids by oxidative pathways, mainly initiated by 9- and 13-lipoxygenases (9-LOX and 13-LOX), alpha-dioxygenases or non-enzymatic oxidation.
Yovanny Izquierdo, Luis Muñiz, Jorge Vicente, Jorge Vicente, Satish Kulasekaran, Verónica Aguilera, Ana López Sánchez, Ada Martínez-Ayala, Bran López, Tomás Cascón, Carmen Castresana   +10 more
doaj   +1 more source

Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks

International audienceOxylipins are major immunomodulating mediators, yet studies of inflammation focus mainly on cytokines. Here, using a standardized whole-blood stimulation system, we characterized the oxylipin-driven inflammatory responses to various
Kampschulte, Nadja, Bilek, Nicole, Mainka, Malwina, Chanson, Aurélie, Schebb, Nils, Helge, Quintana-Murci, Lluis, Villain, Etienne, Le Faouder, Pauline, Brandolini, Marion, Charbit, Bruno, Duffy, Darragh, Gladine, Cécile, Scriba, Thomas, J, Bertrand-Michel, Justine, Musvosvi, Munyaradzi   +14 more
core   +5 more sources

Therapeutic Potential of Plant Oxylipins

International Journal of Molecular Sciences, 2022
For immobile plants, the main means of protection against adverse environmental factors is the biosynthesis of various secondary (specialized) metabolites. The extreme diversity and high biological activity of these metabolites determine the researchers’ interest in plants as a source of therapeutic agents.
Tatyana Savchenko, Evgeny Degtyaryov, Yaroslav Radzyukevich, Vlada Buryak   +3 more
openaire   +2 more sources

Metabolic change of oxylipin pathway in cold responses of chickpea plants [PDF]

مجله بیوتکنولوژی کشاورزی, 2016
Oxylipins the products of fatty acid oxidation, to acclimate biotic and abiotic stresses. In this study, we evaluate the effects of cold stress by measuring manlodialdehyde (as membrane damage index), the activity of lipoxygenase (LOX) and allene oxide ...
Reza Maali Amiri, Behzad Sadeq Zadeh, Yad Allah Farayedi   +2 more
doaj   +1 more source

Deciphering OPDA Signaling Components in the Momilactone-Producing Moss Calohypnum plumiforme

Frontiers in Plant Science, 2021
Jasmonic acid (JA) and its biologically active form jasmonoyl-L-isoleucine (JA-Ile) regulate defense responses to various environmental stresses and developmental processes in plants.
Hideo Inagaki, Koji Miyamoto, Koji Miyamoto, Noriko Ando, Kohei Murakami, Koki Sugisawa, Shion Morita, Emi Yumoto, Miyu Teruya, Kenichi Uchida, Kenichi Uchida, Kenichi Uchida, Nobuki Kato, Takuya Kaji, Yousuke Takaoka, Yuko Hojo, Tomonori Shinya, Ivan Galis, Akira Nozawa, Tatsuya Sawasaki, Hideaki Nojiri, Hideaki Nojiri, Minoru Ueda, Minoru Ueda, Kazunori Okada   +24 more
doaj   +1 more source

Soluble Epoxide Hydrolase Derived Linoleic Acid Oxylipins, Small Vessel Disease Markers, and Neurodegeneration in Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Cerebral small vessel disease is associated with higher ratios of soluble‐epoxide hydrolase derived linoleic acid diols (12,13‐dihydroxyoctadecenoic acid [DiHOME] and 9,10‐DiHOME) to their parent epoxides (12(13)‐epoxyoctadecenoic acid [EpOME] 
Di Yu, Nuanyi Liang, Julia Zebarth, Qing Shen, Miracle Ozzoude, Maged Goubran, Jennifer S. Rabin, Joel Ramirez, Christopher J. M. Scott, Fuqiang Gao, Robert Bartha, Sean Symons, Seyyed Mohammad Hassan Haddad, Courtney Berezuk, Brian Tan, Donna Kwan, Robert A. Hegele, Allison A. Dilliott, Nuwan D. Nanayakkara, Malcolm A. Binns, Derek Beaton, Stephen R. Arnott, Jane M. Lawrence‐Dewar, Ayman Hassan, Dar Dowlatshahi, Jennifer Mandzia, Demetrios Sahlas, Leanne Casaubon, Gustavo Saposnik, Yurika Otoki, Krista L. Lanctôt, Mario Masellis, Sandra E. Black, Richard H. Swartz, Ameer Y. Taha, Walter Swardfager   +35 more
doaj   +1 more source

Fungal G-Protein-Coupled Receptors: A Promising Mediator of the Impact of Extracellular Signals on Biosynthesis of Ochratoxin A

Frontiers in Microbiology, 2021
G-protein-coupled receptors (GPCRs) are transmembrane receptors involved in transducing signals from the external environment inside the cell, which enables fungi to coordinate cell transport, metabolism, and growth to promote their survival ...
Jing Gao, Xinge Xu, Kunlun Huang, Zhihong Liang, Zhihong Liang   +4 more
doaj   +1 more source