Frontiers in Immunology, 2021 Longer-chain polyunsaturated fatty acids (LCPUFAs) ≥20 carbons long are required for leukocyte function. These can be obtained from the diet, but there is some evidence that leukocytes can convert essential fatty acids (EFAs) into LCPUFAs. We used stable
Johanna von Gerichten +8 more
doaj +1 more source
Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid metabolism act inversely on tumor progression. [PDF]
, 2020 The Western diet contains a high ratio of omega-6 (ω6) to omega-3 (ω3) polyunsaturated fatty acids (PUFA). The prototypical aryl hydrocarbon receptor (AHR) ligand, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), induces CYP1 family enzymes, which can ...
Hammock, Bruce D +5 more
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Oxylipin biosynthesis genes positively regulate programmed cell death during compatible infections with the synergistic pair potato virus x-potato virus Y and tomato spotted wilt virus [PDF]
, 2013 15 p.-11 fig.One of the most severe symptoms caused by compatible plant-virus interactions is systemic necrosis, which shares common attributes with the hypersensitive response to incompatible pathogens.
Aguilar, Emmanuel +4 more
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Role of Jasmonic Acid Pathway in Tomato Plant-Pseudomonas syringae Interaction [PDF]
, 2020 The jasmonic acid pathway has been considered as the backbone of the response against necrotrophic pathogens. However, a hemi-biotrophic pathogen, such as Pseudomonas syringae, has taken advantage of the crosstalk between the different plant hormones in ...
García Agustín, Pilar +3 more
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Frontiers in Pharmacology, 2019 Polyunsaturated fatty acids (PUFAs) including epoxide-modified ω-3 and ω-6 fatty acids are made via oxidation to create highly polarized carbon-oxygen bonds crucial to their function as signaling molecules.
Ryan D. Jones +6 more
doaj +1 more source
Multifunctional Enzymes in Oxylipin Metabolism
ChemBioChem, 2008 Fingers in lots of pies: For the first time a member of the CYP74 enzyme subfamily (9‐AOS) from tomato has been shown by chemical and analytical approaches to catalyze multiple reactions. These multifunctional properties of 9‐AOS from the oxylipin‐forming lipoxygenase (LOX) pathway raise several new questions on lipid‐derived signaling.
Wasternack, Claus, Feussner, Ivo
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Effects of hemodialysis on plasma oxylipins [PDF]
Physiological Reports, 2020 Chronic kidney disease (CKD) is an important risk factor for cardiovascular and all-cause mortality. Survival rates among end-stage renal disease (ESRD) hemodialysis patients are poor and most deaths are related to cardiovascular disease. Oxylipins constitute a family of oxygenated natural products, formed from fatty acid by pathways involving at least
Benjamin Gollasch +5 more
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The emerging role of oxylipins in thrombosis and diabetes. [PDF]
, 2014 The prevalence of cardiovascular disease (CVD), the leading cause of death in the US, is predicted to increase due to the shift in age of the general population and increase in CVD risk factors such as obesity and diabetes.
Ahmed, Intekhab +2 more
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Types and Distribution of Bioactive Polyunsaturated Aldehydes in a Gradient from Mesotrophic to OligotrophicWaters in the Alborán Sea (Western Mediterranean) [PDF]
, 2020 Polyunsaturated aldehydes (PUAs) are bioactive molecules suggested as chemical defenses and infochemicals. In marine coastal habitats, diatoms reach high PUA production levels during bloom episodes.
Bartual Magro, Ana +11 more
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CYP450-derived oxylipins mediate inflammatory resolution [PDF]
Proceedings of the National Academy of Sciences, 2016 Significance A number of lipid mediators are known to contribute to inflammatory resolution. Fatty acid metabolites of cytochrome P450 (CYP) enzymes are found in abundance; however, their roles in inflammatory resolution are not known.
Derek W. Gilroy +8 more
openaire +4 more sources