Results 41 to 50 of about 461,399 (248)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Possible relació entre el consum de lactis i la mutació d'un gen cancerigen [PDF]

, 2007
Un article científic publicat al número de juliol de la revista anglesa Journal of Epidemiology and Community Health suggereix que pot existir una relació entre la ingesta de productes lactis i l'aparició de mutacions en un gen important al càncer de ...
Porta, Miquel,
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

In Vitro Lipid Overload Affects Cellular Proliferation, Apoptosis, and Senescence in a Time-Dependent Manner in HepG2 Hepatocytes and LX-2 Hepatic Stellate Cells

Cells
Different cellular mechanisms influence steatotic liver disease (SLD) progression. The influence of different levels of steatogenic inputs has not been studied in hepatocytes and hepatic stellate cells (HSCs).
Adriana Campos-Espinosa, Carolina Guzmán, Karla Zaira Medina-Ávila, Gabriela Gutierrez-Reyes   +3 more
doaj   +1 more source

A propósito de un caso : paciente con cuadro de disartria de una hora y media de evolución [PDF]

, 2017
Insulinoma is a neoplasia of pancreatic β-cells that secretes insulin. It constitutes a rare cause of hypoglycemia. Poor knowledge of this disease is explained by the low incidence, 4 in 1 million people per year. The nonspecific symptoms and its size
Roldán Vásquez, Ana María
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Imagen ecográfica de la obstrucción biliar extrahepática en el perro : descripción de 7 casos [PDF]

, 1995
Se realizó un estudio ecográfico en siete perros que presentaban un cuadro de ictericia por obstrucción biliar extrahepática. Esta técnica permitió llegar al diagnóstico en seis de los casos.
Díez Bru, N., Fermín, M. L., García Real, I., Llorens, P., Rollán, E., Toni, P.   +5 more
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Collagen matrix scaffold as vehicle of WP1066, STAT-3 inhibitors, in an in vitro hepatocellular model.

Annals of Hepatology
Introduction and objectives: Liver disease causes approximately 1.75 million deaths per year and chronic liver disease (CLD) and is usually detected in advanced stages (cirrhosis or hepatocellular carcinoma) that require partial ablation or transplant ...
Moises Martinez-Castillo, Cristina Piña-Barba, Israel A. Núñez-Tapia, Marisela Hernandez-Santillan, Abigail Hernández-Barragán, Gabriela Gutiérrez-Reyes   +5 more
doaj   +1 more source

Multiple endocrine neoplasia type 1 in a patient diagnosed with nesidioblastosis. A case presentation

Medisur, 2023
Multiple endocrine neoplasias encompass a series of syndromes characterized by their genetic origin and the involvement of one or more glands. A 23-years-old male patient with a health history of nesidioblastosis diagnosed at 16 years of age, who ...
Olivia Elizabeth Altamirano Guerrero, María Gabriela Balarezo García, Juan Sebastián Lima Icaza   +2 more
doaj