Results 41 to 50 of about 466,613 (249)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
EFECTO DE LA INDOMETACINA SOBRE LA INCIDENCIA DE PANCREATITIS POST-CPRE COMPARADO CON PLACEBO EN EL CENTRO MÉDICO LIC. ADOLFO LÓPEZ MATEOS: ENSAYO CLÍNICO DOBLE CIEGO ALEATORIZADO [PDF]
, 2016 1. RESUMEN. INTRODUCCION: La pancreatitis es la complicación más común causada por la CPRE, que incrementa la estancia hospitalaria y el costo per cápita.
CASTILLO ESPINOSA, DULCE MARIA +1 more
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
CellsDifferent cellular mechanisms influence steatotic liver disease (SLD) progression. The influence of different levels of steatogenic inputs has not been studied in hepatocytes and hepatic stellate cells (HSCs).
Adriana Campos-Espinosa +3 more
doaj +1 more source
Hemoperitoneo espontáneo secundario a rotura de pseudoquiste pancreático: una causa inusual de muerte inesperada [PDF]
, 2015 Presentamos un caso de fallecimiento por hemoperitoneo masivo espontáneo como complicación tardía de un pseudoquiste pancreático de evolución tórpida. Se trata de una causa muy infrecuente de hemoperitoneo espontáneo en la literatura médica. Se describen
Aguilera Tapia, Beatriz +1 more
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Imagen ecográfica de la obstrucción biliar extrahepática en el perro : descripción de 7 casos [PDF]
, 1995 Se realizó un estudio ecográfico en siete perros que presentaban un cuadro de ictericia por obstrucción biliar extrahepática. Esta técnica permitió llegar al diagnóstico en seis de los casos.
Díez Bru, N. +5 more
core
Early feeding to modify digestive enzyme activity in broiler chickens [PDF]
, 2014 Objective. To evaluate the effect on digestive enzyme activity in broiler chickens by providing food in the first 48 hrs. after birth. Materials and methods.
Emma Rueda de A. +3 more
core +3 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Annals of HepatologyIntroduction and objectives: Liver disease causes approximately 1.75 million deaths per year and chronic liver disease (CLD) and is usually detected in advanced stages (cirrhosis or hepatocellular carcinoma) that require partial ablation or transplant ...
Moises Martinez-Castillo +5 more
doaj +1 more source