Results 71 to 80 of about 461,399 (248)
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Estudio PET-TC con 18F-fluoro-L-DOPA combinado con el análisis genético para la optimización de la clasificación y tratamiento de un niño con hiperinsulinismo congénito grave [PDF]
BACKGROUND: Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycaemia in infancy. The differential diagnosis between focal and diffuse forms of CHI is of great importance when planning surgery. The aim of this article is to
Arbizu, J. (Javier) +6 more
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Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
La ruta de señalización WNT en la determinación de progenitores pancreáticos [PDF]
1 página. IX Jornadas Andaluzas Salud Investiga. Cádiz 20-22 octubre, 2010.Nuestro laboratorio trata de determinar los mecanismos moleculares implicados en la formación de los distintos tipos celulares pancreáticos adultos a partir de células ...
Cano González, David A. +2 more
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Páncreas heterotópico como causa de intususcepción y sangrado gastrointestinal, reporte de caso
Introducción: la intususcepción es el deslizamiento de un segmento intestinal hacia dentro de uno adyacente, lo que provoca obstrucción, inflamación e isquemia. En adultos, representa el 5% de los casos de invaginación, lo que supone entre el 1% y el 5%
Valentina Patiño Pérez +1 more
doaj +1 more source
Titulación: Grao en Farmacia -- Materia: Anatomía, Histoloxía e CitoloxíaO aparato dixestivo é o encargado de transformar os alimentos que inxerimos en sustancias máis sinxelas e facilmente asimilables polo organismo.
Rodríguez Pérez, Ana Isabel
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Aberrant spleen simulating an adrenal mass [PDF]
Indexación: Web of Science; ScieloIntroducción: El diagnóstico de los así llamados "incidentalomas" suprarrenales, cada vez más frecuente en la práctica clínica, plantea un diagnóstico diferencial importante.
Castillo C., Octavio A., Pizzi L., Pablo
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cirugía laparoscópica hepática y pancreática [PDF]
The development of laparoscopic surgery also includes the more complex procedures of abdominal surgery such as those that affect the liver and the pancreas.
Marti-Cruchaga, P. (Pablo) +6 more
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