Results 161 to 170 of about 37,984 (216)

Case Report: Fatal pneumonitis caused by Camrelizumab and Erlotinib in a patient with metastatic pancreatic cancer. [PDF]

Front Oncol
Jiang Y, Ma L, Lu B, Tian W.
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Ensemble deep learning model based on CT scans: differentiating and subtype-classifying pancreatic inflammations and tumors, and predicting pancreatic lesion invasiveness. [PDF]

Quant Imaging Med Surg
Pan X, Yang Q, Shi M, He Y, Qin K, Zhu J, Zhang T, Wu H, Du R, Sun M, Chen S, Yang H, Fang Y, Zhang S, Yang B.   +14 more
europepmc   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Validation of a Pretrained Artificial Intelligence Model for Pancreatic Cancer Detection on Diagnosis and Prediagnosis Computed Tomography Scans. [PDF]

Invest Radiol
Degand L, Abi-Nader C, Bône A, Vetil R, Placido D, Chmura P, Rohé MM, De Masi F, Brunak S.   +8 more
europepmc   +1 more source

Cadaveric addendum to the consensus on ultrasound‐based lymph‐node staging in gynecological cancer

Ultrasound in Obstetrics &Gynecology, EarlyView.
D. Fischerova, E. Farsi, E. Facchetti, E. Panizzolo, G. Gambino, H. Reina, F. Sousa, M. R. Kadajari, N. Tiszlavicz, G. Garganese, O. Nanka, Collaborators, E. Gatti, C. Culcasi   +13 more
wiley   +1 more source

Integrated Engineering of CAR‐T Cells for Solid Tumours

Cell Proliferation, EarlyView.
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang, Tan Li, Ping He, Zhijie Zhao, Shenglong Li, Liming Wang   +5 more
wiley   +1 more source

Designing a national network of pancreas units: the Italian model for high-quality pancreatic cancer care. [PDF]

Updates Surg
Alfieri S, Quero G, Tondolo V, Balzano G, Cardone A, Conzo G, Fabbri C, Ferrari V, Frulloni L, Gruttadauria S, Ianelli E, Maiello E, Menghi R, Milella M, Reni M, Salvia R, Spada C, De Bella MT, Tarantino I, Tortora G, Valsecchi F, Vincenti L, Vistoli F, Boggi U.   +23 more
europepmc   +1 more source

A Comprehensive Comparative Analysis of Sequence‐Based Deep Learning Models for Single‐Cell Genomics

Cell Proliferation, EarlyView.
To streamline the application of sequence‐based DL methods in single‐cell genomics, we established a two‐layer CNN as our baseline model. We focus our benchmark on how data characteristics, hyperparameter optimization, and advanced model architectures impact performance across sequence‐to‐expression and sequence‐to‐regulation tasks.
Guoxia Wen, Jiaqi Li, Hanyu Wu, Jialing Fang, Yuting Fu, Mengmeng Jiang, Yuqing Mei, Rui Xu, Yuxuan Du, Siran Chu, Guoji Guo, Xiaoping Han, Jingjing Wang   +12 more
wiley   +1 more source