Results 171 to 180 of about 34,845 (214)

Clinical Applications of Phosphoproteomics: Illuminating Cancer Signaling and Enabling Rational Therapeutic Strategies

Cancer Science, EarlyView.
Mass spectrometry‐based phosphoproteomics for mechanistic dissection of cancer signaling pathways and uncovering therapeutic vulnerabilities. ABSTRACT Protein phosphorylation is a central post‐translational modification regulating cellular signaling, frequently dysregulated in cancer.
Hirokazu Shoji, Narikazu Boku, Jun Adachi   +2 more
wiley   +1 more source

Characteristics, Prognosis and Reasons for Opting-Out of Treatment in Patients with Untreated Pancreatic Cancer. [PDF]

Curr Oncol
Ladekarl M, Stender MT.
europepmc   +1 more source

Validation of Digital Cytology for Primary Diagnosis Across a Range of Specimen Types

Cytopathology, EarlyView.
This single‐centre validation study demonstrated strong diagnostic concordance between high‐resolution whole‐slide imaging and traditional light microscopy across diverse cytology specimen types. Even with limited prior experience, pathologists found digital cytology feasible and acceptable for diagnostic use.
Talisa Mistry, Harriet Hunter, Dahmane Oukrif, Sabine Pomplun, Reena Khiroya, Mary Falzon, Tanya Alan, Manuel Rodriguez‐Justo, Adam P. Levine   +8 more
wiley   +1 more source

Radiomics in sporadic microsatellite instable, mismatch repair deficient and Lynch syndrome-associated pancreatic ductal adenocarcinoma: a pilot study. [PDF]

Front Oncol
Eikenboom EL, Magnin J, Alessandris R, Horvat N, Gonen M, Jarnagin WR, Drebin J, D'Angelica MI, Kingham TP, Balachandran VP, Soares KC, Wagner A, Spaander MCW, Chakraborty J, Wei AC.   +14 more
europepmc   +1 more source

Cadaveric addendum to the consensus on ultrasound‐based lymph‐node staging in gynecological cancer

Ultrasound in Obstetrics &Gynecology, EarlyView.
D. Fischerova, E. Farsi, E. Facchetti, E. Panizzolo, G. Gambino, H. Reina, F. Sousa, M. R. Kadajari, N. Tiszlavicz, G. Garganese, O. Nanka, Collaborators, E. Gatti, C. Culcasi   +13 more
wiley   +1 more source

Banting memorial lecture 2025: Aligning clinical practice, policy and research

Diabetic Medicine, EarlyView.
Abstract National clinical leadership, on a background of clinical practice and clinical research, provides unique perspectives. I have focused the Banting Memorial Lecture 2025 on the implementation of national programmes across England since 2013, for which, along with colleagues at NHS England, I successfully made the case for investment, led the ...
Jonathan Valabhji
wiley   +1 more source

From radiomics to transformers in pancreatic cancer detection and prognosis. [PDF]

Front Med (Lausanne)
Almufareh MF, Tehsin S, Humayun M, Kausar S, Farooq A, Aldossary H, Aljohani A.   +6 more
europepmc   +1 more source

Providing holistic care for patients with metabolic dysfunction‐associated steatotic liver disease/metabolic dysfunction‐associated steatohepatitis: Key aspects of clinical assessment and how to develop individualised care plans for surveillance and interventions

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD), characterised by hepatic steatosis and metabolic dysfunction (i.e., obesity, type 2 diabetes, dyslipidaemia, and hypertension), is affecting over 30% of the adult population worldwide.
Lanlan Chen, Paul Horn, Frank Tacke
wiley   +1 more source