Results 211 to 220 of about 26,428 (238)
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THE PHOTOPHYSICS OF p‐AMINOBENZOIC ACID
Photochemistry and Photobiology, 1995Abstract— The lowest‐lying allowed UV transition in p‐aminobenzoic acid (PABA) is assigned Γ→1La based on quantitative absorption and fluorescence studies, as well as semiempirical PM3 multielec‐tron configuration interaction calculations. The oscillator strengths, fluorescence quantum efficiencies and lifetimes are reported for PABA in several polar,
Bala R. Ramachandran, Arthur M. Halpern
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Propanal hydroamination with p-aminobenzoic acid [PDF]
The propanal hydroamination was studied. It was found that the reaction in ethanol proceeded faster than in 2-propanol. By 1H and 13C NMR method the existence was proved of a tautomeric equilibrium in ethanol solution between 4-(propylideneamino)benzoic acid and its enamine form, 4-(prop-1-en-1-ylamino)benzoic acid.
Matvey S. Gruzdev+3 more
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p-Aminobenzoic acid as a stimulator of angiogenesis
Bulletin of Experimental Biology and Medicine, 1996p-Aminobenzoic acid (0.002 and 0.005% in a volume of 0.1 ml) stimulates angiogenesis in the yolk sac of chick embryos. It is more effective in a concentration of 0.005%, significantly increasing the length and branching of large vessels (by 27–33% and 35–43%, respectively) in comparison with the control (injection of 0.1 ml normal saline).
A A Sologub+5 more
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Acetylation of p-aminobenzoic acid by human blood
Biochemical Pharmacology, 1981Abstract Acetylation of p -aminobenzoic acid was studied in human blood cell lysates. The rate of acetylation with acetyl-coenzyme A was 3.4 nmoles per min per 0.5 ml lysate (corresponding to 0.5 ml blood with a 50% hematocrit). In the presence of a coenzyme A generating system, the rate was only 0.1 nmole per min per 0.5 ml lysate.
S.H. Blondheim+1 more
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Photocontact Dermatitis from P-Aminobenzoic Acid
Dermatology, 1978A 6-year-old girl with xeroderma pigmentosum was contact and photocontact sensitized to PABA which had been used as a sunscreening agent. The activating wavelengths for photocontact dermatitis were in long-wave ultraviolet light. The experimental photocontact sensitization was not induced in guinea pigs. Although PABA is the most effective and harmless
Takeshi Horio, Takako Higuchi
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p–Aminobenzoic acid derivatives as acetylcholinesterase inhibitors
European Journal of Medicinal Chemistry, 2005Because Alzheimer's disease (AD) is a medical problem characterized by progressive loss of memory and cognition that is associated with a deficient cholinergic system, this work aims to evaluate some p-aminobenzoic acid (PABA) derivatives as acetylcholinesterase inhibitors in vitro, in continuation with our last studies.
Iván Vázquez Alcántara+3 more
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Journal of Drug Targeting, 1998
The aim of the present study was to evaluate the transfer of N-acetyl-p-aminobenzoic acid (AcPABA) across the rat term placenta and the rat small intestine and to compare it with that of its parent drug p-aminobenzoic acid (PABA). Umbilical perfusion of the rat term placenta was used to determine the materno-fetal transfer. AcPABA appeared in the fetal
O. Jindrová+4 more
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The aim of the present study was to evaluate the transfer of N-acetyl-p-aminobenzoic acid (AcPABA) across the rat term placenta and the rat small intestine and to compare it with that of its parent drug p-aminobenzoic acid (PABA). Umbilical perfusion of the rat term placenta was used to determine the materno-fetal transfer. AcPABA appeared in the fetal
O. Jindrová+4 more
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Drug Evolution: p-Aminobenzoic Acid as a Building Block
Current Medicinal Chemistry, 2002The core or the building block is an important component in drug development. In this article, we propose and review p-aminobenzoic acid (PABA) as a building block used in the design of drugs or drug candidates. PABA is frequently found as a structure moiety in drugs. For example, in a database of 12,111 commercial drugs, 1.5% (184 drugs) were found to
Kluczyk, Alicja+6 more
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Journal of Pharmaceutical and Biomedical Analysis, 2007
p-Aminobenzoic acid (PABA) and its metabolites (p-aminohippuric acid, p-acetamidobenzoic acid, and p-acetamidohippuric acid) were detected using high-performance liquid chromatography with an electrochemical (carbon paste) detector (HPLC-ECD). For direct current (dc) mode, with the current at a constant potential, and measurements with suitable ...
Lai-Hao Wang+2 more
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p-Aminobenzoic acid (PABA) and its metabolites (p-aminohippuric acid, p-acetamidobenzoic acid, and p-acetamidohippuric acid) were detected using high-performance liquid chromatography with an electrochemical (carbon paste) detector (HPLC-ECD). For direct current (dc) mode, with the current at a constant potential, and measurements with suitable ...
Lai-Hao Wang+2 more
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