Results 91 to 100 of about 19,039,568 (311)

Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling

open access: yesMolecular Cancer, 2006
Background Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are bioactive lipid signaling molecules implicated in tumor dissemination.
Anthis Nicholas J   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

THE SPECTRUM OF RANDOM INNER-PRODUCT KERNEL MATRICES

open access: yes, 2013
We consider nxn matrices whose (i, j)th entry is f(X-i(T) X-j), where X-1,..., X-n are i.i.d. standard Gaussian in R-p, and f is a real-valued function. The weak limit of the eigenvalue distribution of these random matrices is studied at the limit when p,
Cheng, Xiuyuan, Singer, Amit
core   +1 more source

On Some Matrix Trace Inequalities

open access: yesJournal of Inequalities and Applications, 2010
We first present an inequality for the Frobenius norm of the Hadamard product of two any square matrices and positive semidefinite matrices. Then, we obtain a trace inequality for products of two positive semidefinite block matrices by using block ...
Ulukök Zübeyde   +1 more
doaj  

MULTIPLICATIVE PRINCIPAL-MINOR INEQUALITIES FOR TRIDIAGONAL SIGN-SYMMETRIC P-MATRICES

open access: yesTaiwanese Journal of Mathematics, 2001
Three classes of matrices (positive definite, invertible totally nonnegative, and \(M\)-matrices) are considered and the problem is studied which of the ratios of products of principal minors are bounded over all matrices in the given class. This problem is solved for the class of tridiagonal sign-symmetric \(P\)-matrices.
Fallat, Shaun M., Johnson, Charles R.
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Universality of some models of random matrices and random processes

open access: yes, 2012
Naumov A. Universality of some models of random matrices and random processes.
Naumov, Alexey
core  

A simple procedure for the comparison of covariance matrices

open access: yesBMC Evolutionary Biology, 2012
Background Comparing the covariation patterns of populations or species is a basic step in the evolutionary analysis of quantitative traits. Here I propose a new, simple method to make this comparison in two population samples that is based on comparing ...
Garcia Carlos
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

RAxML-matrices

open access: yes, 2019
The file contains the nine .phy formatted data matrices for use in RAxML to construct the phylogenomic trees. The nine matrices were generated using ipyrad.
Amanda Haponski (6270641)   +2 more
core   +1 more source

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