Results 111 to 120 of about 1,604,213 (297)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

The extracellular matrix protects P seudomonas aeruginosa biofilms by limiting the penetration of tobramycin

, 2013
Boo Shan Tseng, Wei Zhang, Joe J. Harrison, Tam P. Quach, Jisun L. Song, Jon Penterman, Pradeep K. Singh, David L. Chopp, Aaron I. Packman, Matthew R. Parsek   +9 more
openalex   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Deep hypergraph regularized $$L_{p}$$ L p smooth semi-nonnegative matrix factorization for hierarchical clustering analysis

Journal of King Saud University: Computer and Information Sciences
In recent years, deep matrix factorization (DMF) has garnered significant attention for its effectiveness in various artificial intelligence applications.
Shunli Li, Ling Wang, Mingjun Bai
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Matrix metalloproteinase-8 and substance P levels in root canal exudates of nonvital teeth

, 2011
Su‐Jung Shin, Woo‐Cheol Lee, Jae‐Il Lee, Seung‐Ho Baek, Kee‐Yeon Kum, Won‐Jun Shon, Kwang‐Shik Bae   +6 more
openalex   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The Role of Dislocation Type in the Thermal Stability of Cellular Structures in Additively Manufactured Austenitic Stainless Steel

Advanced Science
The ultrafine cellular structure promotes the extraordinary mechanical performance of metals manufactured by laser powder‐bed‐fusion (L‐PBF). An in‐depth understanding of the mechanisms governing the thermal stability of such structures is crucial for ...
Dayong An, Yao Xiao, Junshi Yu, Xu Zhang, Zan Li, Yan Ma, Rui Li, Xianhong Han, Xifeng Li, Jun Chen, Stefan Zaefferer   +10 more
doaj   +1 more source

Efficient Computation of a Canonical Form for a Generalized P-matrix

, 2012
We use recent results on algorithms for Markov decision problems to show that a canonical form for a generalized P-matrix can be computed, in some important cases, by a strongly polynomial algorithm.
openaire   +2 more sources