Results 41 to 50 of about 21,096,303 (314)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Advanced NanoBiomed ResearchUltrasound can activate nano/microparticles to induce reactive oxygen species (ROS). The advantages of deep penetration and precise spatiotemporal control are demonstrated for multiple applications, such as sonodynamic therapy, chemical industry, and ...
Yijun Han +8 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Application of Haddon’s matrix in qualitative research methodology: an experience in burns epidemiology [PDF]
Background: Little has been done to investigate the application of injury specific qualitative research methods in the field of burn injuries. The aim of this study was to use an analytical tool (Haddon’s matrix) through qualitative research methods to ...
عرشی, شهنام +4 more
core +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
, 2018 Matrix of 53 dental characters and 13 paromomyid ...
Sergi López-Torres (7061078) +1 more
core +3 more sources
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Advanced ScienceConstructing colloidal particles into designated hierarchies with integrated functionalities offers insights into bottom‐up material fabrication. However, the arbitrary and controllable assembly of individual nanoscale and microscale particles remains ...
Jie Zhao +12 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2020 Salivary gland hypofunction causes significant morbidity and loss of quality of life for head and neck cancer patients treated with radiotherapy. Preventing hypofunction is an unmet therapeutic need.
Isabelle M.A. Lombaert +17 more
doaj +1 more source
Matrix regularization of classical Nambu brackets and super p-branes
Journal of High Energy Physics, 2021 We present an explicit matrix algebra regularization of the algebra of volume-preserving diffeomorphisms of the n-torus. That is, we approximate the corresponding classical Nambu brackets using sl N n 2 ℂ $$ \mathfrak{sl}\left({N}^{\left\lceil \frac{n}{2}
Meer Ashwinkumar +2 more
doaj +1 more source