Results 41 to 50 of about 27,019,626 (261)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
On pseudospectra of matrix polynomials and their boundaries
, 2008 In the first part of this paper (Sections 2-4), the main concern is with the boundary of the pseudospectrum of a matrix polynomial and, particularly, with smoothness properties of the boundary.
Boulton, Lyonell; id_orcid +5 more
core +1 more source
Matrix regularization of classical Nambu brackets and super p-branes
Journal of High Energy Physics, 2021 We present an explicit matrix algebra regularization of the algebra of volume-preserving diffeomorphisms of the n-torus. That is, we approximate the corresponding classical Nambu brackets using sl N n 2 ℂ $$ \mathfrak{sl}\left({N}^{\left\lceil \frac{n}{2}
Meer Ashwinkumar +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Molecular Therapy: Methods & Clinical Development, 2020 Salivary gland hypofunction causes significant morbidity and loss of quality of life for head and neck cancer patients treated with radiotherapy. Preventing hypofunction is an unmet therapeutic need.
Isabelle M.A. Lombaert +17 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Point equation of the boundary of the numerical range of a matrix polynomial [PDF]
, 2002 The numerical range of an n×n matrix polynomialP(λ)=Amλm+Am−1λm−1+⋯+A1λ+A0is defined byW(P)=λ∈C:x*P(λ)x=0,x∈Cn,x≠0.For the linear pencil P(λ)=Iλ−A, the range W(P) coincides with the numerical range of matrix A, F(A)={x*Ax:x∈Cn,x*x=1}.
Chien, MT +5 more
core +1 more source
On Generalized p,q-Euler Matrix and Associated Sequence Spaces
Journal of Function Spaces, 2021 In this study, we introduce new BK-spaces bsr,tp,q and b∞r,tp,q derived by the domain of p,q-analogue Br,tp,q of the binomial matrix in the spaces ℓs and ℓ∞, respectively.
Taja Yaying +2 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source