Results 41 to 50 of about 30,659,002 (304)

A script to highlight hydrophobicity and charge on protein surfaces [PDF]

open access: yes, 2015
The composition of protein surfaces determines both affinity and specificity of protein-protein interactions. Matching of hydrophobic contacts and charged groups on both sites of the interface are crucial to ensure specificity.
Tania eMorán Luengo   +12 more
core   +2 more sources

CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway

open access: yesCancer Communications, 2023
Background As a rapid‐progressing tumor, breast malignant phyllodes tumors (PTs) are challenged by the lack of effective therapeutic strategies and suitable prognostic markers.
Jiewen Chen   +13 more
doaj   +1 more source

Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering [PDF]

open access: yes, 2012
Understanding the protein fitness landscape is important for describing how natural proteins evolve and for engineering new proteins with useful properties.
Romero, Philip Anthony
core   +1 more source

Intracellular Phosphorylation of the Sendal Virus P Protein

open access: yesVirology, 1995
Phosphorylation status of the Sendai virus P protein was examined during virus infection and compared with cell-free phosphorylation. P protein from Sendai virus-infected (VI) and P/C gene-transfected (PT) mammalian cells and from purified virions (PV) was phosphorylated at only serine residues.
Byrappa, Sridhar   +4 more
openaire   +2 more sources

Prediction of protein-protein interaction types using association rule based classification [PDF]

open access: yes, 2009
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Park et alBackground: Protein-protein interactions (PPI) can be classified according to their characteristics into, for example obligate or transient ...
José A Reyes   +14 more
core   +1 more source

Memory immune response: a major challenge in vaccination

open access: yesBiomolecular Concepts, 2012
A crucial challenge for vaccine development is to design vaccines that induce a long-lasting protective immune response, i.e., immune memory. The persistence of antigen-specific antibody titers over a protective threshold, and the ability to exibit a ...
Prisco Antonella   +1 more
doaj   +1 more source

The Venom of Ornithoctonus huwena affect the electrophysiological stability of neonatal rat ventricular myocytes by inhibiting sodium, potassium and calcium current

open access: yesChannels, 2018
Spider venoms are known to contain various toxins that are used as an effective means to capture their prey or to defend themselves against predators. An investigation of the properties of Ornithoctonus huwena (O.huwena) crude venom found that the venom ...
Sha Yan   +4 more
doaj   +1 more source

Naturally acquired immune responses to P. vivax merozoite surface protein 3α and merozoite surface protein 9 are associated with reduced risk of P. vivax malaria in young Papua New Guinean children [PDF]

open access: yes, 2013
Plasmodium vivax is the most geographically widespread human malaria parasite. Cohort studies in Papua New Guinea have identified a rapid onset of immunity against vivax-malaria in children living in highly endemic areas. Although numerous P.
Kiniboro, B   +36 more
core   +2 more sources

Non-dispersive phloem-protein bodies (NPBs) of Populus trichocarpa consist of a SEOR protein and do not respond to cell wounding and Ca2+ [PDF]

open access: yesPeerJ, 2018
Differentiating sieve elements in the phloem of angiosperms produce abundant phloem-specific proteins before their protein synthesis machinery is degraded.
Daniel L. Mullendore   +6 more
doaj   +2 more sources

Exploring Protein Sequence Space Using Computationally Directed Recombination [PDF]

open access: yes, 2006
Evolution has provided us with many protein sequences. However, these sequences represent a very small fraction of the possible sequences. In the laboratory, scientists have explored areas of sequence space not represented by natural proteins both to ...
Meyer, Michelle Margaret
core   +1 more source

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