Results 31 to 40 of about 24,345,005 (317)

CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway

open access: yesCancer Communications, 2023
Background As a rapid‐progressing tumor, breast malignant phyllodes tumors (PTs) are challenged by the lack of effective therapeutic strategies and suitable prognostic markers.
Jiewen Chen   +13 more
doaj   +1 more source

THU0061 Ribosomal p protein antibodies [PDF]

open access: yesAnnals of the Rheumatic Diseases, 2001
Background Circulating autoantibodies are one of the main characteristic of autoimmune disease as systemic lupus erythematosus (SLE). The associations between anti-DNA antibodies and renal disease, anti-Ro with cutaneous manifestations and congenital heart block are well established.
SM Ivanova   +4 more
openaire   +1 more source

Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering [PDF]

open access: yes, 2012
Understanding the protein fitness landscape is important for describing how natural proteins evolve and for engineering new proteins with useful properties.
Romero, Philip Anthony
core   +1 more source

Allergenic Ribosomal P Proteins [PDF]

open access: yesJournal of Clinical Microbiology and Biochemical Technology, 2017
Allergenic ribosomal P proteins have been isolated almost exclusively from allergenic mold species with the exception of one from almond.
openaire   +2 more sources

Studying protein-protein interactions using peptide arrays

open access: yes, 2010
Screening of arrays and libraries of compounds is well-established as a high-throughput method for detecting and analyzing interactions in both biological and chemical systems. Arrays and libraries can be composed from various types of molecules, ranging
Rito, T.   +7 more
core   +1 more source

Exploring Protein Sequence Space Using Computationally Directed Recombination [PDF]

open access: yes, 2006
Evolution has provided us with many protein sequences. However, these sequences represent a very small fraction of the possible sequences. In the laboratory, scientists have explored areas of sequence space not represented by natural proteins both to ...
Meyer, Michelle Margaret
core   +1 more source

CHAPTER 1.1. Disulfide Bonds in Protein Folding and Stability

open access: yes, 2018
Disulfide bonds are unique among post-translational modifications, as they add covalent crosslinks to the polypeptide chain. Accordingly, they can exert pronounced effects on protein folding and stability. This is of particular importance for secreted or
Sub Cellular Protein Chemistry   +7 more
core   +1 more source

Memory immune response: a major challenge in vaccination

open access: yesBiomolecular Concepts, 2012
A crucial challenge for vaccine development is to design vaccines that induce a long-lasting protective immune response, i.e., immune memory. The persistence of antigen-specific antibody titers over a protective threshold, and the ability to exibit a ...
Prisco Antonella   +1 more
doaj   +1 more source

Intracellular Phosphorylation of the Sendal Virus P Protein

open access: yesVirology, 1995
Phosphorylation status of the Sendai virus P protein was examined during virus infection and compared with cell-free phosphorylation. P protein from Sendai virus-infected (VI) and P/C gene-transfected (PT) mammalian cells and from purified virions (PV) was phosphorylated at only serine residues.
Byrappa, Sridhar   +4 more
openaire   +2 more sources

Non-dispersive phloem-protein bodies (NPBs) of Populus trichocarpa consist of a SEOR protein and do not respond to cell wounding and Ca2+ [PDF]

open access: yesPeerJ, 2018
Differentiating sieve elements in the phloem of angiosperms produce abundant phloem-specific proteins before their protein synthesis machinery is degraded.
Daniel L. Mullendore   +6 more
doaj   +2 more sources

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