Results 71 to 80 of about 3,946,788 (277)
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Dual Frobenius manifolds of minimal gravity on disk
Liouville field theory approach to 2-dimensional gravity possesses the duality (b ↔ b −1). The matrix counterpart of minimal gravity ℳ(q, p) (q < p co-prime) is effectively described on A q−1 Frobenius manifold, which may exhibit a similar duality p ↔ q,
Aditya Bawane +2 more
doaj +1 more source
Grothendieck's conjecture on p-curvatures predicts that an arithmetic differential equation has a full set of algebraic solutions if and only if its reduction in positive characteristic has a full set of rational solutions for almost all finite places ...
Di Vizio, Lucia
core +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Steklov problems for the p−Laplace operator involving Lq-norm
In this paper, we are concerned with the study of the spectrum for the nonlinear Steklov problem of the form {Δpu=|u|p-2uin Ω,|∇u|p-2∂u∂v=λ‖u‖q,∂Ωp-q|u|q-2uon ∂Ω,\left\{ {\matrix{{{\Delta _p}u = {{\left| u \right|}^{p - 2}}u} \hfill & {{\rm{in}}\,\Omega ,
Alaoui My Driss Morchid +2 more
doaj +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A definable (p,q)-theorem for NIP theories
Added section 4.1 about VC ...
openaire +2 more sources
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Noncritical String Field Theory for 2d Quantum Gravity Coupled to (p, q)-Conformal Fields [PDF]
We propose a noncritical string field theory for 2d quantum gravity coupled to (p, q) conformal fields. The Hamiltonian is described by the generators of the Wp algebra, and the Schwinger–Dyson equation is equivalent to a vacuum condition imposed on the generators of Wp algebra.
Ambjørn, Jan, Watabiki, Y.
openaire +3 more sources
About the Dedekind psi function in Pauli graphs [PDF]
We study the commutation structure within the Pauli groups built on all decompositions of a given Hilbert space dimension $q$, containing a square, into its factors.
Planat, Michel R. P.
core +2 more sources

