Results 41 to 50 of about 5,103,286 (236)

Reanalyzing Head et al. (2015): investigating the robustness of widespread p-hacking [PDF]

open access: yesPeerJ, 2017
Head et al. (2015) provided a large collection of p-values that, from their perspective, indicates widespread statistical significance seeking (i.e., p-hacking). This paper inspects this result for robustness.
Chris H.J. Hartgerink
doaj   +2 more sources

Critique of p‐Values

open access: yesInternational Statistical Review, 2006
SummaryThis paper generalizes the notion of p‐value to obtain a system for assessing evidence in favor of an hypothesis. It is not quite a quantification in that evidence is a pair of numbers (the p‐value and the p‐value with null and alternative interchanged) with evidence for the alternative being claimed when the first number is small and the second
openaire   +2 more sources

Results of the Childhood Cancer and Leukaemia Group's United Kingdom Relapsed Wilms Tumour Trial

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The United Kingdom relapsed Wilms tumour (UKW‐R) trial aimed to improve the historically low survival rates after relapse of Wilms tumour (WT) through a prospective national risk‐stratified protocol. The trial also evaluated efficacy and toxicity of high‐dose melphalan.
Sucheta J. Vaidya   +10 more
wiley   +1 more source

The psychological reality of the learned “p < .05” boundary

open access: yesCognitive Research
The .05 boundary within Null Hypothesis Statistical Testing (NHST) “has made a lot of people very angry and been widely regarded as a bad move” (to quote Douglas Adams).
V. N. Vimal Rao   +2 more
doaj   +1 more source

Editorial: P-values, theory, replicability, and rigour

open access: yesDemographic Research, 2019
Background: In the light of the recent discussions about the statistical rigour of empirical research, including the interpretation and use of p-values and the importance of the theoretical underpinnings of population studies, the editorial board of ...
Jakub Bijak
doaj   +1 more source

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro   +10 more
wiley   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

pvclass: An R Package for p Values for Classification

open access: yesJournal of Statistical Software, 2017
Let (X, Y) be a random variable consisting of an observed feature vector X and an unobserved class label Y ∈ {1, 2, . . . , L} with unknown joint distribution.
Niki Zumbrunnen, Lutz Dümbgen
doaj   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

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