Results 111 to 120 of about 145,240 (241)
Pupil Plane Multiplexing for Vectorial Fourier Ptychography
This study proposes a cost‐effective, modality‐adaptive multichannel microscopy framework using pupil‐plane multiplexing. A custom pupil aperture at the Fourier plane encodes channel‐specific transfer functions with spectral or polarization filters, and model‐based reconstruction with channel‐dependent priors decodes them.
Hyesuk Chae +5 more
wiley +1 more source
Brownotate, a Comprehensive Solution to Generate Protein Sequence Databases for Any Species
ABSTRACT Proteomics is strengthening research in biology and the diversification of the model organisms studied is very promising for fully understanding the complexity of biological principles. However, the lack of protein sequence databases for many species is a major bottleneck.
Adrien Brown +4 more
wiley +1 more source
Outdoor Mosquito Control Using Odour-Baited Devices: Development and Evaluation of a Potential New Strategy to Complement Indoor Malaria Prevention Methods [PDF]
A considerable effort is currently underway to develop a malaria vaccine based on live Plasmodium falciparum sporozoites. The first requisite of a sporozoite vaccine is the guarantee of parasite arrest prior to the onset of the pathogenic blood stage ...
Kaindoa, Emmanuel W. +7 more
core
Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.
Intermittent preventive treatment in infants (IPTi) is an effective and safe malaria control strategy. However, it remains unclear what antimalarials should be used to replace sulfadoxine-pyrimethamine (SP) when and where SP is no longer an effective ...
Cairns, Matthew +5 more
core +1 more source
ABSTRACT Plant extracts are an important raw material for the development of new drugs. Rumex obtusifolius L., popularly known as ‘bitter dock’, has significant pharmacological properties. This study evaluated the in vitro antitrypanosomal activity of aqueous, hydroethanolic and ethanolic extracts from the leaf and roots of R. obtusifolius L.
Gabriela K. Borges +5 more
wiley +1 more source
Estudos "in vitro" dos níveis de resistência do Plasmodium falciparum a drogas, de 1983 a 1986
Foram realizados 171 testes de sensibilidade (microtécnica) com cepas de Plasmodium falciparum da Região Amazônica brasileira para cloroquina, mefloquina, amodiaquina e quinino.
M. A. V. Santos +3 more
doaj +1 more source
OBJECTIVES: To validate and quantify the impact of insecticide-treated bednets (ITN) on malaria morbidity and mortality in Cambodia. METHODS: A paired, cluster-randomized trial of ITN was conducted in Rattanakiri, North East Cambodia.
Alexander, N +8 more
core +1 more source
ABSTRACT Malaria in pregnancy poses significant risks to the mother, fetus, and neonate, necessitating effective treatment and prevention strategies. This study explored the application of an individualized (‘virtual twin’) physiologically‐based pharmacokinetic (PBPK) modeling approach to the antimalarial drug piperaquine in pregnant women.
Sonia Khier +3 more
wiley +1 more source
Inactivation of Plasmodium falciparum in whole blood by riboflavin plus irradiation.
BACKGROUND: Malaria parasites are frequently transmitted by unscreened blood transfusions in Africa. Pathogen reduction methods in whole blood would thus greatly improve blood safety.
Allain, Jean-Pierre +5 more
core +1 more source
AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li +5 more
wiley +1 more source

