Results 71 to 80 of about 66,832 (203)

Suboptimal Prophylaxis for P. falciparum [PDF]

open access: yesJournal of Travel Medicine, 1999
Van den Ende, J.   +2 more
openaire   +2 more sources

A multiplex assay to detect mosquito species, bloodmeal host source and Plasmodium in malaria vectors using Nanopore amplicon sequencing

open access: yesMedical and Veterinary Entomology, Volume 40, Issue 3, Page 465-477, September 2026.
Insectary‐reared mosquitoes were simultaneously assessed for species identification, bloodmeal source analysis and Plasmodium detection, using a single multiplexed sequencing run on the MinION sequencing platform. The method was applied to 150 insectary‐reared mosquitoes, representing nine species blood‐fed with five vertebrate hosts and 40 samples for
E. Abby Rogers   +5 more
wiley   +1 more source

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

open access: yesChemBioChem, Volume 27, Issue 15, 14 August 2026.
Organometallic derivatization of existing drugs is a common strategy to look for new drug candidates. This work describes the derivatization of the benzimidazole anthelmintic scaffold, from the synthesis of the organometallic derivatives to the evaluation of their biological properties. It highlights a broad range of antiparasitic activities and leaves
Corentin Ludwig   +14 more
wiley   +1 more source

Efek Pemberian ?-Mangostin dari Garcinia tetranda Pierre Terhadap Morfologi P.falciparum

open access: yesJournal of Tropical Pharmacy and Chemistry, 2011
Morphological changes assay to P. falciparum from the effects of α-mangostin from G. tetranda using TEM methods has been done. This test aims to determine the effect of mangostin on P.
Hadi Kuncoro
doaj   +1 more source

Actinomycin Derivatives: Structural Diversification and Biological Activities

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley   +1 more source

FREQUENCY OF VARIOUS HUMAN MALARIA INFECTIONS IN HOTTEST AREAS OF CENTRAL BALOCHISTAN,PAKISTAN: DUKI,HARNAI,AND SIBI

open access: yesPakistan Armed Forces Medical Journal, 2008
Objective: This study was designed to assess the frequency of malaria infection in human population Duki, Harnai and Sibi the hottest areas of centre Balochistan, Pakistan. Study Design: A descriptive study.
Mohammad Iqbal Yasinzai   +1 more
doaj   +2 more sources

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite   +10 more
wiley   +1 more source

Deconstruction of Aspartic Protease Inhibitors Enables Fragment‐Based Discovery of Plasmepsin V Inhibitors

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
A structure‐informed, fragment‐based approach was used to identify non‐peptidomimetic inhibitors of plasmepsin V. Pyrrolidine, piperidine, and piperazine containing fragments showed activity in a FRET assay. The optimization of the pyrrolidine scaffold resulted in N‐sulfonamide analogs with potency up to ~10 µM, establishing a promising scaffold for ...
Marija Skvorcova   +4 more
wiley   +1 more source

The power of many: when genetics met yeasts and high‐throughput

open access: yesBiological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Serum enzymes activities in Plasmodium falciparum infection in Southern Pakistan [PDF]

open access: yesArchives of Pharmacy Practice, 2011
Objective: Serum levels of lactate dehydrogenase (LDH),aspartate aminotranferase (AST), alanine aminotransferase(ALT), and alkaline phosphatase (ALP) were assessed todetermine the liver functions of patients infected withPlasmodium falciparum. The enzyme
Koay Yen Chin   +3 more
doaj  

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