Results 51 to 60 of about 24,188,006 (246)

A 5 year trend analysis of malaria prevalence with in the catchment areas of Felegehiwot referral Hospital, Bahir Dar city, northwest-Ethiopia: a retrospective study

BMC Research Notes, 2017
Background Malaria is one of the killer diseases in Ethiopia and it is still the first leading cause of death in health facilities. However, there is no information yet regarding the trends of malaria prevalence at health institution and particularly at ...
Mulat Yimer, Tadesse Hailu, Wondemagegn Mulu, Bayeh Abera, Workneh Ayalew   +4 more
doaj   +1 more source

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

American Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho, Hasrini Rini, Noy N. Kambuaya, Syawal Satria, Freis Candrawati, Putu A. I. Shanti, King Alexander, Benediktus Andries, Aisah R. Amelia, Anjana Rai, Kim A. Piera, Agatha M. Puspitasari, Ristya Amalia, Pak Prayoga, Leo Leonardo, Maulina Hafidzah, Theo Situmorang, Dewi S. Margayani, Desandra A. Rahmayenti, Pengxing Cao, Enny Kenangalem, Leily Trianty, Damian Oyong, Julie A. Simpson, Rintis Noviyanti, Pierre A. Buffet, Jeanne R. Poespoprodjo, Nicholas M. Anstey   +27 more
wiley   +1 more source

Probing the Clinical, Laboratory, and Sociodemographic Factors Associated with Malaria: A Case-Control Study

Journal of Pharmacy and Bioallied Sciences
Background: The National Malaria Elimination Program (NMEP) has helped reduce the mortality from malaria in India, and there are alarmingly high mortality rates from anemia in certain geographical regions.
Ritesh Upadhyay, Annasaheb J. Dhumale, Chanchlesh Dehariya, Renu Waghmare, Amit Rangari   +4 more
doaj   +1 more source

Alterations in cytokines and haematological parameters during the acute and convalescent phases of Plasmodium falciparum and Plasmodium vivax infections

Memorias do Instituto Oswaldo Cruz, 2014
Haematological and cytokine alterations in malaria are a broad and controversial subject in the literature. However, few studies have simultaneously evaluated various cytokines in a single patient group during the acute and convalescent phases of ...
Rodrigo Nunes Rodrigues-da-Silva, Josué da Costa Lima-Junior, Bruna de Paula Fonseca e Fonseca, Paulo Renato Zuquim Antas, Arlete Baldez, Fabio Luiz Storer, Fátima Santos, Dalma Maria Banic, Joseli de Oliveira-Ferreira   +8 more
doaj   +1 more source

Epidemiology of Plasmodium malariae and Plasmodium ovale spp. in Kinshasa Province, Democratic Republic of Congo

Nature Communications, 2023
Reports suggest non-falciparum species are an underappreciated cause of malaria in sub-Saharan Africa but their epidemiology is ill-defined, particularly in highly malaria-endemic regions.
Rachel Sendor, Kristin Banek, Melchior M. Kashamuka, Nono Mvuama, Joseph A. Bala, Marthe Nkalani, Georges Kihuma, Joseph Atibu, Kyaw L. Thwai, W. Matthew Svec, Varun Goel, Tommy Nseka, Jessica T. Lin, Jeffrey A. Bailey, Michael Emch, Margaret Carrel, Jonathan J. Juliano, Antoinette Tshefu, Jonathan B. Parr   +18 more
doaj   +1 more source

Glutaredoxine reduzieren schnell Glutathionhydroper‐ und Glutathionpolysulfide

Angewandte Chemie, EarlyView.
Glutaredoxine (Grx) reduzieren Glutathionpolysulfide (GSSnSG) schnell zu Glutathionhydroper/polysulfiden (GSSnH) oder GSSnH zu Wasserstoff(poly)sulfiden (H2Sn). Die Reduktion glutathionylierter Grx durch reduziertes Glutathion (GSH) liefert Glutathiondisulfid (GSSG).
Philipp Reinert, Seiryo Ogata, Laura Leiskau, Sernur Sena Yildiz, Takaaki Akaike, Uladzimir Barayeu, Marcel Deponte   +6 more
wiley   +1 more source

Invasion pathways and malaria severity in Kenyan Plasmodium falciparum clinical isolates. [PDF]

, 2007
The invasion of erythrocytes by Plasmodium falciparum occurs through multiple pathways that can be studied in vitro by examining the invasion of erythrocytes treated with enzymes such as neuraminidase, trypsin, and chymotrypsin.
Kai, Oscar, Conway, David J, Deans, Anne-Marie, Marsh, K, Conway, DJ, Conway, David J., Kai, O, Rowe, J. Alexandra, Rowe, J Alexandra; id_orcid, Marsh, Kevin, Deans, AM, Rowe, J Alexandra, Nery, S, Nery, Susana, Rowe, JA   +14 more
core   +1 more source

Glutaredoxins Rapidly Reduce Glutathione Hydroper‐ and Polysulfides

Angewandte Chemie International Edition, EarlyView.
Glutaredoxins (Grx) rapidly reduce glutathione polysulfides (GSSnSG) to glutathione hydroper/polysulfides (GSSnH) or GSSnH to hydrogen (poly)sulfides (H2Sn). Reduction of glutathionylated glutaredoxins by reduced glutathione (GSH) yields glutathione disulfide (GSSG).
Philipp Reinert, Seiryo Ogata, Laura Leiskau, Sernur Sena Yildiz, Takaaki Akaike, Uladzimir Barayeu, Marcel Deponte   +6 more
wiley   +1 more source

Trafficking of the exported P. falciparum chaperone PfHsp70x

Scientific Reports, 2016
AbstractPlasmodium falciparum extensively modifies its chosen host cell, the mature human erythrocyte. This remodelling is carried out by parasite-encoded proteins that are exported into the host cell. To gain access to the human red blood cell, these proteins must cross the parasitophorous vacuole, a membrane bound compartment surrounding the parasite
Rhiel, M, Bittl, V, Tribensky, A, Charnaud, SC, Strecker, M, Müller, S, Lanzer, M, Sanchez, C, Schaeffer-Reiss, C, Westermann, B, Crabb, BS, Gilson, PR, Külzer, S, Przyborski, JM   +13 more
openaire   +3 more sources

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source