Results 51 to 60 of about 145,240 (241)

Plasma concentration of parasite DNA as a measure of disease severity in falciparum malaria. [PDF]

, 2014
In malaria-endemic areas, Plasmodium falciparum parasitemia is common in apparently healthy children and severe malaria is commonly misdiagnosed in patients with incidental parasitemia.
Chhaganlal, Kajal D, Day, Nicholas PJ, Dondorp, Arjen M, Faiz, M Abul, Gesase, Samwel, Hendriksen, Ilse CE, Imwong, Mallika, Mishra, Saroj, Mohanty, Sanjib, Mtove, George, Seni, Amir, Veenemans, Jacobien, Verhoef, Hans, White, Nicholas J, Woodrow, Charles J   +14 more
core   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Epidemiology of Plasmodium malariae and Plasmodium ovale spp. in Kinshasa Province, Democratic Republic of Congo

Nature Communications, 2023
Reports suggest non-falciparum species are an underappreciated cause of malaria in sub-Saharan Africa but their epidemiology is ill-defined, particularly in highly malaria-endemic regions.
Rachel Sendor, Kristin Banek, Melchior M. Kashamuka, Nono Mvuama, Joseph A. Bala, Marthe Nkalani, Georges Kihuma, Joseph Atibu, Kyaw L. Thwai, W. Matthew Svec, Varun Goel, Tommy Nseka, Jessica T. Lin, Jeffrey A. Bailey, Michael Emch, Margaret Carrel, Jonathan J. Juliano, Antoinette Tshefu, Jonathan B. Parr   +18 more
doaj   +1 more source

Increased Plasmodium falciparum gametocyte production in mixed infections with P. malariae. [PDF]

, 2008
Plasmodium falciparum and P. malariae occur endemically in many parts of Africa. Observations from malariotherapy patients suggest that co-infection with P. malariae may increase P. falciparum gametocyte production. We determined P. falciparum gametocyte
Arens, Theo, Bousema, J Teun, Drakeley, Chris J, Gouagna, Louis C, Houben, Rein, Mens, Petra F, Omar, Sabah A, Sauerwein, Robert W, Schallig, Henk   +8 more
core   +1 more source

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

Clinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi, Mwila Mulubwa, Mmakwena M. Mmonwa, Mathew Njoroge, Liezl Krugmann, Kelly Chibale   +5 more
wiley   +1 more source

A 5 year trend analysis of malaria prevalence with in the catchment areas of Felegehiwot referral Hospital, Bahir Dar city, northwest-Ethiopia: a retrospective study

BMC Research Notes, 2017
Background Malaria is one of the killer diseases in Ethiopia and it is still the first leading cause of death in health facilities. However, there is no information yet regarding the trends of malaria prevalence at health institution and particularly at ...
Mulat Yimer, Tadesse Hailu, Wondemagegn Mulu, Bayeh Abera, Workneh Ayalew   +4 more
doaj   +1 more source

Plasmodium falciparum has rare correlation properties [PDF]

, 2012
A plot of the correlation function of a given DNA sequence has certain characteristic features common to almost all organisms. One common feature is that the correlation values at distances that are multiples of three is higher than correlation values at
Kushal Shah
core   +2 more sources

Trafficking of the exported P. falciparum chaperone PfHsp70x

Scientific Reports, 2016
AbstractPlasmodium falciparum extensively modifies its chosen host cell, the mature human erythrocyte. This remodelling is carried out by parasite-encoded proteins that are exported into the host cell. To gain access to the human red blood cell, these proteins must cross the parasitophorous vacuole, a membrane bound compartment surrounding the parasite
Rhiel, M, Bittl, V, Tribensky, A, Charnaud, SC, Strecker, M, Müller, S, Lanzer, M, Sanchez, C, Schaeffer-Reiss, C, Westermann, B, Crabb, BS, Gilson, PR, Külzer, S, Przyborski, JM   +13 more
openaire   +3 more sources

Quantitative electroencephalographic measures during postmalarial epileptogenesis

Epilepsia, EarlyView.
Abstract Objective Severe malaria with neurologic involvement contributes significantly to the global burden of acquired pediatric epilepsy. We studied quantitative electroencephalographic (EEG) measures in postmalarial epileptogenesis. Methods A total of 186 patients, aged 6 months to 11 years, with confirmed central nervous system malaria were ...
Rasesh B. Joshi, Suzanna Mwanza, Hitten P. Zaveri, Joseph Kasolo, Angela Masempela, Thelma Musakanya, Tina Mwale, Violet Nambeye, Rosemary Nyriongo, Ruth A. Tembo, Christopher Cortina, Bo Zhang, Gretchen L. Birbeck, Alexander Rotenberg, Archana A. Patel   +14 more
wiley   +1 more source

Alterations in cytokines and haematological parameters during the acute and convalescent phases of Plasmodium falciparum and Plasmodium vivax infections

Memorias do Instituto Oswaldo Cruz, 2014
Haematological and cytokine alterations in malaria are a broad and controversial subject in the literature. However, few studies have simultaneously evaluated various cytokines in a single patient group during the acute and convalescent phases of ...
Rodrigo Nunes Rodrigues-da-Silva, Josué da Costa Lima-Junior, Bruna de Paula Fonseca e Fonseca, Paulo Renato Zuquim Antas, Arlete Baldez, Fabio Luiz Storer, Fátima Santos, Dalma Maria Banic, Joseli de Oliveira-Ferreira   +8 more
doaj   +1 more source