Results 101 to 110 of about 23,411 (243)

Heterogeneity of virulence factors among Porphyromonas gingivalis clinical isolates from patients with chronic generalized periodontitis

Инфекция и иммунитет
The development of chronic generalized periodontitis occurs due to a combination of a several causes, among which the leading role is assigned to periodontal pathogens, which include P. gingivalis. Among P.
I. V. Koroleva, Ekaterina S. Mikhailova, K. A. Privalova, L. A. Ermolaeva, S. A. Tumanova, A. N. Suvorov   +5 more
doaj   +1 more source

Dysbiosis‐Mediated Inflammation: A Pathophysiological Link Between Rheumatoid Arthritis and Periodontitis

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To explore mechanistic links between rheumatoid arthritis (RA) and periodontitis (PD) through the lens of subgingival microbial dysbiosis–mediated inflammation. Methods Subgingival plaque from 100 volunteers with RA and PD (RAPD), 22 with RA (RAnoPD), 18 with PD (PDnoRA) and 19 healthy controls (noRAnoPD) was analysed using 16S‐amplicon ...
Isabel Lopez‐Oliva, Iain L. Chapple, Akshay Paropkari, Shweta Saraswat, Praveen Sharma, Stefan Serban, Paola de Pablo, Karim Raza, Andrew Filer, Thomas Dietrich, Melissa Grant, Purnima S. Kumar   +11 more
wiley   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Protective effects of a lactobacilli mixture against Alzheimer’s disease-like pathology triggered by Porphyromonas gingivalis

Scientific Reports
Porphyromonas gingivalis (P. gingivalis) is one of the pathogens involved in gingival inflammation, which may trigger neuroinflammatory diseases such as Alzheimer’s disease (AD).
Niloofar Kazemi, Mohammad Rabbani Khorasgani, Maryam Noorbakhshnia, Seyed Mohammad Razavi, Tahmineh Narimani, Narges Naghsh   +5 more
doaj   +1 more source

Associations Between Restoration Margins and Adjacent Periodontal Status—Longitudinal Results From SHIP‐TREND

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate the association between dental restorations and adjacent periodontal status over a 7‐year period, using data from a population‐based cohort study. Materials and Methods We used 7‐year follow‐up data on the restorative and periodontal statuses of 88,793 tooth surfaces from 2158 SHIP‐TREND (Study of Health in Pomerania ...
Patrick Nafz, Thomas Kocher, Christiane Pink, Sebastian‐Edgar Baumeister, Stefan Reckelkamm, Stefanie Samietz, Sonya Nafz, Henry Völzke, Philipp Kanzow, Birte Holtfreter   +9 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Harnessing Natural Quorum Sensing Inhibitors to Prevent Porphyromonas gingivalis-Induced Oral Squamous Cell Carcinoma: An Innovative Approach

Galician Medical Journal
The quest for effective cancer preventive strategies has led researchers to explore novel ways that go beyond conventional treatments. One such innovative method involves using natural quorum sensing inhibitory compounds to target Porphyromonas ...
Naji Naseef Pathoor, Pitchaipillai Sankar Ganesh   +1 more
doaj   +1 more source

Impact of Interdental Brushing on Pregnancy‐Associated Gingivitis: A Secondary Analysis of a Randomised Controlled Trial

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To assess whether daily use of calibrated interdental brushes can reduce gingival bleeding in pregnant women at high risk of preeclampsia. Materials and Methods In this multi‐centre randomised controlled trial, 323 nulliparous women at risk of preeclampsia and with an intact periodontium were enrolled at 12 weeks of gestation. Participants
Florence Carrouel, Aida Kanoute, Daouda Faye, Marta Mazur, Hervé Perrier, Flavia Vitiello, Roman Ardan, Céline Clément, Romain Lan, Denis Bourgeois   +9 more
wiley   +1 more source

Porphyromonas gingivalis hijacks mitophagy and lysosomal function to persist in endothelial cells

Frontiers in Cellular and Infection Microbiology
IntroductionThe direct infection of endothelial cells by Porphyromonas gingivalis (P. gingivalis), a keystone periodontal pathogen, has been implicated in the development of atherosclerosis.
Cheng Zheng, Jianmin Huang, Shengming Xu, Bin Lu, Hanxin Que, Tianhao Chen, Yubo Hou, Yubo Hou, Linlin He, Linlin He, Xia Fan, Fa-Ming Chen, Yi Wang, Yi Wang, Hui Deng, Hui Deng   +15 more
doaj   +1 more source

Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases

Journal of Gastroenterology and Hepatology, EarlyView.
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li, Jia Li, Robin P. F. Dullaart, Han Moshage   +3 more
wiley   +1 more source