Results 111 to 120 of about 52,654 (304)

Interaction between extracellular matrix molecules and microbial pathogens: evidence for the missing link in autoimmunity with rheumatoid arthritis as a disease model. [PDF]

, 2014
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation followed by tissue rebuilding or fibrosis. A failure by the body to regulate inflammation effectively is one of the hallmarks of RA.
Bella, Blombäck, Chang, De Almeida, De Rycke, Everse, Fan, Gregersen, Hynes, Ioan-Facsinay, Klareskog, Li, Mahdi, McInnes, Meyer, Mikuls, Mundlos, Panayi, Perry, Ruiz-Esquide, Scher, Scott, Sofat, Symmons, Van Beers, van der Woude, van Heemst, Vincent, Wegner, Wellcome Trust Case Control Consortium, Weyand, Williams   +31 more
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Impact of severe periodontitis and diabetes mellitus on recurrent cardiovascular outcomes

Journal of Periodontology, EarlyView.
Abstract Background This post hoc analysis of the Periodontitis and Coronary Heart Disease study (ClinicalTrials.gov Identifier: NCT01045070) aimed to determine the association between diabetes and recurrent cardiovascular events (CVEs) in patients with cardiovascular disease (CVD) and severe periodontitis.
Stefan Reichert, Axel Schlitt, Selina Rehm, Susanne Schulz   +3 more
wiley   +1 more source

Gingipain regulates isoform switches of PD-L1 in macrophages infected with Porphyromonas gingivalis

Scientific Reports
Periodontal pathogen Porphyromonas gingivalis (P. gingivalis) is believed to possess immune evasion capabilities, but it remains unclear whether this immune evasion is related to host gene alternative splicing (AS). In this study, RNA-sequencing revealed
Yilin Zheng, Ziyi Wang, Yao Weng, Heriati Sitosari, Yuhan He, Xiu Zhang, Noriko Shiotsu, Yoko Fukuhara, Mika Ikegame, Hirohiko Okamura   +9 more
doaj   +1 more source

Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling [PDF]

, 2017
The Gram-negative anaerobe Porphyromonas gingivalis is associated with chronic periodontitis. Clinical isolates of P. gingivalis strains with high dipeptidyl peptidase 4 (DPP4) expression also had a high capacity for biofilm formation and were more ...
Augustyns, Koen, De Meester, Ingrid, De Winter, Hans, Fülöp, Vilmos, Lambeir, Anne-Marie, Landuyt, Bart, Luyten, Walter, Rea, Dean, Schoofs, Liliane, Van Der Veken, Pieter, Van Elzen, Roos, Van Goethem, Sebastiaan   +11 more
core   +1 more source

Surveying immune and inflammatory alterations in periodontitis among individuals with Down syndrome: A preliminary cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro, João Victor Soares Rodrigues, Marta A. A. Nuernberg, Pedro Henrique Petrilli, Mabelle de Freitas Monteiro, Valdir Gouveia Garcia, Rafael Scaf de Molon, Renato Correa Viana Casarin   +7 more
wiley   +1 more source

Research progress on the potential mechanisms of Porphyromonas gingivalis in promoting Alzheimer’s disease [PDF]

口腔疾病防治
Alzheimer’s disease (AD), a common neurodegenerative disease, has been linked to periodontitis, especially Porphyromonas gingivalis (P. gingivalis) infection. This review summarizes the potential mechanisms and pathways through which P.
WANG Yujie, PENG Xian, LIAO Ga, ZHOU Xuedong
doaj   +1 more source

Oral Inflammation, Tooth Loss, Risk Factors, and Association with Progression of Alzheimer’s Disease [PDF]

, 2014
Periodontitis is a polymicrobial chronic inflammatory disease of tooth-supporting tissues with bacterial etiology affecting all age groups, becoming chronic in a subgroup of older individuals.
Crean, Stjohn, Harding, Alice, Kesavalu, Lakshmyya, Robinson, Sarita Jane, Simmons, Tal, Singhrao, Simarjit Kaur   +5 more
core   +1 more source

Predictability of a dental implant prognosis system: A retrospective study

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the predictability of the dental implant prognosis system proposed by Kwok et al. in 2023 by assessing implant survival rates across different initial prognosis categories over a 5‐year period. Methods Data were retrospectively collected from patients who received at least one dental implant from 2013 ...
Kristen Young, Michelle Tong, Yu‐Ting Yeh, Richard T. Kao, Guo‐Hao Lin   +4 more
wiley   +1 more source

Quorum sensing in Porphyromonas gingivalis and oral microbial interactions: a scoping review

Frontiers in Oral Health
ObjectivePorphyromonas gingivalis, a major periodontal pathogen, interacts with other oral microbes through quorum sensing, enhancing its growth and virulence, which contributes to periodontitis.
Zelda Ziyi Zhao, Wenwen Shan, Lifeng Guo, Chun Hung Chu, Jing Zhang, Jing Zhang   +5 more
doaj   +1 more source

KEMAMPUAN PORPHYROMONAS GINGIVALIS MEMPENGARUHI PERTUMBUHAN CANDIDA ALBICANS DALAM BERBAGAI PH SALIVA BUATAN [PDF]

, 2016
ABSTRAKNama : Vivi ZayantiProgram Studi : Kedokteran GigiJudul : Kemampuan Porphyromonas gingivalis MempengaruhiPertumbuhan Candida albicans dalam Berbagai pH Saliva BuatanKandidiasis rongga mulut dan periodontitis kronis termasuk penyakit infeksi rongga
Vivi Zayanti
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