Results 1 to 10 of about 25,979 (261)

Intracellular Porphyromonas gingivalis Promotes the Proliferation of Colorectal Cancer Cells via the MAPK/ERK Signaling Pathway

Frontiers in Cellular and Infection Microbiology, 2020
Porphyromonas gingivalis (P. gingivalis) is a keystone pathogen in periodontitis. However, several clinical studies have revealed an enrichment of P. gingivalis in the stool samples and colorectal mucosa of colorectal cancer patients.
Bin Cheng, Zhi Wang, Yiqun Jia
exaly   +3 more sources

Mechanisms of Porphyromonas gingivalis to translocate over the oral mucosa and other tissue barriers

Journal of Oral Microbiology, 2023
Introduction The oral pathogen Porphyromonas gingivalis is not only associated with periodontitis but also with systemic diseases elsewhere in the body. The mechanisms by which P.
Caroline A. de Jongh, Teun J. de Vries, Floris J. Bikker, Susan Gibbs, Bastiaan P. Krom   +4 more
doaj   +1 more source

Intraspecies Variability Affects Heterotypic Biofilms of Porphyromonas gingivalis and Prevotella intermedia: Evidences of Strain-Dependence Biofilm Modulation by Physical Contact and by Released Soluble Factors. [PDF]

PLoS ONE, 2015
It is well known that strain and virulence diversity exist within the population structure of Porphyromonas gingivalis. In the present study we investigate intra- and inter-species variability in biofilm formation of Porphyromonas gingivalis and partners
Graziela Murta Barbosa, Andrea Vieira Colombo, Paulo Henrique Rodrigues, Maria Regina Lorenzetti Simionato   +3 more
doaj   +1 more source

Role of nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 6 in activation of inflammation in human umbilical vein endothelial cells stimulated by Porphyromonas gingivalis-an in vitro study

Journal of Dental Sciences, 2023
Background/purpose: Porphyromonas gingivalis (P. gingivalis) could induce the activation of vascular endothelial cells and promote the formation of atherosclerosis.
Xinzhe Lou, Jianru Liu, Xiangying Ouyang, Wenyi Liu, Ying Xie, Jinsheng Zhong, Peiying Lv, Shengnan Zhang   +7 more
doaj   +1 more source

Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway

International Journal of Oral Science, 2023
Bacteremia induced by periodontal infection is an important factor for periodontitis to threaten general health. P. gingivalis DNA/virulence factors have been found in the brain tissues from patients with Alzheimer’s disease (AD). The blood-brain barrier
Shuang Lei, Jian Li, Jingjun Yu, Fulong Li, Yaping Pan, Xu Chen, Chunliang Ma, Weidong Zhao, Xiaolin Tang   +8 more
doaj   +1 more source

Clinical significance and prognostic value of Porphyromonas gingivalis infection in lung cancer

Translational Oncology, 2021
A variety of pathogenic microorganisms can promote the occurrence and development of malignant tumors by colonizing in the body. It has been shown that Porphyromonas gingivalis (P.
Yiwen Liu, Xiang Yuan, Kuisheng Chen, Fuyou Zhou, Haijun Yang, Hong Yang, Yijun Qi, Jinyu Kong, Wei Sun, Shegan Gao   +9 more
doaj   +1 more source

Phylogenomic analysis of the Porphyromonas gingivalis - Porphyromonas gulae duo: approaches to the origin of periodontitis

Frontiers in Microbiology, 2023
Porphyromonas gingivalis is an oral human pathogen associated with the onset and progression of periodontitis, a chronic immune-inflammatory disease characterized by the destruction of the teeth-supporting tissue. P.
Mauricio Morales-Olavarría, Josefa Nuñez-Belmar, Dámariz González, Emiliano Vicencio, Jaime Andres Rivas-Pardo, Jaime Andres Rivas-Pardo, Cristian Cortez, Juan P. Cárdenas, Juan P. Cárdenas   +8 more
doaj   +1 more source

The potency of Immunoglobulin Y anti Porphyromonas gingivalis to inhibit the adherence ability of Porphyromonas gingivalis on enterocytes

Dental Journal, 2020
Background: Pophyromonas gingivalis (P. gingivalis) bacteria are the main type of bacterium that cause chronic periodontitis. Immunoglobulin Y (IgY) is a type of immunoglobulin found in poultry, such as chickens and birds.
Nova Andriani Hepitaria, Indeswati Diyatri, Markus Budi Rahardjo, Rini Devijanti Ridwan   +3 more
doaj   +1 more source

Comparison of Porphyromonas gingivalis count and salivary immunoglobulin A against lipopolysaccharide of Porphyromonas gingivalis in periodontal health and disease

Dentistry and Medical Research, 2021
Background: Porphyromonas gingivalis (P. gingivalis) have been implicated to play a role in the pathogenesis of periodontal disease. Aim: The aim of this study was to compare P. gingivalis in subgingival plaque samples and salivary (immunoglobulin A [IgA]
Abhinav Subhashchandra Baheti, Pushpa S Pudakalkatti, Kishore G Bhat   +2 more
doaj   +1 more source

Roles of Oral Bacteria in Cardiovascular Diseases — From Molecular Mechanisms to Clinical Cases: Involvement of Porphyromonas gingivalis in the Development of Human Aortic Aneurysm

Journal of Pharmacological Sciences, 2010
Accumulating evidence suggests the involvement of Porphyromonas gingivalis (P. gingivalis), a periodontal pathogen, in cardiovascular diseases. Clinical specimens of aneurysmal tissue and dental plaque collected from patients infected with or without P ...
Koichiro Wada, Yoshinori Kamisaki
doaj   +1 more source