Results 21 to 30 of about 25,979 (261)

Porphyromonas gingivalis sphingolipids affect early responses of THP-1 macrophages to outer membrane vesicles

Infection and Immunity
Porphyromonas gingivalis is an oral bacterium commonly associated with periodontitis. P. gingivalis synthesizes sphingolipids (SLs), and recently, we reported that P.
Zavier G. Eure, Tamires Fernanda Vilas Boas Cordeiro, Alejandro Riveros Walker, Fernanda G. Rocha, Mary Ellen Davey, Frank C. Gibson   +5 more
doaj   +1 more source

Heme Competition Triggers an Increase in the Pathogenic Potential of Porphyromonas gingivalis in Porphyromonas gingivalis-Candida albicans Mixed Biofilm

Frontiers in Microbiology, 2020
As one of the main pathogens of periodontitis, Porphyromonas gingivalis often forms mixed biofilms with other bacteria or fungi under the gingiva, such as Candida albicans. Heme is an important iron source for P. gingivalis and C.
Yanyang Guo, Yu Wang, Yijin Wang, Yabing Jin, Chen Wang   +4 more
doaj   +1 more source

Development and evaluation of a saliva-based chair-side diagnostic for the detection of Porphyromonas gingivalis

Journal of Oral Microbiology, 2015
Porphyromonas gingivalis is a key pathogen in the polymicrobial biofilm that is associated with the oral disease chronic periodontitis. A number of studies have shown that in humans the level of P.
Neil M. O'Brien-Simpson, Kate Burgess, Gail C. Brammar, Ivan B. Darby, Eric C. Reynolds   +4 more
doaj   +1 more source

Inflammatory response of gut, spleen, and liver in mice induced by orally administered Porphyromonas gingivalis

Journal of Oral Microbiology, 2022
Background Periodontitis is a chronic multifactorial inflammatory disease. Porphyromonas gingivalis is a primary periopathogen in the initiation and development of periodontal disease. Evidence has shown that P.
Yingman Liu, Wenkai Huang, Ke Dai, Ni Liu, Jiaqi Wang, Xiaoying Lu, Jiaojiao Ma, Manman Zhang, Mengqi Xu, Xu Long, Jie Liu, Yurong Kou   +11 more
doaj   +1 more source

CXXC5 mitigates P. gingivalis-inhibited cementogenesis by influencing mitochondrial biogenesis. [PDF]

Cell Commun Signal, 2023
Abstract Background Cementoblasts are tooth-root surface-lining cells responsible for cementum formation (cementogenesis) and sensitive to Porphyromonas gingivalis stimulation. We have previously proved transcription factor CXXC-type zinc finger protein 5 (CXXC5) participates in cementogenesis.
Ma L, Wang H, Huang X, Huang H, Peng Y, Liu H, Wang X, Cao Z.   +7 more
europepmc   +4 more sources

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells

Mediators of Inflammation, 2018
It has been reported that periodontitis is associated with an increased risk of atherosclerosis. Accumulating evidence suggests that endothelial dysfunction is an early marker for atherosclerosis.
Masaaki Hirasawa, Tomoko Kurita-Ochiai
doaj   +1 more source

The efficacy of sarang semut extract (Myrmecodia pendens Merr & Perry) in inhibiting Porphyromonas gingivalis biofilm formation

Dental Journal, 2017
Background: Porphyromonas gingivalis (P. gingivalis) is a pathogenic bacteria present in the oral cavity involved in the pathogenesis of chronic periodontitis and biofilm.
Zulfan M. Alibasyah, Ambrosius Purba, Budi Setiabudiawan, Hendra Dian Adhita, Dikdik Kurnia, Mieke H. Satari   +5 more
doaj   +1 more source

Porphyromonas gingivalis Gingipain-Dependently Enhances IL-33 Production in Human Gingival Epithelial Cells. [PDF]

PLoS ONE, 2016
The cytokine IL-33 is constitutively expressed in epithelial cells and it augments Th2 cytokine-mediated inflammatory responses by regulating innate immune cells.
Hiroyuki Tada, Takashi Matsuyama, Takashi Nishioka, Makoto Hagiwara, Yusuke Kiyoura, Hidetoshi Shimauchi, Kenji Matsushita   +6 more
doaj   +1 more source

Host insulin resistance caused by Porphyromonas gingivalis-review of recent progresses

Frontiers in Cellular and Infection Microbiology, 2023
Porphyromonas gingivalis (P. gingivalis) is a Gram-negative oral anaerobic bacterium that plays a key role in the pathogenesis of periodontitis. P. gingivalis expresses a variety of virulence factors that disrupt innate and adaptive immunity, allowing P.
Shuxian Jia, Shuxian Jia, Xiaobing Li, Xiaobing Li, Qin Du   +4 more
doaj   +1 more source