Journal of Periodontology, EarlyView.Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis +15 more
wiley +1 more source
Development of an in vitro periodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules [PDF]
, 2014 Background: Inflammation within the oral cavity occurs due to dysregulation between microbial biofilms and the host response. Understanding how different oral hygiene products influence inflammatory properties is important for the development of new ...
AK Joe +44 more
core +1 more source
Journal of Periodontology, EarlyView.Abstract Background Evidence on the 16S metabarcoding of supragingival, subgingival, and salivary microbiomes in periodontal health remains limited. We aimed to analyze the diversity and potential of machine‐learning models of supragingival, subgingival, and salivary microbiomes in periodontal health. Methods A total of 848 samples (supragingival = 210;
Alba Regueira‐Iglesias +6 more
wiley +1 more source
Coinvasion of dentinal tubules by Porphyromonas gingivalis and Streptococcus gordonii depends upon binding specificity of streptococcal antigen I/II adhesin [PDF]
, 2000 Cell wall-anchored polypeptides of the antigen I/II family are produced by many species of oral streptococci. These proteins mediate adhesion of streptococci to salivary glycoproteins and to other oral microorganisms and promote binding of cells to ...
Jenkinson, Howard F. +3 more
core +2 more sources
Journal of Periodontology, EarlyView.Abstract Background This study investigated the association of inflammatory markers in saliva, plasma, and cerebrospinal fluid (CSF) with cognitive decline and periodontitis. Methods Patients with Alzheimer disease (AD, n = 52), mild cognitive impairment (MCI, n = 51), subjective cognitive decline (SCD, n = 51), and controls (n = 76) between 50 and 80 ...
Kåre Buhlin +5 more
wiley +1 more source
Investigating the biological properties of carbohydrate derived fulvic acid (CHD-FA) as a potential novel therapy for the management of oral biofilm infections. [PDF]
, 2013 Background: A number of oral diseases, including periodontitis, derive from microbial biofilms and are associated with increased antimicrobial resistance.
A Ahmad +34 more
core +2 more sources
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Journal of Periodontology, EarlyView.Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
Mitochondrial dysfunction promoted by Porphyromonas gingivalis lipopolysaccharide as a possible link between cardiovascular disease and periodontitis [PDF]
, 2011 Oxidative stress is one of the factors that could explain the pathophysiological mechanism of inflammatory conditions that occur in cardiovascular disease (CVD) and periodontitis.
Battino, Maurizio +5 more
core
Fungi at the scene of the crime: innocent bystanders or accomplices in oral infections? [PDF]
, 2018 Purpose of Review: Over the last decade, microbiome studies have enhanced our knowledge and understanding of the polymicrobial nature of oral infections.
Delaney, Christopher +6 more
core +2 more sources