Results 71 to 80 of about 24,766 (261)

Tolerance induced by Porphyromonas gingivalis may occur independently of TLR2 and TLR4. [PDF]

PLoS ONE, 2018
OBJECTIVE:Periodontitis is a microbe-induced chronic inflammatory disease. Previous exposure of the host to bacteria or their virulence factors leads to refractory responses to further stimuli, which is called tolerance.
Wei Lu, Jian-Yu Gu, Yao-Yao Zhang, Dan-Jun Gong, Yi-Ming Zhu, Ying Sun   +5 more
doaj   +1 more source

Does timing of systemic antibiotics influence periodontal treatment outcomes? A randomized clinical trial

Journal of Periodontology, EarlyView.
Abstract Background The aim of this study is to determine whether the timing of metronidazole (MTZ) and amoxicillin (AMX) administration, relative to scaling and root planing (SRP), influences the clinical and microbiological outcomes of periodontal treatment.
Daiane Fermiano, Eduardo de Souza Oliveira, Maria Josefa Mestnik, Luciene C. Figueiredo, Takahiko Shiba, Shunsuke Matsumura, Edson de Sousa, Helio Doyle, Rafael Oliveira Dias, Marcelo de Faveri, Magda Feres   +10 more
wiley   +1 more source

Electrolyzed saline as an alternative to chlorhexidine: Antimicrobial and biofilm volume outcomes in a 4‐day non‐brushing randomized controlled clinical trial

Journal of Periodontology, EarlyView.
Abstract Background The biofilm‐inhibitory effects of electrolyzed saline (EOS) vary widely due to differences in formulations and treatment methods. This study analyzed the impact of EOS on key oral microbial species and used serial 3D‐intraoral scans to evaluate its effects on de novo biofilm formation.
Katja Povšič, Haris Munjaković, Naiera Zayed, Wim Teughels, Katja Seme, Aleš Fidler, Rok Gašperšič   +6 more
wiley   +1 more source

Prevalence and local factors associated with radiographic bone loss in primary dentition: A retrospective study

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the radiographic bone level in primary molars in a Brazilian population, define the prevalence of bone loss, and identify the local factors associated with early bone alterations. Methods Radiographs of children who attended Piracicaba Dental School (Brazil) between 2014 and 2020 were evaluated.
Murilo C. Paraluppi, Camila S. Stolf, Bianca Mendes, Marcio Z. Casati, Karina G. Silvério, Enilson A. Sallum, Renato C. V. Casarin, Mabelle F. Monteiro   +7 more
wiley   +1 more source

Impact of severe periodontitis and diabetes mellitus on recurrent cardiovascular outcomes

Journal of Periodontology, EarlyView.
Abstract Background This post hoc analysis of the Periodontitis and Coronary Heart Disease study (ClinicalTrials.gov Identifier: NCT01045070) aimed to determine the association between diabetes and recurrent cardiovascular events (CVEs) in patients with cardiovascular disease (CVD) and severe periodontitis.
Stefan Reichert, Axel Schlitt, Selina Rehm, Susanne Schulz   +3 more
wiley   +1 more source

Porphyromonas gingivalis-derived outer membrane vesicles travel from oral to distant organs via blood circulation in a time-dependent manner

BMC Oral Health
Background Periodontitis is closely related to a variety of systemic diseases. Porphyromonas gingivalis (P. gingivalis) is one of the key pathogens of periodontitis. The influence of P.
Congcong Lv, Kaikai Shi, Zixin Guo, Pingchan Luo, Zhe Wu, Pei Yu   +5 more
doaj   +1 more source

Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors

iScience
Summary: Mechanisms by which Porphyromonas gingivalis (P. gingivalis) infection enhances oral tumor growth or resistance to cell death remain elusive. Here, we determined that P.
Megan Sheridan, Nityananda Chowdhury, Bridgette Wellslager, Natalia Oleinik, Mohamed Faisal Kassir, Han G. Lee, Mindy Engevik, Yuri Peterson, Subramanya Pandruvada, Zdzislaw M. Szulc, Özlem Yilmaz, Besim Ogretmen   +11 more
doaj   +1 more source

Surveying immune and inflammatory alterations in periodontitis among individuals with Down syndrome: A preliminary cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro, João Victor Soares Rodrigues, Marta A. A. Nuernberg, Pedro Henrique Petrilli, Mabelle de Freitas Monteiro, Valdir Gouveia Garcia, Rafael Scaf de Molon, Renato Correa Viana Casarin   +7 more
wiley   +1 more source

Porphyromonas gingivalis ATCC 33277 promotes intercellular adhesion molecule-1 expression in endothelial cells and monocyte-endothelial cell adhesion through macrophage migration inhibitory factor

BMC Microbiology, 2018
Background Porphyromonas gingivalis (P. gingivalis), one of the main pathogenic bacteria involved in periodontitis, induces the expression of intercellular adhesion molecule − 1 (ICAM-1) and monocyte-endothelial cell adhesion. This effect plays a pivotal
Wanyue Xu, Yaping Pan, Qiufang Xu, Yun Wu, Jiayu Pan, Jingya Hou, Li Lin, Xiaolin Tang, Chen Li, Jingbo Liu, Dongmei Zhang   +10 more
doaj   +1 more source

Predictability of a dental implant prognosis system: A retrospective study

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the predictability of the dental implant prognosis system proposed by Kwok et al. in 2023 by assessing implant survival rates across different initial prognosis categories over a 5‐year period. Methods Data were retrospectively collected from patients who received at least one dental implant from 2013 ...
Kristen Young, Michelle Tong, Yu‐Ting Yeh, Richard T. Kao, Guo‐Hao Lin   +4 more
wiley   +1 more source