Results 71 to 80 of about 20,775,577 (293)

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Anti-Porphyromonas gingivalis lipopolysaccharide antibody in rheumatoid arthritis patients with emphysema

Frontiers in Medicine
ObjectiveLung diseases that are chronic (emphysema [EMP], airway disease, interstitial lung disease) can complicate rheumatoid arthritis (RA) as extra-articular manifestations. Anti-Porphyromonas gingivalis (P. gingivalis) antibody (Ab) has been analyzed
Shomi Oka, Shomi Oka, Takashi Higuchi, Kota Shimada, Kota Shimada, Misuzu Fujimori, Atsushi Hashimoto, Atsushi Hashimoto, Akiko Komiya, Akiko Komiya, Koichiro Saisho, Koichiro Saisho, Norie Yoshikawa, Michita Suzuki, Toshihiro Matsui, Toshihiro Matsui, Naoshi Fukui, Naoshi Fukui, Kiyoshi Migita, Kiyoshi Migita, Kiyoshi Migita, Shigeto Tohma, Shigeto Tohma, Hiroshi Furukawa, Hiroshi Furukawa   +24 more
doaj   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Porphyromonas gingivalis traffics into endoplasmic reticulum-rich-autophagosomes for successful survival in human gingival epithelial cells

Virulence, 2018
Porphyromonas gingivalis, an opportunistic pathogen usurps gingival epithelial cells (GECs) as primary intracellular niche for its colonization in the oral mucosa.
Kyulim Lee, JoAnn S. Roberts, Chul Hee Choi, Kalina R. Atanasova, Özlem Yilmaz   +4 more
doaj   +1 more source

Effect of herbal mouthwash on periodontal parameters and P. gingivalis

Advances in Human Biology, 2017
Introduction: Inadequate control of dental plaque is one of the primary causative factors in the development of gingivitis and periodontal disease progression. Numerous agents have been available to reduce this plaque. Studies have shown the effects of chlorhexidine (CHX) and herbal mouthwash (HM) individually, but limited evidence has compared the ...
Sonam Mufti, Sarvagna Dadawala, Phoram Patel, Monali Shah, Deepak Dave   +4 more
openaire   +2 more sources

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Independent Prognostic Value of Natural Tooth Count Versus Posterior Teeth Occlusion in Resected Pancreatic Cancer

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose Prognostic significance of preoperative patient‐related factors, including oral health status, in pancreatic ductal adenocarcinoma (PDAC) remains unclear. We evaluated the association between preoperative factors—particularly oral health parameters—and long‐term survival after curative PDAC resection.
Kaoru Seo, Kenichiro Uemura, Kenjiro Okada, Hiromi Nishi, Tatsuaki Sumiyoshi, Ryuta Shintakuya, Yoshiaki Murakami, Hiroyuki Kawaguchi, Shinya Takahashi   +8 more
wiley   +1 more source

Peri‐implant disease pathogenesis animal models: Consensus report of Workgroup 1 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

Journal of Periodontology, EarlyView.
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis, Leonardo Mancini, Panos Afouxenides, Andrea Roccuzzo, IADR IRG Peri‐implantitis Best Evidence Consensus Working Group 1, Tara Aghaloo, Georgios Belibasakis, Nagihan Bostanci, Li Dehua, Nikolaos Donos, Alpdogan Kantarci, Alireza Moshaverinia, Flavia Pirih, Mia Rakic, Frank Schwarz, Sukirth Ganesan   +15 more
wiley   +1 more source

Prevalence and local factors associated with radiographic bone loss in primary dentition: A retrospective study

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the radiographic bone level in primary molars in a Brazilian population, define the prevalence of bone loss, and identify the local factors associated with early bone alterations. Methods Radiographs of children who attended Piracicaba Dental School (Brazil) between 2014 and 2020 were evaluated.
Murilo C. Paraluppi, Camila S. Stolf, Bianca Mendes, Marcio Z. Casati, Karina G. Silvério, Enilson A. Sallum, Renato C. V. Casarin, Mabelle F. Monteiro   +7 more
wiley   +1 more source

Predictability of a dental implant prognosis system: A retrospective study

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the predictability of the dental implant prognosis system proposed by Kwok et al. in 2023 by assessing implant survival rates across different initial prognosis categories over a 5‐year period. Methods Data were retrospectively collected from patients who received at least one dental implant from 2013 ...
Kristen Young, Michelle Tong, Yu‐Ting Yeh, Richard T. Kao, Guo‐Hao Lin   +4 more
wiley   +1 more source