Results 61 to 70 of about 24,000,753 (244)

Peri‐implant disease pathogenesis animal models: Consensus report of Workgroup 1 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

Journal of Periodontology, EarlyView.
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis, Leonardo Mancini, Panos Afouxenides, Andrea Roccuzzo, IADR IRG Peri‐implantitis Best Evidence Consensus Working Group 1, Tara Aghaloo, Georgios Belibasakis, Nagihan Bostanci, Li Dehua, Nikolaos Donos, Alpdogan Kantarci, Alireza Moshaverinia, Flavia Pirih, Mia Rakic, Frank Schwarz, Sukirth Ganesan   +15 more
wiley   +1 more source

Dasatinib and quercetin prevent alveolar bone loss in aged mice

Journal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli, Renata M. Moraes, Yuri C. Santos, Jaqueline L. Ribeiro, Maíra T. Garcia, Renata F. Prado, Florent Elefteriou, Ana Lia Anbinder   +7 more
wiley   +1 more source

Porphyromonas gingivalis traffics into endoplasmic reticulum-rich-autophagosomes for successful survival in human gingival epithelial cells

Virulence, 2018
Porphyromonas gingivalis, an opportunistic pathogen usurps gingival epithelial cells (GECs) as primary intracellular niche for its colonization in the oral mucosa.
Kyulim Lee, JoAnn S. Roberts, Chul Hee Choi, Kalina R. Atanasova, Özlem Yilmaz   +4 more
doaj   +1 more source

Quantification of Porphyromonas gingivalis by real time PCR : new primers targeting the rgpA and rgpB gene encoding RGP [PDF]

, 2003
P(論文)We designed new primers for the quantification of Porphyromonas gingivalis by real time PCR. The new primer set targeted the rgpA and rgpB genes that encode arginine specific cysteine proteinase (Arggingipain or Rgp), one of the putative pathogenic ...
KAMAGUCHI,Arihide/NAKAMURA,Reiko/OKAMOTO,Akimasa/WATANABE,Toshihiro/OHYAMA,Tohru/BABA,Hisae, 26499, 東日本学園大学歯学会   +2 more
core  

Zinc‐stabilized stannous fluoride modulates the periodontal microbiome, reducing Fusobacteria, key Gram‐negative species, and overall inflammation within an experimental gingivitis clinical trial

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the effects of a dentifrice containing stannous fluoride stabilized with zinc phosphate on subgingival microbiome composition and clinical inflammation during experimental gingivitis, compared with a sodium fluoride control. Methods This investigation was conducted as a secondary analysis of a randomized,
Kristopher A. Kerns, Allison A. Naumann, Lay Y. Soon, Erik L. Hendrickson, Abdelahhad Barbour, Dandan Chen, Harsh M. Trivedi, Michael Glogauer, Jeffrey S. McLean   +8 more
wiley   +1 more source

Porphyromonas gingivalis-derived outer membrane vesicles travel from oral to distant organs via blood circulation in a time-dependent manner

BMC Oral Health
Background Periodontitis is closely related to a variety of systemic diseases. Porphyromonas gingivalis (P. gingivalis) is one of the key pathogens of periodontitis. The influence of P.
Congcong Lv, Kaikai Shi, Zixin Guo, Pingchan Luo, Zhe Wu, Pei Yu   +5 more
doaj   +1 more source

Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors

iScience
Summary: Mechanisms by which Porphyromonas gingivalis (P. gingivalis) infection enhances oral tumor growth or resistance to cell death remain elusive. Here, we determined that P.
Megan Sheridan, Nityananda Chowdhury, Bridgette Wellslager, Natalia Oleinik, Mohamed Faisal Kassir, Han G. Lee, Mindy Engevik, Yuri Peterson, Subramanya Pandruvada, Zdzislaw M. Szulc, Özlem Yilmaz, Besim Ogretmen   +11 more
doaj   +1 more source

P. gingivalis Killing by Neutrophils

, 2013
Murine bone marrow-derived neutrophils isolated from wild-type and Cybb−/− animals were incubated with opsonized P. gingivalis (wild-type or Rbr− strain) at a ratio of 1:5 ratio in an aerobic or anaerobic atmosphere.
Maryta Sztukowska (19846), Yusuke Takahashi (19844), Jim Travis (19850), Hiromichi Yumoto (19845), Ky-Anh Nguyen (19852), L. Vincent Collins (19851), Malgorzata Kubica (19847), Frank C Gibson III (380330), Jan Potempa (19854), Caroline Attardo Genco (19853), Piotr Mydel (19843), Donald M Kurtz Jr. (380331)   +11 more
core   +1 more source

Periodontitis and gastric disorders: Systematic review and meta‐analysis of functional dyspepsia and Helicobacter pylori gastritis

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis has been associated with other systemic inflammatory diseases, such as cardiovascular disease, diabetes mellitus, and rheumatoid arthritis; through the translocation of oral bacteria and local inflammatory mediators systemically.
Hadeel Mohammed Abbood, Jasim Mohammed Abbood, Ekin Yay‐Kus, Iain L. C. Chapple   +3 more
wiley   +1 more source

Gingipain regulates isoform switches of PD-L1 in macrophages infected with Porphyromonas gingivalis

Scientific Reports
Periodontal pathogen Porphyromonas gingivalis (P. gingivalis) is believed to possess immune evasion capabilities, but it remains unclear whether this immune evasion is related to host gene alternative splicing (AS). In this study, RNA-sequencing revealed
Yilin Zheng, Ziyi Wang, Yao Weng, Heriati Sitosari, Yuhan He, Xiu Zhang, Noriko Shiotsu, Yoko Fukuhara, Mika Ikegame, Hirohiko Okamura   +9 more
doaj   +1 more source