Results 41 to 50 of about 20,775,577 (293)

Inflammatory response of gut, spleen, and liver in mice induced by orally administered Porphyromonas gingivalis

Journal of Oral Microbiology, 2022
Background Periodontitis is a chronic multifactorial inflammatory disease. Porphyromonas gingivalis is a primary periopathogen in the initiation and development of periodontal disease. Evidence has shown that P.
Yingman Liu, Wenkai Huang, Ke Dai, Ni Liu, Jiaqi Wang, Xiaoying Lu, Jiaojiao Ma, Manman Zhang, Mengqi Xu, Xu Long, Jie Liu, Yurong Kou   +11 more
doaj   +1 more source

Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'- phosphatase activities

Cellular Microbiology, 2009
Signal transduction following binding of lipopolysaccharide (LPS) to Toll‐like receptor 4 (TLR4) is an essential aspect of host innate immune responses to infection by Gram‐negative pathogens.
Stephen R. Coats, Jace W. Jones, C. Do, P. Braham, B. Bainbridge, T. T. To, David R. Goodlett, R. Ernst, R. Darveau   +8 more
semanticscholar   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

P. Gingivalils Induces Endothelial Dysfunction By mPTP Via Mitochondrial Fission

International Dental Journal
Aim or purpose: To explore the important role of Drp1-VDAC1-HK2 axis in regulating mitochondrial permeability transition pore (mPTP) opening in Porphyromonas gingivalis (P. gingivalis)-induced endothelial dysfunction.
Yi Wang, Shengming Xu, Hanxin Que
doaj   +1 more source

The efficacy of sarang semut extract (Myrmecodia pendens Merr & Perry) in inhibiting Porphyromonas gingivalis biofilm formation

Dental Journal, 2017
Background: Porphyromonas gingivalis (P. gingivalis) is a pathogenic bacteria present in the oral cavity involved in the pathogenesis of chronic periodontitis and biofilm.
Zulfan M. Alibasyah, Ambrosius Purba, Budi Setiabudiawan, Hendra Dian Adhita, Dikdik Kurnia, Mieke H. Satari   +5 more
doaj   +1 more source

A Blood‐Derived Double‐Network Hydrogel with Robust Wet Adhesion for Keratinized Mucosa Regeneration via Neutrophil Phenotype Reprogramming and Mechanophysical Niche Modulation

Advanced Science, EarlyView.
The iPRF‐MA/Alg‐NHS/Lut@EGCG (PGAE) double‐network hydrogel achieves durable wet adhesion in the oral environment. It simultaneously reprograms neutrophils from NETosis to phagocytosis for biofilm clearance, and activates the FAK‐RhoA‐YAP mechanotransduction pathway in gingival fibroblasts to drive extracellular matrix remodeling, thereby promoting ...
Sicong Ren, Xinting Yang, Jingxia Chen, Yihan Wang, Jian Feng, Jing Zhou, Jiaxin Luo, Jingjie Zhai, Quan Lin, Yanmin Zhou   +9 more
wiley   +1 more source

Tobacco Upregulates P. gingivalis Fimbrial Proteins Which Induce TLR2 Hyposensitivity

PLoS ONE, 2010
Background Tobacco smokers are more susceptible to periodontitis than non-smokers but exhibit reduced signs of clinical inflammation. The underlying mechanisms are unknown.
J. Bagaitkar, D. Demuth, C. Daep, D. Renaud, Deanne L. Pierce, D. Scott   +5 more
semanticscholar   +1 more source

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

Advanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou, Xiaolin Sun, Chengyu Liu, Yujia Shi, Meiqi Li, Meng Bo, Jingjie Zhai, Chunyan Li, Zhennan Wu, Xue Bai, Lin Wang   +10 more
wiley   +1 more source

Porphyromonas Gingivalis Survives In BMECs By Kgp Inhibiting Lysosomal Acidification

International Dental Journal
Aim or purpose: This study aimed to investigate Porphyromonas gingivalis (P. gingivalis) persistence in human brain microvascular endothelial cells (BMECs), its impact on cellular lysosomal acidification and regulatory mechanisms, given that brain ...
Angu Li, Xiaolin Tang
doaj   +1 more source

Host insulin resistance caused by Porphyromonas gingivalis-review of recent progresses

Frontiers in Cellular and Infection Microbiology, 2023
Porphyromonas gingivalis (P. gingivalis) is a Gram-negative oral anaerobic bacterium that plays a key role in the pathogenesis of periodontitis. P. gingivalis expresses a variety of virulence factors that disrupt innate and adaptive immunity, allowing P.
Shuxian Jia, Shuxian Jia, Xiaobing Li, Xiaobing Li, Qin Du   +4 more
doaj   +1 more source