Results 31 to 40 of about 24,000,753 (244)

Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells

Mediators of Inflammation, 2018
It has been reported that periodontitis is associated with an increased risk of atherosclerosis. Accumulating evidence suggests that endothelial dysfunction is an early marker for atherosclerosis.
Masaaki Hirasawa, Tomoko Kurita-Ochiai
doaj   +1 more source

The efficacy of sarang semut extract (Myrmecodia pendens Merr & Perry) in inhibiting Porphyromonas gingivalis biofilm formation

Dental Journal, 2017
Background: Porphyromonas gingivalis (P. gingivalis) is a pathogenic bacteria present in the oral cavity involved in the pathogenesis of chronic periodontitis and biofilm.
Zulfan M. Alibasyah, Ambrosius Purba, Budi Setiabudiawan, Hendra Dian Adhita, Dikdik Kurnia, Mieke H. Satari   +5 more
doaj   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

P. Gingivalils Induces Endothelial Dysfunction By mPTP Via Mitochondrial Fission

International Dental Journal
Aim or purpose: To explore the important role of Drp1-VDAC1-HK2 axis in regulating mitochondrial permeability transition pore (mPTP) opening in Porphyromonas gingivalis (P. gingivalis)-induced endothelial dysfunction.
Yi Wang, Shengming Xu, Hanxin Que
doaj   +1 more source

Representative enriched biological processes of U937 macrophage-like cells treated with the vehicle (Control-Vehicle), stimulated with the periodontopathogen P. gingivalis (P. gingivalis-Vehicle) and treated with the combination P. gingivalis-palmitate (P. gingivalis-Palmitate 0.3mM) for 24h.

, 2023
Representative enriched biological processes of U937 macrophage-like cells treated with the vehicle (Control-Vehicle), stimulated with the periodontopathogen P. gingivalis (P. gingivalis-Vehicle) and treated with the combination P.
Vanessa P. Houde (16469386), Fatiha Chandad (444729), Roberto D. Fanganiello (16469383), Joanna Mbuya Malaïka Mutombo (16469380), Xavier Minne (16469377)   +4 more
core   +1 more source

Protease‐Triggered Chromogenic Release From Peptide‐Modified Calcium Carbonate Microspheres Enables Colorimetric Detection of Porphyromonas gingivalis Activity

Advanced Science, EarlyView.
We report a chromogenic release‐based assay system with protease‐cleavage peptide‐modified calcium carbonate microspheres for colorimetric detection of Porphyromonas (P.) gingivalis activity. In response to Arg‐specific gingipain secreted by P. gingivalis, the supernatant becomes colored, enabling colorimetric analysis and providing the monitoring of ...
Yuki Hiruta, Zhicheng Jin, Mari Adachi, Lubna Amer, Natalia O. Tjokro, Diego F. Trujillo, Jan Potempa, Anthony J. O'Donoghue, Casey Chen, Jesse V. Jokerst   +9 more
wiley   +1 more source

Porphyromonas gingivalis outer membrane vesicles augments proliferation and metastasis of oral squamous cell carcinoma cells

BMC Oral Health
Background Porphyromonas gingivalis (P. gingivalis) is closely related to Oral squamous cell carcinoma (OSCC), and P. gingivalis outer membrane vesicles (OMVs) is the main pathogenic factor, which is associated with periodontitis, atherosclerosis and ...
Yanru Zeng, Yiyang Wang, Xiaona Shi, Yuanhao Zhao, Yue Tang, Shanshan Liu, Xiaofeng Zhu   +6 more
doaj   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

Porphyromonas Gingivalis Survives In BMECs By Kgp Inhibiting Lysosomal Acidification

International Dental Journal
Aim or purpose: This study aimed to investigate Porphyromonas gingivalis (P. gingivalis) persistence in human brain microvascular endothelial cells (BMECs), its impact on cellular lysosomal acidification and regulatory mechanisms, given that brain ...
Angu Li, Xiaolin Tang
doaj   +1 more source

Porphyromonas gingivalis Gingipain-Dependently Enhances IL-33 Production in Human Gingival Epithelial Cells. [PDF]

PLoS ONE, 2016
The cytokine IL-33 is constitutively expressed in epithelial cells and it augments Th2 cytokine-mediated inflammatory responses by regulating innate immune cells.
Hiroyuki Tada, Takashi Matsuyama, Takashi Nishioka, Makoto Hagiwara, Yusuke Kiyoura, Hidetoshi Shimauchi, Kenji Matsushita   +6 more
doaj   +1 more source