Results 31 to 40 of about 24,766 (261)

Assessment of antimicrobial efficacy of chitosan-based tetracycline gel on periodontal pathogens: An In vitro study

Journal of Pharmacy and Bioallied Sciences, 2023
Aim: The aim of the current research was to evaluate the antimicrobial effectiveness of chitosan-based tetracycline gel on periodontal pathogenic microorganisms.
Mohammad Jalaluddin, Avdhoot Kulkarni, Kavita Raj, Deesha Kumari, Konsam Bidya Devi, N S Vineeth   +5 more
doaj   +1 more source

In Vitro Immunomodulatory Effect of Linalool on P. gingivalis Infection

Global Journal of Medical Research, 2020
Introduction: Periodontitis is a multifactorial disease, characterized by an inflammatory response of the periodontal tissues to a dysbiotic biofilm in the subgingival surface. The presence of keystone pathogens, such as Porphyromonas gingivalis, is one of the main causes of dysbiosis, although the host response is preponderant ...
Santos R. P. B., Carvalho-Filho P. C., Sampaio G. P., Silva R. R., Falcão M. M. L., Pimentel A. C. M., Oliveira Y. A., Miranda P. M., Santos E. K. N., Meyer R., Xavier M. T., Trindade S. C.   +11 more
openaire   +2 more sources

Extracellular vesicles of P. gingivalis-infected macrophages induce lung injury

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2021
Periodontal diseases are common inflammatory diseases that are induced by infection with periodontal bacteria such as Porphyromonas gingivalis (Pg). The association between periodontal diseases and many types of systemic diseases has been demonstrated; the term "periodontal medicine" is used to describe how periodontal infection/inflammation may impact
Kayo Yoshida, Kaya Yoshida, Natsumi Fujiwara, Mariko Seyama, Kisho Ono, Hotaka Kawai, Jiajie Guo, Ziyi Wang, Yao Weng, Yaqiong Yu, Yoko Uchida-Fukuhara, Mika Ikegame, Akira Sasaki, Hitoshi Nagatsuka, Hiroshi Kamioka, Hirohiko Okamura, Kazumi Ozaki   +16 more
openaire   +2 more sources

Inflammatory response of gut, spleen, and liver in mice induced by orally administered Porphyromonas gingivalis

Journal of Oral Microbiology, 2022
Background Periodontitis is a chronic multifactorial inflammatory disease. Porphyromonas gingivalis is a primary periopathogen in the initiation and development of periodontal disease. Evidence has shown that P.
Yingman Liu, Wenkai Huang, Ke Dai, Ni Liu, Jiaqi Wang, Xiaoying Lu, Jiaojiao Ma, Manman Zhang, Mengqi Xu, Xu Long, Jie Liu, Yurong Kou   +11 more
doaj   +1 more source

The efficacy of sarang semut extract (Myrmecodia pendens Merr & Perry) in inhibiting Porphyromonas gingivalis biofilm formation

Dental Journal, 2017
Background: Porphyromonas gingivalis (P. gingivalis) is a pathogenic bacteria present in the oral cavity involved in the pathogenesis of chronic periodontitis and biofilm.
Zulfan M. Alibasyah, Ambrosius Purba, Budi Setiabudiawan, Hendra Dian Adhita, Dikdik Kurnia, Mieke H. Satari   +5 more
doaj   +1 more source

P. Gingivalils Induces Endothelial Dysfunction By mPTP Via Mitochondrial Fission

International Dental Journal
Aim or purpose: To explore the important role of Drp1-VDAC1-HK2 axis in regulating mitochondrial permeability transition pore (mPTP) opening in Porphyromonas gingivalis (P. gingivalis)-induced endothelial dysfunction.
Yi Wang, Shengming Xu, Hanxin Que
doaj   +1 more source

Lipopolysaccharide Preparation Derived From Porphyromonas gingivalis Induces a Weaker Immuno-Inflammatory Response in BV-2 Microglial Cells Than Escherichia coli by Differentially Activating TLR2/4-Mediated NF-κB/STAT3 Signaling Pathways

Frontiers in Cellular and Infection Microbiology, 2021
Alzheimer’s disease (AD) is a degenerative disease of the central nervous system with unclear etiology and pathogenesis. In recent years, as the infectious theory and endotoxin hypothesis of AD has gained substantial attention, several studies have ...
Che Qiu, Che Qiu, Zhen Yuan, Zhiyan He, Zhiyan He, Huiwen Chen, Huiwen Chen, Yue Liao, Yue Liao, Shiliang Li, Wei Zhou, Wei Zhou, Zhongchen Song, Zhongchen Song   +13 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Porphyromonas Gingivalis Survives In BMECs By Kgp Inhibiting Lysosomal Acidification

International Dental Journal
Aim or purpose: This study aimed to investigate Porphyromonas gingivalis (P. gingivalis) persistence in human brain microvascular endothelial cells (BMECs), its impact on cellular lysosomal acidification and regulatory mechanisms, given that brain ...
Angu Li, Xiaolin Tang
doaj   +1 more source

Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells

Mediators of Inflammation, 2018
It has been reported that periodontitis is associated with an increased risk of atherosclerosis. Accumulating evidence suggests that endothelial dysfunction is an early marker for atherosclerosis.
Masaaki Hirasawa, Tomoko Kurita-Ochiai
doaj   +1 more source