Results 31 to 40 of about 52,654 (304)

Development and evaluation of a saliva-based chair-side diagnostic for the detection of Porphyromonas gingivalis

Journal of Oral Microbiology, 2015
Porphyromonas gingivalis is a key pathogen in the polymicrobial biofilm that is associated with the oral disease chronic periodontitis. A number of studies have shown that in humans the level of P.
Neil M. O'Brien-Simpson, Kate Burgess, Gail C. Brammar, Ivan B. Darby, Eric C. Reynolds   +4 more
doaj   +1 more source

Lipopolysaccharide Preparation Derived From Porphyromonas gingivalis Induces a Weaker Immuno-Inflammatory Response in BV-2 Microglial Cells Than Escherichia coli by Differentially Activating TLR2/4-Mediated NF-κB/STAT3 Signaling Pathways

Frontiers in Cellular and Infection Microbiology, 2021
Alzheimer’s disease (AD) is a degenerative disease of the central nervous system with unclear etiology and pathogenesis. In recent years, as the infectious theory and endotoxin hypothesis of AD has gained substantial attention, several studies have ...
Che Qiu, Che Qiu, Zhen Yuan, Zhiyan He, Zhiyan He, Huiwen Chen, Huiwen Chen, Yue Liao, Yue Liao, Shiliang Li, Wei Zhou, Wei Zhou, Zhongchen Song, Zhongchen Song   +13 more
doaj   +1 more source

Dysbiosis by neutralizing commensal mediated inhibition of pathobionts [PDF]

, 2016
Dysbiosis in the periodontal microbiota is associated with the development of periodontal diseases. Little is known about the initiation of dysbiosis.
Bernaerts, Kristel, Boon, Nico, Hernandez Sanabria, Emma, Herrero, Esteban Rodriguez, Quirynen, Marc, Slomka, Vera, Teughels, Wim   +6 more
core   +3 more sources

LPS from P. gingivalis Negatively Alters Gingival Cell Mitochondrial Bioenergetics [PDF]

International Journal of Dentistry, 2017
Objective. Oral inflammatory pathologies are linked to increased oxidative stress, thereby partly explaining their relevance in the etiology of systemic disorders. The purpose of this work was to determine the degree to which LPS from Porphyromonas gingivalis, the primary pathogen related to oral inflammation, altered gingival mitochondrial function ...
Kiran Napa, Andrea C. Baeder, Jeffrey E. Witt, Sarah T. Rayburn, Madison G. Miller, Blake W. Dallon, Jonathan L. Gibbs, Shalene H. Wilcox, Duane R. Winden, Jared H. Smith, Paul R. Reynolds, Benjamin T. Bikman   +11 more
openaire   +3 more sources

Polymicrobial oral biofilm models: simplifying the complex [PDF]

, 2019
Over the past century, numerous studies have used oral biofilm models to investigate growth kinetics, biofilm formation, structure and composition, antimicrobial susceptibility and host–pathogen interactions.
Appelbaum, Black, Bradshaw, Bryn Short, Ceri, Christopher Delaney, Darveau, Fitzgerald, Gibbons, Gordon Ramage, Hamilton, Jason L. Brown, John Butcher, Lie, Loesche, Loesche, Marcello Riggio, Mark C. Butcher, Marsh, Marsh, McKee, Miller, Orstavik, Pratten, Russell, Shauna Culshaw, Sudo, Sudo, Tracy Young, William Johnston   +29 more
core   +3 more sources

Porphyromonas gingivalis Gingipain-Dependently Enhances IL-33 Production in Human Gingival Epithelial Cells. [PDF]

PLoS ONE, 2016
The cytokine IL-33 is constitutively expressed in epithelial cells and it augments Th2 cytokine-mediated inflammatory responses by regulating innate immune cells.
Hiroyuki Tada, Takashi Matsuyama, Takashi Nishioka, Makoto Hagiwara, Yusuke Kiyoura, Hidetoshi Shimauchi, Kenji Matsushita   +6 more
doaj   +1 more source

Association between anti-Porphyromonas gingivalis or anti-α-enolase antibody and severity of periodontitis or rheumatoid arthritis (RA) disease activity in RA [PDF]

, 2015
BACKGROUND: Periodontitis (PD) has been reported to be associated with rheumatoid arthritis (RA). Porphyromonas gingivalis (P. gingivalis) is a gram-negative anaerobic bacterium that is recognized as one of the major pathogenic organisms in PD and is the
Eun Bong Lee, Eun Young Lee, In Ah Choi, Jin-Hee Kim, Joo Youn Lee, Kyoung-Hwa Kim, Yeong Wook Song, Yong-Moo Lee   +7 more
core   +1 more source

Optimization of quantitative polymerase chain reactions for detection and quantification of eight periodontal bacterial pathogens [PDF]

, 2012
BACKGROUND: The aim of this study was to optimize quantitative (real-time) polymerase chain reaction (qPCR) assays for 8 major periodontal pathogens, i.e.
Cosyn, Jan, De Bruyn, Hugo, Decat, Ellen, Deschaght, Pieter, Miremadi, Seyed Reza, Saerens, Bart, Van Mechelen, Els, Vaneechoutte, Mario, Vermeulen, Stefan   +8 more
core   +1 more source

Platelet aggregation promoted by biofilms of oral bacteria and the effect of mouth rinses in vitro

Journal of Infection in Developing Countries, 2016
Introduction: The purpose of this study was to observe platelet aggregation promoted by biofilms of Streptococcus sanguinis and Porphyromonas gingivalis and to evaluate the effect of two different mouth rinses on this process.
Yan Tu, Yadong Chen, Chongyang Zheng, Hui Chen   +3 more
doaj   +1 more source

Heme Competition Triggers an Increase in the Pathogenic Potential of Porphyromonas gingivalis in Porphyromonas gingivalis-Candida albicans Mixed Biofilm

Frontiers in Microbiology, 2020
As one of the main pathogens of periodontitis, Porphyromonas gingivalis often forms mixed biofilms with other bacteria or fungi under the gingiva, such as Candida albicans. Heme is an important iron source for P. gingivalis and C.
Yanyang Guo, Yu Wang, Yijin Wang, Yabing Jin, Chen Wang   +4 more
doaj   +1 more source