Results 31 to 40 of about 20,775,577 (293)

Development and evaluation of a saliva-based chair-side diagnostic for the detection of Porphyromonas gingivalis

Journal of Oral Microbiology, 2015
Porphyromonas gingivalis is a key pathogen in the polymicrobial biofilm that is associated with the oral disease chronic periodontitis. A number of studies have shown that in humans the level of P.
Neil M. O'Brien-Simpson, Kate Burgess, Gail C. Brammar, Ivan B. Darby, Eric C. Reynolds   +4 more
doaj   +1 more source

Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase

International Journal of Oral Science, 2021
Ulcerative Colitis (UC) has been reported to be related to Porphyromonas gingivalis (P. gingivalis). Porphyromonas gingivalis peptidylarginine deiminase (PPAD), a virulence factor released by P. gingivalis, is known to induce inflammatory responses.
Xida Zhao, Jingbo Liu, Chong Zhang, Ning Yu, Ze Lu, Shuwei Zhang, Yuchao Li, Qian Li, Junchao Liu, Dongjuan Liu, Yaping Pan   +10 more
doaj   +1 more source

Assessment of antimicrobial efficacy of chitosan-based tetracycline gel on periodontal pathogens: An In vitro study

Journal of Pharmacy and Bioallied Sciences, 2023
Aim: The aim of the current research was to evaluate the antimicrobial effectiveness of chitosan-based tetracycline gel on periodontal pathogenic microorganisms.
Mohammad Jalaluddin, Avdhoot Kulkarni, Kavita Raj, Deesha Kumari, Konsam Bidya Devi, N S Vineeth   +5 more
doaj   +1 more source

P. gingivalis-Nucleoside-diphosphate-kinase Inhibits ATP-Induced Reactive-Oxygen-Species via P2X7 Receptor/NADPH-Oxidase Signaling and Contributes to Persistence

Cellular Microbiology, 2013
Ligation of P2X7 receptors with a ‘danger signal’, extracellular ATP (eATP), has recently been shown to result in production of intracellular reactive‐oxygen‐species (ROS) in macrophages.
Chul Hee Choi, R. Spooner, Jefferson DeGuzman, Theofilos Koutouzis, David M. Ojcius, Ö. Yilmaz   +5 more
semanticscholar   +1 more source

Platelet aggregation promoted by biofilms of oral bacteria and the effect of mouth rinses in vitro

Journal of Infection in Developing Countries, 2016
Introduction: The purpose of this study was to observe platelet aggregation promoted by biofilms of Streptococcus sanguinis and Porphyromonas gingivalis and to evaluate the effect of two different mouth rinses on this process.
Yan Tu, Yadong Chen, Chongyang Zheng, Hui Chen   +3 more
doaj   +1 more source

Heme Competition Triggers an Increase in the Pathogenic Potential of Porphyromonas gingivalis in Porphyromonas gingivalis-Candida albicans Mixed Biofilm

Frontiers in Microbiology, 2020
As one of the main pathogens of periodontitis, Porphyromonas gingivalis often forms mixed biofilms with other bacteria or fungi under the gingiva, such as Candida albicans. Heme is an important iron source for P. gingivalis and C.
Yanyang Guo, Yu Wang, Yijin Wang, Yabing Jin, Chen Wang   +4 more
doaj   +1 more source

Lipopolysaccharide Preparation Derived From Porphyromonas gingivalis Induces a Weaker Immuno-Inflammatory Response in BV-2 Microglial Cells Than Escherichia coli by Differentially Activating TLR2/4-Mediated NF-κB/STAT3 Signaling Pathways

Frontiers in Cellular and Infection Microbiology, 2021
Alzheimer’s disease (AD) is a degenerative disease of the central nervous system with unclear etiology and pathogenesis. In recent years, as the infectious theory and endotoxin hypothesis of AD has gained substantial attention, several studies have ...
Che Qiu, Che Qiu, Zhen Yuan, Zhiyan He, Zhiyan He, Huiwen Chen, Huiwen Chen, Yue Liao, Yue Liao, Shiliang Li, Wei Zhou, Wei Zhou, Zhongchen Song, Zhongchen Song   +13 more
doaj   +1 more source

P. gingivalis promotes Th17 inducing pathways in chronic periodontitis

Journal of Autoimmunity, 2012
In periodontitis, a common chronic inflammatory condition, gram negative-rich bacterial biofilms trigger, in susceptible individuals, perpetuating inflammation that results in extensive tissue damage of tooth supporting structures.
N. Moutsopoulos, Heather M. Kling, N. Angelov, W. Jin, R. Palmer, S. Nares, M. Osorio, S. Wahl   +7 more
semanticscholar   +1 more source

Determination of the Genome Sequence of Porphyromonas gingivalis Strain ATCC 33277 and Genomic Comparison with Strain W83 Revealed Extensive Genome Rearrangements in P. gingivalis

DNA Research, 2008
The gram-negative anaerobic bacterium Porphyromonas gingivalis is a major causative agent of chronic periodontitis. Porphyromonas gingivalis strains have been classified into virulent and less-virulent strains by mouse subcutaneous soft tissue abscess ...
M. Naito, H. Hirakawa, A. Yamashita, N. Ohara, M. Shoji, H. Yukitake, K. Nakayama, Hidehiro Toh, F. Yoshimura, S. Kuhara, M. Hattori, Tetsuya Hayashi, K. Nakayama   +12 more
semanticscholar   +1 more source

Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells

Mediators of Inflammation, 2018
It has been reported that periodontitis is associated with an increased risk of atherosclerosis. Accumulating evidence suggests that endothelial dysfunction is an early marker for atherosclerosis.
Masaaki Hirasawa, Tomoko Kurita-Ochiai
doaj   +1 more source