A study of the invasion and the cellular response of an in vitro 3D oral mucosal model by Porphyromonas gingivalis [PDF]
, 2012 Periodontitis is a leading cause of tooth loss worldwide. The Gram-negative anaerobe, Porphyromonas gingivalis, has been implicated in the initiation and cyclical progression of this inflammatory disease, which may be associated with its ability to ...
Pinnock, Abigail
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Interactions of porphyromonas gingivalis with bone marrow cells: implications on mediators of bone resorption [PDF]
, 2012 PhDPeriodontitis is a multi-factorial disease characterised by the loss of connective tissue and underlying alveolar bone leading to the loss of teeth. Porphyromonas gingivalis (P.
Reddi, Durga
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Magnesium Enhances Immune Clearance of P. gingivalis in Macrophages by Suppressing MCU-Mediated Mitochondrial Calcium Overload. [PDF]
Cell ProlifMagnesium restores macrophage clearance of P. gingivalis by inhibiting MCU‐mediated calcium overload. P. gingivalis is mainly phagocytosed by macrophages but escapes intracellular clearance via MCU‐mediated mitochondrial and cytosolic Ca2+ overload in periodontitis. The persistent P.
Deng DK +11 more
europepmc +2 more sources
Transcriptional Profiling of Bone Marrow Stromal Cells in Response to Porphyromonas gingivalis Secreted Products [PDF]
, 2012 Periodontitis is an infectious inflammatory disease that destroys the tooth-supporting (periodontal) tissues. Porphyromonas gingivalis is an oral pathogen highly implicated in the pathogenesis of this disease.
Reddi, D +9 more
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Interleukin-1[Alpha] production in periodontal disease: the interaction of bacteria and gene polymorphisms. [PDF]
, 2007 PhDThere is good evidence that interleukin-I alpha (IL-Ia) plays a key role in both the host response to bacteria and the tissue destruction associated with periodontal disease.
Bostanci, Nagihan
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TLR2 activation by Porphyromonas gingivalis requires both PPAD activity and fimbriae [PDF]
, 2022 Porphyromonas gingivalis, a keystone oral pathogen implicated in development and progression of periodontitis, may also contribute to the pathogenicity of diseases such as arthritis, atherosclerosis, and Alzheimer's. P. gingivalis is a master manipulator
Grabiec, Aleksander +10 more
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Journal of Pharmacological Sciences, 2010 Accumulating evidence suggests the involvement of Porphyromonas gingivalis (P. gingivalis), a periodontal pathogen, in cardiovascular diseases. Clinical specimens of aneurysmal tissue and dental plaque collected from patients infected with or without P ...
Koichiro Wada, Yoshinori Kamisaki
doaj +1 more source
HETEROGENEITY OF PORPHYROMONAS GINGIVALIS STRAINS ON FIMBRILLIN GENE LOCUS BY RESTRICTION FRAGMENT LENGTH POLYMORPHISM ANALYSIS [PDF]
, 1993 The adherence of Porphyromonas gingivalis (P. gingivalis) to the periodontal tissue may be an initial step in the pathogenesis of periodontal disease, and fimbriae is believed to play an important role in such processes. However, the heterogeneity of the
Yi, Jie ZHANG
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Platelet aggregation promoted by biofilms of oral bacteria and the effect of mouth rinses in vitro
Journal of Infection in Developing Countries, 2016 Introduction: The purpose of this study was to observe platelet aggregation promoted by biofilms of Streptococcus sanguinis and Porphyromonas gingivalis and to evaluate the effect of two different mouth rinses on this process.
Yan Tu +3 more
doaj +1 more source
Antimicrobial and anti-inflammatory activity of Cystatin C on human gingival fibroblast incubated with Porphyromonas gingivalis [PDF]
PeerJ, 2022 Background Periodontal disease is considered one of the most prevalent chronic infectious diseases, often leading to the disruption of tooth-supporting tissues, including alveolar bone, causing tooth mobility and loss.
Blanca Esther Blancas-Luciano +7 more
doaj +2 more sources