Results 11 to 20 of about 24,766 (261)

CXXC5 mitigates P. gingivalis-inhibited cementogenesis by influencing mitochondrial biogenesis. [PDF]

open access: yesCell Commun Signal, 2023
Abstract Background Cementoblasts are tooth-root surface-lining cells responsible for cementum formation (cementogenesis) and sensitive to Porphyromonas gingivalis stimulation. We have previously proved transcription factor CXXC-type zinc finger protein 5 (CXXC5) participates in cementogenesis.
Ma L   +7 more
europepmc   +4 more sources

Intracellular Porphyromonas gingivalis Promotes the Proliferation of Colorectal Cancer Cells via the MAPK/ERK Signaling Pathway

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Porphyromonas gingivalis (P. gingivalis) is a keystone pathogen in periodontitis. However, several clinical studies have revealed an enrichment of P. gingivalis in the stool samples and colorectal mucosa of colorectal cancer patients.
Wenxin Mu, Yiqun Jia, Zhi Wang
exaly   +3 more sources

Multi-omics insights reveal the remodeling of gut mycobiome with P. gingivalis. [PDF]

open access: yesFront Cell Infect Microbiol, 2022
As a keystone periodontal pathogen, Porphyromonas gingivalis (P. gingivalis) was suggested to be involved in the progression of systemic diseases by altering the intestinal microecology. However, studies concerning gut microbiome have focused entirely on the bacterial component, while the fungal community (gut mycobiome) has been overlooked.
Chen S, Niu C, Lv W.
europepmc   +4 more sources

Curry Leaf Triggers Cell Death of P. gingivalis with Membrane Blebbing. [PDF]

open access: yesPathogens, 2021
Periodontal disease has become a serious public health problem, as indicated by accumulating evidence that periodontal disease is not only a major cause of tooth loss but is also associated with various systemic diseases. The present study assessed the anti-bacterial activities of three herbal products (curry leaf, clove, and cinnamon) against ...
Nakao R   +3 more
europepmc   +5 more sources

Heme Competition Triggers an Increase in the Pathogenic Potential of Porphyromonas gingivalis in Porphyromonas gingivalis-Candida albicans Mixed Biofilm

open access: yesFrontiers in Microbiology, 2020
As one of the main pathogens of periodontitis, Porphyromonas gingivalis often forms mixed biofilms with other bacteria or fungi under the gingiva, such as Candida albicans. Heme is an important iron source for P. gingivalis and C.
Yabing Jin, Chen Wang
exaly   +3 more sources

Mechanisms of Porphyromonas gingivalis to translocate over the oral mucosa and other tissue barriers

open access: yesJournal of Oral Microbiology, 2023
Introduction The oral pathogen Porphyromonas gingivalis is not only associated with periodontitis but also with systemic diseases elsewhere in the body. The mechanisms by which P.
Caroline A. de Jongh   +4 more
doaj   +1 more source

Intraspecies Variability Affects Heterotypic Biofilms of Porphyromonas gingivalis and Prevotella intermedia: Evidences of Strain-Dependence Biofilm Modulation by Physical Contact and by Released Soluble Factors. [PDF]

open access: yesPLoS ONE, 2015
It is well known that strain and virulence diversity exist within the population structure of Porphyromonas gingivalis. In the present study we investigate intra- and inter-species variability in biofilm formation of Porphyromonas gingivalis and partners
Graziela Murta Barbosa   +3 more
doaj   +1 more source

Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway

open access: yesInternational Journal of Oral Science, 2023
Bacteremia induced by periodontal infection is an important factor for periodontitis to threaten general health. P. gingivalis DNA/virulence factors have been found in the brain tissues from patients with Alzheimer’s disease (AD). The blood-brain barrier
Shuang Lei   +8 more
doaj   +1 more source

Role of nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 6 in activation of inflammation in human umbilical vein endothelial cells stimulated by Porphyromonas gingivalis-an in vitro study

open access: yesJournal of Dental Sciences, 2023
Background/purpose: Porphyromonas gingivalis (P. gingivalis) could induce the activation of vascular endothelial cells and promote the formation of atherosclerosis.
Xinzhe Lou   +7 more
doaj   +1 more source

Clinical significance and prognostic value of Porphyromonas gingivalis infection in lung cancer

open access: yesTranslational Oncology, 2021
A variety of pathogenic microorganisms can promote the occurrence and development of malignant tumors by colonizing in the body. It has been shown that Porphyromonas gingivalis (P.
Yiwen Liu   +9 more
doaj   +1 more source

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