Results 11 to 20 of about 52,654 (304)

Role of nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 6 in activation of inflammation in human umbilical vein endothelial cells stimulated by Porphyromonas gingivalis-an in vitro study

Journal of Dental Sciences, 2023
Background/purpose: Porphyromonas gingivalis (P. gingivalis) could induce the activation of vascular endothelial cells and promote the formation of atherosclerosis.
Xinzhe Lou, Jianru Liu, Xiangying Ouyang, Wenyi Liu, Ying Xie, Jinsheng Zhong, Peiying Lv, Shengnan Zhang   +7 more
doaj   +1 more source

Phylogenomic analysis of the Porphyromonas gingivalis - Porphyromonas gulae duo: approaches to the origin of periodontitis

Frontiers in Microbiology, 2023
Porphyromonas gingivalis is an oral human pathogen associated with the onset and progression of periodontitis, a chronic immune-inflammatory disease characterized by the destruction of the teeth-supporting tissue. P.
Mauricio Morales-Olavarría, Josefa Nuñez-Belmar, Dámariz González, Emiliano Vicencio, Jaime Andres Rivas-Pardo, Jaime Andres Rivas-Pardo, Cristian Cortez, Juan P. Cárdenas, Juan P. Cárdenas   +8 more
doaj   +1 more source

The potency of Immunoglobulin Y anti Porphyromonas gingivalis to inhibit the adherence ability of Porphyromonas gingivalis on enterocytes

Dental Journal, 2020
Background: Pophyromonas gingivalis (P. gingivalis) bacteria are the main type of bacterium that cause chronic periodontitis. Immunoglobulin Y (IgY) is a type of immunoglobulin found in poultry, such as chickens and birds.
Nova Andriani Hepitaria, Indeswati Diyatri, Markus Budi Rahardjo, Rini Devijanti Ridwan   +3 more
doaj   +1 more source

Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine-gingipain inhibitor COR388. [PDF]

, 2020
COR388, a small-molecule lysine-gingipain inhibitor, is currently being investigated in a Phase 2/3 clinical trial for Alzheimer's disease (AD) with exploratory endpoints in periodontal disease.
Arastu-Kapur, Shirin, Araujo, Joseph, De Lannoy, Ines AM, Dominy, Stephen S, Ermini, Florian, Haditsch, Ursula, Holsinger, Leslie J, Lynch, Casey, Nguyen, Mai, Raha, Debasish, Ryder, Mark I   +10 more
core   +1 more source

Macrophage Subset Sensitivity to Endotoxin Tolerisation by Porphyromonas gingivalis [PDF]

, 2013
Macrophages (MΦs) determine oral mucosal responses; mediating tolerance to commensal microbes and food whilst maintaining the capacity to activate immune defences to pathogens.
AD Foey, Andrew D. Foey, B Pulendran, C Porta, CW Cutler, E Gemmell, FO Martinez, FR Greten, GD Tribble, GP Garlet, H Okada, HE Barksby, HJ Robertshaw, HM Wilson, J Fletcher, L Duncan, LA Ximenez-Fyvie, LAJ O'Neill, LE Smythies, M Daigneault, M Hirschfeld, M Muthukuru, MA Dobrovolskaia, O Yilmaz, O Yilmaz, P Ezzo, PC Heinrich, PD Smith, R Jotwani, R Merry, RP Darveau, S Sato, SK Biswas, SL Foster, SS Socransky, StJohn Crean, T Hagemann, T Tervonen, Y Liu, YG Kim, Z Xing, Özlem Yilmaz   +41 more
core   +8 more sources

Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis [PDF]

International Immunopharmacology, 2009
Antibody titers to P. gingivalis are increased in patients with rheumatoid arthritis and are associated with disease-specific autoimmunity.Periodontitis (PD) has been implicated as a risk factor for rheumatoid arthritis (RA). We sought to characterize antibody titers to P.
Ted R, Mikuls, Jeffrey B, Payne, Richard A, Reinhardt, Geoffrey M, Thiele, Eileen, Maziarz, Amy C, Cannella, V Michael, Holers, Kristine A, Kuhn, James R, O'Dell   +8 more
openaire   +2 more sources

Localization of P. gingivalis in Preterm Delivery Placenta [PDF]

Journal of Dental Research, 2009
Increasing evidence suggests an association between periodontal disease and adverse pregnancy outcomes. Although infection is considered as a risk factor for preterm delivery, the localization of oral bacteria or their antigens in chorioamnionitis placental tissue has never been demonstrated.
J, Katz, N, Chegini, K T, Shiverick, R J, Lamont   +3 more
openaire   +2 more sources

Bone loss and aggravated autoimmune arthritis in HLA-DRβ1-bearing humanized mice following oral challenge with Porphyromonas gingivalis [PDF]

, 2016
BACKGROUND: The linkage between periodontal disease and rheumatoid arthritis is well established. Commonalities among the two are that both are chronic inflammatory diseases characterized by bone loss, an association with the shared epitope ...
Brand, David D, Dong, Chen, Karydis, Anastasios, Luo, Jiwen, Mydel, Piotr, Novack, Deborah V, Prislovsky, Amanda, Radic, Marko Z, Rosloniec, Edward F, Sandal, Indra, Whittington, Karen B, Zheng, Song Guo   +11 more
core   +2 more sources

Black-pigmented anaerobic bacteria associated with ovine periodontitis [PDF]

, 2017
Periodontitis is a polymicrobial infectious disease that causes occlusion change, tooth loss, difficulty in rumination, and premature culling of animals.
Borsanelli, Ana C., Busin, Valentina, Dutra, Iveraldo S., Gaetti-Jardim, Elerson, Riggio, Marcello P., Schweitzer, Christiane M., Viora, Lorenzo   +6 more
core   +1 more source

Extracellular vesicles of P. gingivalis-infected macrophages induce lung injury

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2021
Periodontal diseases are common inflammatory diseases that are induced by infection with periodontal bacteria such as Porphyromonas gingivalis (Pg). The association between periodontal diseases and many types of systemic diseases has been demonstrated; the term "periodontal medicine" is used to describe how periodontal infection/inflammation may impact
Kayo Yoshida, Kaya Yoshida, Natsumi Fujiwara, Mariko Seyama, Kisho Ono, Hotaka Kawai, Jiajie Guo, Ziyi Wang, Yao Weng, Yaqiong Yu, Yoko Uchida-Fukuhara, Mika Ikegame, Akira Sasaki, Hitoshi Nagatsuka, Hiroshi Kamioka, Hirohiko Okamura, Kazumi Ozaki   +16 more
openaire   +2 more sources