Results 211 to 220 of about 89,060 (300)

Facility Type Predicts Treatment Regimen for Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Treatment landscapes are changing for HPV+ oropharyngeal cancer (OPC) without compromising oncologic outcomes. We aim to analyze treatment trends of HPV+ OPC at academic (ACs) and nonacademic centers (NACs). Methods The National Cancer Database was queried, and multinomial logistic regression was used to predict treatment trends ...
Monica S. Trent, Kelsey Roman, Timothy I. Hsu, Yarah M. Haidar, Tjoson Tjoa   +4 more
wiley   +1 more source

A Non-Channel Function of CFTR: Attenuating Mitochondrial Oxidative Stress and Cardiomyocyte Senescence via Stabilization by USP45. [PDF]

Aging Cell
Chen C, Jiang L, Qiu Y, Liu C, Long X, Wu P, Li L, Xu H, Deng P, Yang L, Jin Q.   +10 more
europepmc   +1 more source

Inflammatory Markers‐Based Surgical Pathological Complete Response Prediction After Neoadjuvant Immunotherapy Combined With Chemotherapy in Head and Neck Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To explore the predictive value of blood routine parameters for surgical pathological complete response (PCR) following neoadjuvant immunotherapy combined with chemotherapy (NICC) in patients with locally advanced head and neck squamous cell carcinoma (LAHNSCC).
Yu‐Dong Ning, Yi‐Xuan Song, Han Li, Yu‐Qin He, Shao‐Yan Liu   +4 more
wiley   +1 more source

Oxidative Stress Induced Senescent Macrophage-Driven Squamous Cell Carcinoma Invasion via Glutamine Metabolic Reprogramming. [PDF]

Aging Cell
Wang S, Mu J, Zhao W, Hu C, Shi X, Zhou H, Liu J, Wu F.   +7 more
europepmc   +1 more source

Epac1 Alleviates Senescence in Auditory Hair Cells via the Ferroptosis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The aim of this study was to investigate the changes in Epac1 and ferroptosis‐related proteins in aged mice and the House Ear Institute‐Organ of Corti 1 (HEI‐OC1) cells, with the goal of elucidating their potential role in age‐related hearing loss. Methods The expression of Epac1 in the cochlea of C57BL/6J mice was examined by using
Wen‐Jun An, Chen‐Yu Xu, Meng‐Ya Shen, Xiao‐Tao Guo, Chun‐Chen Pan, Jing‐Wu Sun, Xiao‐Min Tang, Jia‐Qiang Sun   +7 more
wiley   +1 more source

Spatial Profiling Identified Senescent Cancer-Associated Fibroblasts Localized in the Border Region of Human Pancreatic Ductal Adenocarcinoma. [PDF]

Cell Mol Gastroenterol Hepatol
Harada Y, Masuda A, Matsuura T, Nagata K, Nanno Y, Masamune A, Kodama Y, Hara E, Matsumoto T.   +8 more
europepmc   +1 more source

Poor Outcome of Pediatric Patients with Acute Lymphoblastic Leukemia Harboring Low P16 Deletion Ratio: A Post-Hoc Analysis from a Prospective Cohort. [PDF]

Blood Lymphat Cancer
Qiu KY, Liao XY, Chen HL, Zheng H, Fang JP, Zhou DH.   +5 more
europepmc   +1 more source

Navigating complexity: A relational perspective on generative AI adoption in government

Australian Journal of Public Administration, EarlyView.
Abstract This research note presents preliminary findings from exploratory research examining how Australian public servants understand and use generative AI (GenAI) in government work. Drawing on 37 interviews across 22 agencies, we highlight the importance of a relational view of GenAI adoption, that is, the co‐creation of meanings that emerges from ...
Shibaab Rahman, James Connor, Helen Dickinson, Kate Henne, Vanessa McDermott   +4 more
wiley   +1 more source

JMJD3-driven epigenetic reprogramming of p16^INK4a-positive cells promotes tendon regeneration. [PDF]

Bone Res
Liu X, Lu W, Wang Y, Zhang P, Su Z, Cao T, Zhang Y, Zhao J, Wang J, Xiang H, Huang W, Wang K, Pang S, Chen M, Li Y, Liu S.   +15 more
europepmc   +1 more source

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup, Joachim Boers, Line Winther Gustafson, Berit Andersen, Lone Kjeld Petersen, Pinar Bor, Joost Gribnau, Wim G. V. Quint, Henk Van Den Munckhof, Mette Tranberg, Anne Hammer   +10 more
wiley   +1 more source