Divergent myeloid and lymphoid immune landscapes in HPV/p16 positive and HPV/p16 negative oropharyngeal squamous cell carcinomas and their lymph node metastases. [PDF]
Graessle R +7 more
europepmc +1 more source
Nanopore Sequencing for HPV in Oropharyngeal Squamous Cell Carcinoma and Benign Tonsil Specimens
Abstract Objectives Human papillomavirus (HPV) accounts for the majority of oropharyngeal squamous cell carcinoma (OPSCC) cases in the United States but understanding the prevalence of high‐risk HPV in oropharyngeal tissue remains poor. We evaluated nanopore sequencing, a novel rapid, and long‐read sequencing platform, on OPSCC tissue and tested it in ...
Mikayla G. Hubbard +5 more
wiley +1 more source
Sodium butyrate attenuates D-galactose-induced cellular senescence in WI-38 fibroblasts <i>in vitro</i> via modulation of HDAC activity, Nrf2/ARE pathway, and p53/p21/p16 signaling. [PDF]
Song K.
europepmc +1 more source
Abstract Objective To evaluate how patient circumstances that may influence access to care, including area deprivation index (ADI), distance to care center, and rural/urban status affect stage of presentation for HNSCC. Study Design Retrospective, single‐institution study. Setting Urban, academic tertiary care center. Methods Patients with a history of
Kelly Bridgham +7 more
wiley +1 more source
Spatial distribution and prognostic value of tumor-associated macrophages in head and neck squamous cell carcinomas. [PDF]
Yılmaz Topçuoğlu MS +9 more
europepmc +1 more source
Histiocytosis development and clinical variation through the lens of genomics
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps +3 more
wiley +1 more source
Cancer of unknown primary in the neck-challenging in diagnosis and treatment. [PDF]
Wichmann G, Wald T, Dietz A.
europepmc +1 more source
Synthesis of Poly(Itaconate)s With High Monomer Conversion Applying Emulsion Polymerization
Itaconic acid and its derivatives are a promising and bio‐based substitute for oil‐based polymers such as acrylates. In this study, the optimization of polymerization of itaconic acid esters is described by applying emulsion polymerization leading to high reaction conversions and low residual monomer contents. ABSTRACT Itaconic acid and its derivatives
S. Charlotte Fischer von Mollard +5 more
wiley +1 more source
Squamous Cancers and Precancers of the Vulva: Emerging Diagnostic, Prognostic and Predictive Biomarkers in Pathology. [PDF]
Alsolami S, Ji J, Hoang L.
europepmc +1 more source
Natural Products as Modulators of ABC Transporters in Breast Cancer
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
wiley +1 more source

