Results 161 to 170 of about 217,248 (344)
Advanced Science, EarlyView.This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley +1 more source
P1‐228: Muscarinic receptor 1 agonist activity of novel arecoline derivatives in Alzheimer's dementia models [PDF]
, 2009 Kanchugarakoppal S. Rangappa
openalex +1 more source
Prostaglandin D2 Added during the Differentiation of 3T3-L1 Cells Suppresses Adipogenesis via Dysfunction of D-Prostanoid Receptor P1 and P2 [PDF]
, 2023 Michael N. N. Nartey +5 more
openalex +1 more source
Advanced Science, EarlyView.CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal +3 more
wiley +1 more source
Functional characterization of a conserved pair of NKR‐P1 receptors expressed by NK cells and T lymphocytes in liver and gut [PDF]
, 2014 Lise Kveberg +4 more
openalex +1 more source
Advanced Science, EarlyView.This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang +9 more
wiley +1 more source
P1‐145: HOW DOES OVER‐EXPRESSION OF ALPHA SYNUCLEIN ALTER THE RELEASE OF NEUROTROPHIC FACTORS AND THEIR RECEPTORS IN DIFFERENTIATED SH‐SY5Y CELLS? [PDF]
, 2019 Büşra Şengül +2 more
openalex +1 more source
Advanced Science, EarlyView.The prevailing neglect of cellular hierarchies in current spatial transcriptomics deconvolution often obscures cellular heterogeneity and impedes the identification of fine‐grained subtypes. To address this issue, HIDF employs a cluster‐tree and dual regularization to systematically model cellular hierarchical structures.
Zhiyi Zou +5 more
wiley +1 more source
P1‐133: Functional Acetylcholine receptors are expressed in human embryonic stem cell‐derived neurons [PDF]
, 2008 Mats Nilbratt +4 more
openalex +1 more source
Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Advanced Science, EarlyView.Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source