Results 31 to 40 of about 19,370 (214)

p28-GFP fusion protein form large, mobile intracellular inclusions that are not associated with cell nuclei or mitochondria, and repress the replication of a co-introduced TCV replicon.

, 2017
Also see S3 Fig for the spatial separation of p28-GFP foci relative from ER. A p19-expressing construct was included in all infiltrations. (A) p28-GFP forms dense foci that rival nuclei (DAPI-stained) in size, and spatially separate from mitochondria and
Tea Meulia (490581), Xiao-Feng Zhang (597472), Shaoyan Zhang (363713), Randal Halfmann (3818494), Dawei Li (5704), Feng Qu (107909), Rong Sun (532754), Qin Guo (125106)   +7 more
core   +1 more source

Compared to the N-terminally tagged G11-p28, untagged p28 is less competent at complementing the replication of a p28-defective replicon, but more potent at repressing the replication of another replicon encoding wt p28.

, 2017
(A) Diagrams of the N-terminally tagged G11-p28 construct, and the p28-defective [p28fs]_sg2R replicon. (B) Complementation of [p28fs]_sg2R (top row), and repression of TCV_sg2R, by various p28 derivatives (p28-GFP, untagged p28, and G11-p28).
Tea Meulia (490581), Xiao-Feng Zhang (597472), Shaoyan Zhang (363713), Randal Halfmann (3818494), Dawei Li (5704), Feng Qu (107909), Rong Sun (532754), Qin Guo (125106)   +7 more
core   +1 more source

Secretion of novel SEL1L endogenous variants is promoted by ER stress/UPR via endosomes and shed vesicles in human cancer cells.

PLoS ONE, 2011
We describe here two novel endogenous variants of the human endoplasmic reticulum (ER) cargo receptor SEL1LA, designated p38 and p28. Biochemical and RNA interference studies in tumorigenic and non-tumorigenic cells indicate that p38 and p28 are N ...
Monica Cattaneo, Lavinia Vittoria Lotti, Simone Martino, Massimo Alessio, Antonio Conti, Angela Bachi, Renato Mariani-Costantini, Ida Biunno   +7 more
doaj   +1 more source

A model of TCV p28-mediated SIE.

, 2017
Step 1: the concentration of p28 translated from the genome of primary invader (top right, black dots) is relatively low. They interact with each other relatively slowly, allowing the incorporation of p88, and enclosure of the complex by mitochondrion ...
Tea Meulia (490581), Xiao-Feng Zhang (597472), Shaoyan Zhang (363713), Randal Halfmann (3818494), Dawei Li (5704), Feng Qu (107909), Rong Sun (532754), Qin Guo (125106)   +7 more
core   +1 more source

Structure-based vaccines provide protection in a mouse model of ehrlichiosis. [PDF]

PLoS ONE, 2011
Recent advances in bioinformatics have made it possible to predict the B cell and T cell epitopes of antigenic proteins. This has led to design of peptide based vaccines that are more specific, safe, and easy to produce. The obligately intracellular gram
Sunil Thomas, Nagaraja R Thirumalapura, Patricia A Crocquet-Valdes, Bruce A Luxon, David H Walker   +4 more
doaj   +1 more source

Amino acid sequence of P28-19.

, 2013
(A) P28-19 peptides corresponding to the underlined predicted hydrophilic sequence were synthesized. The peptide corresponding to the bold underlined (55–75) sequence was found to react with antibodies to Ehrlichia as well as to induce antibody ...
David H. Walker (175085), Bruce A. Luxon (132655), Sunil Thomas (86994), Nagaraja R. Thirumalapura (339282), Patricia A. Crocquet-Valdes (339284)   +4 more
core   +1 more source

A New Mechanistic Model for Viral Cross Protection and Superinfection Exclusion

Frontiers in Plant Science, 2018
Plants pre-infected with a mild variant of a virus frequently become protected against more severe variants of the same virus through the cross protection phenomenon first discovered in 1929.
Xiao-Feng Zhang, Shaoyan Zhang, Qin Guo, Rong Sun, Taiyun Wei, Feng Qu   +5 more
doaj   +1 more source

Expectations and Reality: The Lived Experiences of Australians With Psychosocial Disability Within the NDIS

Australian Journal of Social Issues, EarlyView.
ABSTRACT While Australia's National Disability Insurance Scheme (NDIS) was founded on principles of choice and control, for people with significant mental health challenges (what the NDIS calls ‘psychosocial disability’) these ideals often remain elusive. Support systems continue to be fractured and in the context of ongoing policy reforms, it is vital
Joel Hollier, Jennifer Smith‐Merry
wiley   +1 more source

The G11-p28 derivative of p28 does not form intracellular inclusions, but is trans-coalesced by untagged p28 and p28-mCherry.

, 2017
As in previous experiments, a p19-expressing construct was present in all infiltrations. (A) Diagram of the constructs used. Note that the N-terminal G11 tag of G11-p28 does not fluoresce by itself, but becomes fluorescent in the presence of G1-10 ...
Tea Meulia (490581), Xiao-Feng Zhang (597472), Shaoyan Zhang (363713), Randal Halfmann (3818494), Dawei Li (5704), Feng Qu (107909), Rong Sun (532754), Qin Guo (125106)   +7 more
core   +1 more source

Evaluation of Osteogenic Inductivity of a Novel BMP2-Mimicking Peptide P28 and P28-Containing Bone Composite

, 2018
We developed a novel BMP2-mimicking peptide P28, which possesses two distinct special structural elements -- seven repetitive aspartic acids and phosphorylated serine designed to promote affinity to hydroxyapatite as well as nucleation of apatite ...
Cui, Wei, Qu, Yanzhen, Yang, Hu, Yang, Liang, Sun, Tingfang, For full list of authors, see publisher\u27s website.   +5 more
core   +1 more source