Results 21 to 30 of about 19,370 (214)

Image-guided surgery with a new tumour-targeting probe improves the identification of positive margins

open access: yesEBioMedicine, 2022
Summary: Background: Given the lack of visual discrepancy between malignant and surrounding normal tissue, current breast conserving surgery (BCS) is associated with a high re-excision rate. Due to the increasing cases of BCS, a novel method of complete
Masahide Goto   +9 more
doaj   +1 more source

Effect of Dual Endothelin Receptor Antagonist on a Retinal Degeneration Animal Model by Regulating Choroidal Microvascular Morphology

open access: yesJournal of Ophthalmology, 2021
Objective. Clinical studies have found that increasing levels of plasma endothelin-1 (ET-1) might inhibit choroidal blood flow (BF) and promote choroidal vasoconstriction.
Xiaowei Zhu   +6 more
doaj   +1 more source

P28 Marfan syndrome? Think again! [PDF]

open access: yesRheumatology, 2020
Abstract Background A 21 year old male was referred to the adult hypermobility clinic from the local rheumatologist with a suspected diagnosis of Marfan syndrome, based on his body habitus although he had presented to his GP with painful toes. Methods
Hanadi Kazkaz   +3 more
openaire   +1 more source

A self-perpetuating repressive state of a viral replication protein blocks superinfection by the same virus.

open access: yesPLoS Pathogens, 2017
Diverse animal and plant viruses block the re-infection of host cells by the same or highly similar viruses through superinfection exclusion (SIE), a widely observed, yet poorly understood phenomenon. Here we demonstrate that SIE of turnip crinkle virus (
Xiao-Feng Zhang   +7 more
doaj   +1 more source

Surface Plasmon Resonance Sensing of Biorecognition Interactions within the Tumor Suppressor p53 Network

open access: yesSensors, 2017
Surface Plasmon Resonance (SPR) is a powerful technique to study the kinetics of biomolecules undergoing biorecognition processes, particularly suited for protein-protein interactions of biomedical interest. The potentiality of SPR was exploited to sense
Ilaria Moscetti   +2 more
doaj   +1 more source

Identification of Silencing Suppressor Protein Encoded by Strawberry Mottle Virus

open access: yesFrontiers in Plant Science, 2022
Strawberry mottle virus (SMoV) is associated with strawberry decline disease, causing losses to fruit yield and quality. In this study, using a screening system that enables detection of both local and systemic plant host (RNA silencing) defense ...
Lingjiao Fan   +8 more
doaj   +1 more source

Metabolic Profile in Neonatal Pig Hearts

open access: yesFrontiers in Cardiovascular Medicine, 2021
We evaluated the metabolic profile in pig hearts at postnatal day 1, 3, 7, and 28 (P1, P3, P7, and P28, respectively) using a targeted liquid chromatography tandem mass spectrometry assay.
Pengsheng Li   +11 more
doaj   +1 more source

Identification of the murine coronavirus p28 cleavage site [PDF]

open access: yesJournal of Virology, 1995
Mouse hepatitis virus strain A59 encodes a papain-like cysteine proteinase (PLP-1) that, during translation of ORF1a, cleaves p28 from the amino terminus of the growing polypeptide chain. In order to determine the amino acid sequences surrounding the p28 cleavage site, the first 4.6 kb of murine hepatitis virus strain A59 ORF1a was expressed in a cell ...
S A, Hughes, P J, Bonilla, S R, Weiss
openaire   +2 more sources

Expression and purification of toxic anti-breast cancer p28-NRC chimeric protein

open access: yesAdvanced Biomedical Research, 2016
Background: Chimeric proteins consisting of a targeting moiety and a cytotoxic moiety are now under intense research focus for targeted therapy of cancer.
Meysam Soleimani   +3 more
doaj   +1 more source

Sensitivity evaluation of a single-step PCR assay using Ehrlichia canis p28 gene as a target and its application in diagnosis of canine ehrlichiosis Avaliação da sensibilidade da PCR em uma etapa com base no gene p28 de Ehrlichia canis e sua aplicação no diagnóstico da erliquiose canina

open access: yesRevista Brasileira de Parasitologia Veterinária, 2010
The aim of this study was to optimize a PCR assay that amplifies an 843 pb fragment from the p28 gene of Ehrlichia canis and compare it with two other PCR methods used to amplify portions of the 16S rRNA and dsb genes of Ehrlichia.
Andrea Cristina Higa Nakaghi   +6 more
doaj   +1 more source

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