Results 1 to 10 of about 19,370 (214)

GP38, P28-I and P28-II: candidates for a vaccine against Schistosomiasis [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 1987
Three antigens protective against Schistosoma mansoni have been extensively characterized. The schistosomulum surface antigen GP38 possesses an immunodominant carbohydrate epitope of which the structure has been defined.
R. J. Pierce   +9 more
doaj   +5 more sources

Molecular Investigation of the p28 Gene of Ehrlichia canis in Infected Dogs From Ho Chi Minh City, Vietnam [PDF]

open access: yesVeterinary Medicine International
Ehrlichia canis (E. canis) is a tick-borne, obligate intracellular bacterium that causes canine monocytic ehrlichiosis (CME), a widely distributed infectious disease in dogs with variable clinical severity.
Nguyen Thi Lieu Kieu   +3 more
doaj   +3 more sources

P28

open access: yesEJC Supplements, 2015
Melanoma is one of the aggressive cancer types. Mutations that lock the BRAF protein in an active state may cause excessive signaling in the pathway, leading to uncontrolled cell growth and survival.
M. Aksenenko, T. Ruksha
doaj   +2 more sources

Replication of cowpox virus in macrophages is dependent on the host range factor p28/N1R [PDF]

open access: yesVirology Journal, 2021
Zoonotic orthopoxvirus infections continue to represent a threat to human health. The disease caused by distinct orthopoxviruses differs in terms of symptoms and severity, which may be explained by the unique repertoire of virus factors that modulate the
Daniel Bourquain   +5 more
doaj   +2 more sources

p28 Bacterial Peptide, as an Anticancer Agent [PDF]

open access: yesFrontiers in Oncology, 2020
Cancer remains a major cause of morbidity and mortality irrespective of the type of conventional chemotherapy. Therefore, there is an urgent need for new and effective anticancer therapeutic agents. Bacterial proteins and their derivative peptides appear
Atieh Yaghoubi   +9 more
doaj   +3 more sources

In silico design of two novel fusion proteins, p28-IL-24 and p28-M4, targeted to breast cancer cells

open access: yesResearch in Pharmaceutical Sciences, 2020
Background and purpose: An anticancer peptide P28, has shown to be cytolethal on various cancer cells including breast cancer. Moreover, p28 can be alsoused as a targeting moiety in the structure of fusion proteins. IL-24 (or its truncated form, M4) is a
Reza Ghavimi   +4 more
doaj   +4 more sources

Insights into the mechanism regulating the differential expression of the P28-OMP outer membrane proteins in obligatory intracellular pathogen Ehrlichia chaffeensis

open access: yesEmerging Microbes and Infections, 2021
Ehrlichia chaffeensis causes human monocytic ehrlichiosis (HME), which is one of the most prevalent, life-threatening emerging infectious zoonoses. The life cycle of E. chaffeensis includes ticks and mammals, in which E.
Nan Duan   +13 more
doaj   +1 more source

The Effect of Bacterial Peptide p28 on Viability and Apoptosis Status of P53-null HeLa Cells [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2019
Purpose: Despite all the efforts for discovery of efficient anti-cancer therapeutics, cancer is still a major health concern worldwide. p28 is a bacterial small peptide which has been widely investigated due to its preferential cell internalization and ...
Haniyeh Abuei   +6 more
doaj   +1 more source

Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease

open access: yesSignal Transduction and Targeted Therapy, 2022
Interleukin 27 (IL-27), a heterodimeric cytokine composed of Epstein-Barr virus-induced 3 and p28, is a pleiotropic cytokine with both pro-and anti-inflammatory properties.
Huanle Gong   +14 more
doaj   +1 more source

Interleukin-27 Functional Duality Balances Leishmania Infectivity and Pathogenesis

open access: yesFrontiers in Immunology, 2020
IL-27 is a cytokine that exerts diverse effects on the cells of innate and adaptive immune systems. Chiefly expressed in macrophages and dendritic cells during the early phase of Leishmania infection, IL-27 contributes to the protection against L.
Abdollah Jafarzadeh   +9 more
doaj   +1 more source

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