Results 81 to 90 of about 19,370 (214)

‘Being an Outsider’ and ‘Being an Insider’: A Focused Ethnography of Family Members' Visitation Experiences in an Adult ICU

Journal of Advanced Nursing, Volume 82, Issue 7, Page 7441-7452, July 2026.
ABSTRACT Aims To explore how the restricted visitation policy impacts family members' visitation experiences and perceptions in an adult intensive care unit (ICU). Design Focused ethnography. Methods Data collection included 39 observation sessions (totalling 65.3 h), 19 semi‐structured interviews with family members, and document analysis of policies ...
Lian Zhu, Susanne Kean, Catherine Clarissa, Jennifer Tocher   +3 more
wiley   +1 more source

“I'm Not Here to Teach You How to Be Gay:” LGBTQ+ Client Experiences of Othering in Emotionally Focused Couple Therapy

Journal of Marital and Family Therapy, Volume 52, Issue 3, July 2026.
ABSTRACT Despite the increasing emphasis on addressing the intersections of client and therapist identity to improve therapeutic outcomes, therapy clients holding marginalized identities continue to experience othering. Othering is a process that engenders marginalization and inequality based on preconceived group identity, involves the hegemonic ...
Caitlin Edwards, Lekie Dwanyen, Andrea Wittenborn, Robert Allan   +3 more
wiley   +1 more source

Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease

Journal of Anatomy, Volume 249, Issue 1, Page 85-96, July 2026.
The fibrocartilage of the murine glenoid fossa and condyle of the temporomandibular joint are shown to form at distinct times with distinct molecular identities. Changes in the condyle during disease lead to remodelling of the fossa to maintain joint alignment.
Ticha Tuwatnawanit, Denisa Belisova, Zuzana Sumbalova Koledova, Neal Anthwal, Abigail S. Tucker   +4 more
wiley   +1 more source

EXPRESSION OF CANCER-ASSOCIATED PROTEINS IN TISSUES AND BLOOD SERUM FROM PATIENTS WITH RENAL CELL CARCINOMA

Медицинская иммунология, 2014
. Samples of renal cell carcinoma (RCC) and adjacent normal tissues were studied by means of immunoblotting, using monoclonal antibodies [(MKA 1, 1F3-2D4, IgG1 class), MKA 2H6, IgG1 class] against membrane proteins of HEp-2 cells (larynx cancer).
T. S. Bobrova, Yu. V. Chuev
doaj   +1 more source

Detection of MSI signals from peripheral blood for monitoring response to immune checkpoint blockade therapy in patients with advanced microsatellite‐unstable gastrointestinal cancers: A pilot study

International Journal of Cancer, Volume 158, Issue 12, Page 3312-3323, 15 June 2026.
What's new? A substantial proportion of patients with microsatellite‐unstable gastrointestinal adenocarcinomas do not benefit from immunotherapy. This study demonstrates that microsatellite instability can be reliably detected in plasma‐derived extracellular vesicle DNA from patients with microsatellite‐unstable gastrointestinal cancers.
Aysel Ahadova, Lena Bohaumilitzky, Thomas Walle, Joscha A. Kraske, Mirjam Tariverdian, Ulrike Ganserer‐Schmitt, Ingrid Hausser‐Siller, Vera Fuchs, Nina Nelius, Gizem Mehtap Erisen, Johannes Gebert, Albrecht Stenzinger, Dirk Jäger, Magnus von Knebel Doeberitz, Georg Martin Haag, Elena Busch, Matthias Kloor   +16 more
wiley   +1 more source

-fused BMP2-related peptide P28 from small intestinal submucosa/polylactic acid scaffold material for bone tissue regeneration

, 2020
Bone morphogenetic protein 2 (BMP-2) is one of the most important factors for bone tissue formation. However, its use over the past decade has been associated with numerous side effects.
Sheng Yao, Cui, Wei, Zhou, Jinge, Yao, Sheng, Zekang Xiong, Qu, Yanzhen, Liang Yang, Shao, Zengwu, Yang, Liang, Yanzhen Qu, Jinge Zhou, Yu Teng, Xiaodong Guo, Teng, Yu, Zengwu Shao, Kaifang Chen, Wei Cui, Tingfang Sun, Xiong, Zekang, Sun, Tingfang, Chen, Kaifang, Guo, Xiaodong   +21 more
core   +1 more source

Polyphosphates Attenuate Interleukin‐12 Production in Macrophages Infected With Legionella pneumophila

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Legionella pneumophila infection leads to the release of pathogen‐associated molecular patterns, which recruits the adaptor protein MYD88, initiating both activating (e.g., NF‐κB) and inhibitory (e.g., PI3K/AKT) signaling pathways that regulate IL‐12 gene expression.
Kara Vasilew, Archana Jayaraman, Johannes Platten, Shuang Xu, Sarah Josinsky, Julian Roewe, Maximilian Mimmler, Jonathan Kilroy, Fedoua Echahidi, Ziya Kaya, Dario S. Zamboni, Christoph Reinhardt, Markus Bosmann   +12 more
wiley   +1 more source

Morphology of Der2^SCKO and S63del//Der2^SCKO sciatic nerves at P28.

, 2019
(A) Transverse semithin sections from WT, Der2SCKO, S63del and S63del//Der2SCKO P28 sciatic nerves. Arrowheads indicate fibers with similar diameter for myelin thickness comparison. n = 5–6 mice/genotype. Scale bar, 10μm; 100x magnification.
Maurizio D’Antonio (800388), Tatiana Solda (6597458), Francesca Bianchi (316618), Emanuela Pettinato (217795), Ubaldo Del Carro (91152), Maurizio Molinari (224041), Lawrence Wrabetz (47681), Vera G. Volpi (6597452), Cinzia Ferri (254925), Ilaria Fregno (6597455), Cristina Scapin (564586), M. Laura Feltri (47680)   +11 more
core   +1 more source

Production and Evaluation of In-vitro and In-vivo Effects of P28-IL24, a Promising Anti-breast Cancer Fusion Protein

, 2021
Interleukin-24 (IL-24) is known to selectively induce apoptosis in cancer cells through endoplasmic reticulum (ER) stress. However, this protein alone is unable to enter cells and consequently it is not able to inhibit cell proliferation.
Akbari, V., Ghavimi, R., Jahanian-Najafabadi, A.   +2 more
core   +1 more source

Expression and cellular distribution of ubiquitin in response to injury in the developing spinal cord of Monodelphis domestica.

PLoS ONE, 2013
Ubiquitin, an 8.5 kDa protein associated with the proteasome degradation pathway has been recently identified as differentially expressed in segment of cord caudal to site of injury in developing spinal cord.
Natassya M Noor, Kjeld Møllgård, Benjamin J Wheaton, David L Steer, Jessie S Truettner, Katarzyna M Dziegielewska, W Dalton Dietrich, A Ian Smith, Norman R Saunders   +8 more
doaj   +1 more source