Results 101 to 110 of about 39,255 (248)

A P2X receptor-mediated nociceptive afferent pathway to lamina I of the spinal cord

open access: yesMolecular Pain, 2005
Of the six lamina regions in the dorsal horn of the spinal cord, lamina I is a major sensory region involved in nociceptive transmission under both physiological and pathological conditions.
Gu Jianguo G, Chen Meng
doaj   +1 more source

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source

The role of reactive enteric glia‐macrophage interactions in acute and chronic inflammation

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
Abstract Enteric glia are a heterogeneous population of peripheral glia within the enteric nervous system and play pivotal roles in gut homeostasis, tissue integrity, coordination of motility, and intestinal immune responses. Under physiological conditions, they communicate with enteric neurons to control intestinal motility.
Schneider Reiner   +4 more
wiley   +1 more source

P2 receptor mRNA expression profiles in human lymphocytes, monocytes and CD34+ stem and progenitor cells

open access: yesBMC Immunology, 2004
Background Extracellular nucleotides (ATP, ADP, UTP and UDP) exert a wide range of biological effects in blood cells mediated by multiple ionotropic P2X receptors and G protein-coupled P2Y receptors.
Bengtsson Anders   +3 more
doaj   +1 more source

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source

Two-dimensional superintegrable systems from operator algebras in one dimension

open access: yes, 2018
We develop new constructions of 2D classical and quantum superintegrable Hamiltonians allowing separation of variables in Cartesian coordinates. In classical mechanics we start from two functions on a one-dimensional phase space, a natural Hamiltonian $H$
Marquette, Ian   +2 more
core   +1 more source

Optimal Bidding Capacity of Virtual Power Plant Incorporating Power-to-X Resources on Day-Ahead Energy Market

open access: yesEnergies
Sector coupling technology, which is also called power-to-X (P2X) technology, refers to the conversion of renewable energy system (RES) outputs into various forms of energy, enhancing the utility of RESs and facilitating the development of sustainable ...
Kyeong-Hee Cho   +4 more
doaj   +1 more source

Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels

open access: yesCell Reports, 2016
P2X receptors are trimeric ATP-gated cation channels involved in physiological processes ranging widely from neurotransmission to pain and taste signal transduction. The modulation of the channel gating, including that by divalent cations, contributes to
Go Kasuya   +7 more
doaj   +1 more source

Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells [PDF]

open access: yes, 2008
Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling.
Burnstock, G
core  

A shared mechanism for TNP-ATP recognition by members of the P2X receptor family

open access: yesComputational and Structural Biotechnology Journal
P2X receptors (P2X1–7) are non-selective cation channels involved in many physiological activities such as synaptic transmission, immunological modulation, and cardiovascular function.
Xiao-Bo Ma   +11 more
doaj  

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