Results 81 to 90 of about 39,255 (248)

Comparison of P2X and TRPV1 receptors in ganglia or primary culture of trigeminal neurons and their modulation by NGF or serotonin

Molecular Pain, 2006
Background Cultured sensory neurons are a common experimental model to elucidate the molecular mechanisms of pain transduction typically involving activation of ATP-sensitive P2X or capsaicin-sensitive TRPV1 receptors.
Giniatullin Rashid, Nistri Andrea, Zweyer Marina, D'Arco Marianna, Fabbro Alessandra, Simonetti Manuela, Fabbretti Elsa   +6 more
doaj   +1 more source

Non‐ionotropic NMDAR signalling activates Panx1 to induce P2X4R‐dependent long‐term depression in the hippocampus

The Journal of Physiology, EarlyView.
Abstract figure legend Stimulation of the Shaffer collateral pathway at 3 Hz activates non‐ionotropic NMDA receptors. This subsequently leads to Src kinase mediated phosphorylation of pannexin‐1 (Panx1), which releases ATP from the postsynaptic cell. ATP acts as a ligand for P2X4 receptors to induce long‐term depression (LTD). Abstract In recent years,
Allison C. Nielsen, Connor L. Anderson, Carina Ens, Andrew K. J. Boyce, Roger J. Thompson   +4 more
wiley   +1 more source

A note on the infrared behavior of the compactified Ginzburg--Landau model in a magnetic field

, 2011
We consider the Euclidean large-$N$ Ginzburg--Landau model in $D$ dimensions, $d$ ($d\leq D$) of them being compactified. For D=3, the system can be supposed to describe, in the cases of d=1, d=2, and d=3, respectively, a superconducting material in the ...
Linhares, C. A., Malbouisson, A. P. C., Souza, M. L.   +2 more
core   +1 more source

ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages

BMC Immunology, 2008
Background We have previously reported that ATP treatment of M bovis-BCG infected human macrophages induces P2X7 receptor-dependent killing of intracellular mycobacteria.
Croudace Joanne E, Lee Wing-Yiu, Qureshi Omar S, Biswas Debasis, Mura Manuela, Lammas David A   +5 more
doaj   +1 more source

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

The Journal of Physiology, EarlyView.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich, Aleksandra Zieminska, Joshua Gonzalez, Francisca Añazco, Richard Song, Alejandra Arias‐Cavieres, Sara T. Granados, Junyi Zou, Yan Rao, Axel R. Concepcion   +9 more
wiley   +1 more source

Understanding Lorentz violation with Rashba interaction

, 2012
Rashba spin orbit interaction is a well studied effect in condensed matter physics and has important applications in spintronics. The Standard Model Extension (SME) includes a CPT-even term with the coefficient H_{\mu \nu} which leads to the Rashba ...
Bluhm R., MUHAMMAD ADEEL AJAIB, Rashba E. I.   +2 more
core   +1 more source

The role of the purinergic P2X₇ receptor in inflammation

Journal of Inflammation, 2007
The inflammatory process, orchestrated against a variety of injurious stimuli, is composed of three inter-related phases; initiation, propagation and resolution.
Rossi Adriano G, Davidson Donald J, Hodgkiss Joseph P, Sawatzky Deborah A, Sharkey John, Lister Martin F, Finlayson Keith   +6 more
doaj   +1 more source

Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity

The Journal of Physiology, EarlyView.
Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez, Leigh E. Wicki‐Stordeur, Annika V. Ariano, Leigh Anne Swayne   +3 more
wiley   +1 more source

P2X receptors and acupuncture analgesia

Brain Research Bulletin, 2019
Purinergic signaling has recently been suggested to constitute the cellular mechanism underlying acupuncture-induced analgesia (AA). By extending the original hypothesis on endogenous opioids being released during AA, Geoffrey Burnstock and Maiken Nedergaard supplied evidence for the involvement of purinoceptors (P2 and P1/A1 receptors) in the ...
Peter Illes, Peter Illes, Juan Liu, Patrizia Rubini, Yong Tang, Hai-Yan Yin   +5 more
openaire   +3 more sources

Lactate and hydrogen ions play a predominant role in evoking the exercise pressor reflex during ischaemic contractions but not during freely perfused contractions

The Journal of Physiology, EarlyView.
Abstract figure legend The role of lactate and hydrogen ions in evoking the metabolic component of the exercise pressor reflex was studied in rats with either a functional pygm gene (pygm+/+) or with a non‐functional “knocked out” pygm gene (pygm−/−). The pygm gene is responsible for producing the myophosphorylase enzyme which catalyses the breakdown ...
Guillaume P. Ducrocq, Laura Anselmi, Victor Ruiz‐Velasco, Marc P. Kaufman   +3 more
wiley   +1 more source