Results 181 to 190 of about 18,821 (231)

Inhibitory Effect of Clopidogrel, a P2Y₁₂ Receptor Antagonist, on Hematogenic Metastasis in B16-BL6 Mouse Melanoma Cells. [PDF]

In Vivo
Yoshikawa N, Xia M, Nakamura K.
europepmc   +1 more source

Effect of Microglial Purinergic P2Y12 Receptor on Efficiency of Beta-Amyloid Immunotherapy and Aging

Microglia, as the primary immune cells of the central nervous system (CNS), play a pivotal role in the efficiency of Aβ immunotherapy by facilitating β-amyloid clearance and forming a protective barrier around β-amyloid plaques.
Gabr, Amr Ahmed Mohamed
core  

[Treatment] Platelet inhibitors of the P2Y12 receptor

Japanese Journal of Thrombosis and Hemostasis, 2010
openaire   +2 more sources

Inhibiting the P2Y₁₂ Receptor in Megakaryocytes and Platelets Suppresses Interferon-Associated Responses. [PDF]

JACC Basic Transl Sci
Sowa MA, Sun H, Wang TT, Virginio VW, Schlamp F, El Bannoudi H, Cornwell M, Bash H, Izmirly PM, Belmont HM, Ruggles KV, Buyon JP, Voora D, Barrett TJ, Berger JS.   +14 more
europepmc   +1 more source

Synthesis, preclinical evaluation and pilot clinical study of a P2Y₁₂ receptor targeting radiotracer [¹⁸F]QTFT for imaging brain disorders by visualizing anti-inflammatory microglia. [PDF]

Acta Pharm Sin B
Yao B, Kong Y, Li J, Xu F, Deng Y, Chen Y, Chen Y, Chen J, Xu M, Zhu X, Chen L, Xie F, Zhang X, Wang C, Li C.   +14 more
europepmc   +1 more source

Selective Inhibition of P2Y₁ and P2Y₁₂ Receptor Signal Pathways in Platelet Aggregation in Transgenic Cell Lines and Rats by Potassium 2-(1-Hydroxypentyl)-Benzoate, Puerarin and Salvianolic Acid B. [PDF]

CNS Neurosci Ther
Li Y, Wang W, Cai J, Feng N, Xu S, Wang L, Wang X.   +6 more
europepmc   +1 more source

Ticagrelor inverse agonist activity at the P2Y₁₂ receptor is non-reversible versus its endogenous agonist adenosine 5´-diphosphate. [PDF]

Br J Pharmacol
Khalil J, Dimofte T, Roberts T, Keith M, Amaradasa K, Hindle MS, Bancroft S, Hutchinson JL, Naseem K, Johnson T, Mundell SJ.   +10 more
europepmc   +1 more source

Relationship between degree of P2Y12 receptor blockade and inhibition of P2Y12-mediated platelet function

Thrombosis and Haemostasis, 2010
The thienopyridine P2Y12 receptor antagonists clopidogrel and prasugrel prevent arterial thrombosis and are routinely used following percutaneous coronary intervention. However, the optimal level of P2Y12 blockade to effectively inhibit platelet function
Robert J Buckland, Atsuhiro Sugidachi, Robert F Storey   +2 more
exaly   +4 more sources