Results 101 to 110 of about 154,769 (339)
eLife, 2014 Deregulated expression of COX-2 has been causally linked to development, progression, and outcome of several types of human cancer. We describe a novel fundamental level of transcriptional control of COX-2 expression.
Michal Krawczyk, Beverly M Emerson
doaj +1 more source
Analyzing P300 Distractors for Target Reconstruction
, 2018 P300-based brain-computer interfaces (BCIs) are often trained per-user and per-application space. Training such models requires ground truth knowledge of target and non-target stimulus categories during model training, which imparts bias into the model ...
Gordon, Stephen M. +3 more
core +1 more source
Transcription factor dimerization activates the p300 acetyltransferase
Nature, 2018 The transcriptional co-activator p300 is a histone acetyltransferase (HAT) that is typically recruited to transcriptional enhancers and regulates gene expression by acetylating chromatin.
E. Ortega +7 more
semanticscholar +1 more source
Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors
Advanced Science, EarlyView.Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu +11 more
wiley +1 more source
Habituation and Dishabituation of P300
Cognitive and Behavioral Neurology, 2006 We aimed to see the consequences of habituation and posthabituation by means of repeatedly measuring the effects over a longer period.The study was performed on 27 healthy volunteers. The event-related potentials were recorded from the Fz, the Cz, and the Pz electrode sites. The rare tone-frequent tone probability ratio was 20%. All subjects were asked
Keçeci, Hulusi +2 more
openaire +3 more sources
A P300-Based Brain-Computer Interface for Improving Attention
Frontiers in Human Neuroscience, 2019 A Brain-computer Interface (BCI) can be used as a neurofeedback training tool to improve cognitive performance. BCIs aim to improve the effectiveness and efficiency of the conventional neurofeedback methods by focusing on the self-regulation of ...
M. Arvaneh, I. Robertson, T. Ward
semanticscholar +1 more source
Advanced Science, EarlyView.Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao +8 more
wiley +1 more source
Electroencephalographic evidence of vector inversion in antipointing
, 2012 Mirror-symmetrical reaching movements (i.e., antipointing) produce a visual-field-specific pattern of endpoint bias consistent with a perceptual representation of visual space (Heath et al.
Bell, Jon +3 more
core +1 more source
Advanced Science, EarlyView.This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen +7 more
wiley +1 more source
p300 promotes hepatic lipid accumulation in dyslipidemia by regulating SREBP-1c acetylation
陆军军医大学学报Objective To investigate the role of p300 in lipid metabolism disorders. Methods Bioinformatics analysis was performed to analyze the expression patterns of p300 in lipid metabolism disorder-related diseases and its correlation with SREBP-1c and ...
NUHU Abdul-Rauf Nyewneh +2 more
doaj +1 more source