Results 101 to 110 of about 71,455 (301)

ADSC‐Derived CCL8 Regulates HIF‐1α Signaling and Promotes Colorectal Cancer Progression in a 3D Coculture Platform

open access: yesCancer Science, EarlyView.
Schematic illustration showing how CRC‐associated ADSC‐derived CCL8 promotes colorectal cancer cell migration through ERK/HIF‐1α signaling in a 3D coculture platform. ABSTRACT This study aimed to recapitulate adipose‐tumor interactions within the colorectal cancer (CRC) tumor microenvironment (TME) and to elucidate the role of adipose‐derived stem ...
Jeong‐Eun Yun   +7 more
wiley   +1 more source

Operating an Underwater Manipulator via P300 Brainwaves

open access: yes, 2016
It would be difficult and stressful for a single operator to operate an underwater manipulator using his/her both hands in deep sea environments while the operator has to monitor or manipulate additional equipment.
Li, Mengfan   +5 more
core  

Comparative Study of SSVEP- and P300-Based Models for the Telepresence Control of Humanoid Robots

open access: yes, 2015
In this paper, we evaluate the control performance of SSVEP (steady-state visual evoked potential)- and P300-based models using Cerebot-a mind-controlled humanoid robot platform.
Li, Mengfan   +5 more
core   +1 more source

Biogenesis of TNF‐α‐insights into proteostasis and inflammation

open access: yesThe FEBS Journal, EarlyView.
TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar   +3 more
wiley   +1 more source

Electrophysiological methods in the diagnosis of subclinical cognitive impairment in HIV-infected patients

open access: yesЖурнал инфектологии, 2014
With a goal of the early detection of subclinical cognitive impairment and damage of the central nervous system in the early stages HIV infection the complex neurophysiological study (electroencephalogram, cognitive evoked potentials of auditory and ...
O. E. Gurskaya   +6 more
doaj   +1 more source

Lysine lactylation-mediated post-translational modification: Molecular mechanisms and therapeutic target exploration in tumour drug resistance. [PDF]

open access: yesClin Transl Med
Lysine lactylation (Kla) serves as a metabolic–epigenetic switch governed by writer–eraser–reader regulatory systems, directly connecting the Warburg effect to diverse forms of tumour drug resistance. Intratumoural lactylation critically contributes to treatment failure in chemotherapy, targeted therapy and immunotherapy.
Li J   +5 more
europepmc   +2 more sources

A Brain-Computer Interface for robotic arm control

open access: yes, 2011
Lenhardt A. A Brain-Computer Interface for robotic arm control. Bielefeld: Universität Bielefeld; 2011.Brain-Computer Interfaces (BCI) are tools that open a new channel of communication between humans and machines.
Lenhardt, Alexander
core  

P300 ERPs and our flashing timeline for the P300 model.

open access: yes, 2015
(a) A P300 potential, which exhibits a large positive deflection at approximately 300 ms, as represented by the blue curve, is recorded in channel Pz when a subject is staring at a flashing target image.
Wei Li (7081)   +2 more
core   +1 more source

The emerging role of the Hippo signaling pathway in interorgan crosstalk

open access: yesThe FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song   +2 more
wiley   +1 more source

The epigenetic landscape of skeletal muscle in response to exercise and aging

open access: yesThe FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source

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