Results 151 to 160 of about 55,117 (228)

The JAK/STAT Pathway in Cancer: From Molecular Mechanisms to Clinical Applications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Dysregulated JAK/STAT signaling and related genetic mutations are strongly associated with cancer progression, including promoting tumor proliferation, suppressing apoptosis, inducing immune suppression, participating in drug resistance. Based on the function of the JAK/STAT pathway in disease pathogenesis, numerous agents targeting the JAK/STAT ...
Yixing Liao, Qi Wei, Hongjun Song, Hao Zeng, Chang Qi, Yunchang Meng, Yuanyuan Zhang, Yuanyuan Zhang, Weimin Li, Yalun Li, Panwen Tian   +10 more
wiley   +1 more source

African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation. [PDF]

J Mol Cell Biol
Fan J, Yang J, Tian Z, Zhang X, Geng S, Luo J, Boldogh I, Zeng Q, Yin H, Guan G, Niu Q.   +10 more
europepmc   +1 more source

Lithospermic Acid Improves Doxorubicin‐Induced Cardiomyopathy Through Sirtuin‐3‐Mediated Deacetylation of p53

Phytotherapy Research, Volume 40, Issue 3, Page 965-985, March 2026.
Lithospermic acid (LA) inactivates the p53 signaling pathway via directly targeting SIRT3, thereby alleviating oxidative stress and abnormal apoptosis in the progression of doxorubicin (Dox)‐induced cardiomyocytes. ABSTRACT Doxorubicin (Dox)‐induced cardiomyopathy (DIC) is characterized by significant myocardial damage that can progress to dilated ...
Yining Zhao, Tao Xu, Chao Ye, Ke Zhang, Xinyu Heng, Shaohong Huang, Yan Chen, Yitong Guo, Shengyi Shao, Zhi Wen, Chenwen Shao, Xiang Lu, Ning Sun, Hai Yang   +13 more
wiley   +1 more source

CD8a antibody-functionalized biomimetic red blood cell membrane ectosomes delivering C646 reverse CD8⁺ T Cell exhaustion via H3K18la histone delactylation in gastric cardia adenocarcinoma. [PDF]

J Nanobiotechnology
Xiang Z, Zhang X, Liu X, Lv X, Hu Y, Zhang C, Zou C, Wang A, Zhang B, Wang W, Cao G, Jia J.   +11 more
europepmc   +1 more source

Triboelectric Capacitance Supplementation in Energy Storage Composites with Functionalized Carbon Fiber Electrodes

Small, Volume 22, Issue 16, 17 March 2026.
Triboelectric contact electrification evaluation between structural supercapacitor layers using surface‐functionalized carbon fiber electrodes. Electrospun nanofiber separators can aid in capacitance augmentation by leveraging the contact electrification effect of dissimilar materials.
Žan Simon, Bhagya Dharmasiri, Ronald T. Leon, Ben Newman, Fatemeh Mokhtari, Piers Coia, Elmer S. Austria Jr., Behnam Akhavan, Peter C. Sherrell, Amanda V. Ellis, Russell J. Varley, Luke C. Henderson   +11 more
wiley   +1 more source

Disentangling Event-Related Potential and Oscillatory Sources using Time- and Frequency-Domain Source Imaging. [PDF]

Clin Neurophysiol Pract
Depuydt E, De Letter M, van Mierlo P.
europepmc   +1 more source

E1A binding protein p300 (EP300; p300); PTEN ( MMAC1 ; TEP1 ) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

KAT2A Deficiency Suppresses Lung Cancer Progression by Downregulating MYC Through Decreasing MYC Succinylation

Cancer Science, Volume 117, Issue 3, Page 631-643, March 2026.
ABSTRACT Succinylation has been shown to promote lung cancer development, but its mechanism remains incompletely understood. KAT2A, a succinyltransferase, acts as an oncogene in multiple cancers, but its role in mediating lung cancer progression is unclear.
Junping Li, Feng Zhao, Zhongchao Wang, Shaojun Yang, Zhichao Lu, Xiaoyan Li, Jincheng Song, Zhaoxia Dai   +7 more
wiley   +1 more source

Sensory Experience and Motor Signals Shape Auditory Processing in an Independent Manner

European Journal of Neuroscience, Volume 63, Issue 5, March 2026.
This study directly compares how motor and visual cues influence the amplitude of auditory‐evoked responses and how such influence changes as experience with cue‐outcome association is gained. We show that both predictor modality and experience affect the amplitude of auditory‐evoked responses in an independent manner.
Batel Buaron, Roy Mukamel
wiley   +1 more source